Publicação

Is decellularized rabbit dermis a viable option for skin wound healing and regeneration?

Detalhes bibliográficos
Resumo:	Burn wounds remain a major clinical challenge, requiring effective coverage to restore the skin barrier and support healing. Autologous grafts are the standard treatment but are limited in deep or extensive burns [1]. Decellularized allografts and xenografts offer alternatives by removing immunogenic material while preserving ECM components [2]. Considering that xenografts source availability is significantly higher and free of ethical concerns, this study describes for the first time a protocol for decellularizing rabbit dermis, leveraging a valuable agro-food by-product that exceeds 5000 skins/day at the world-leading company Cortadoria Nacional de Pêlo, and studies its potential for skin regeneration.
Autores principais:	Rosadas, Marta
Outros Autores:	Sousa, Teresa; Sousa, Alda; Ribeiro, Viviana P.; Oliveira, Ana L.
Ano:	2025
País:	Portugal
Tipo de documento:	póster não publicado nas atas da conferência
Tipo de acesso:	acesso aberto
Instituição associada:	Universidade Católica Portuguesa
Idioma:	inglês
Origem:	Veritati - Repositório Institucional da Universidade Católica Portuguesa

Descrição
Resumo:	Burn wounds remain a major clinical challenge, requiring effective coverage to restore the skin barrier and support healing. Autologous grafts are the standard treatment but are limited in deep or extensive burns [1]. Decellularized allografts and xenografts offer alternatives by removing immunogenic material while preserving ECM components [2]. Considering that xenografts source availability is significantly higher and free of ethical concerns, this study describes for the first time a protocol for decellularizing rabbit dermis, leveraging a valuable agro-food by-product that exceeds 5000 skins/day at the world-leading company Cortadoria Nacional de Pêlo, and studies its potential for skin regeneration.

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