Publicação
The use of nutraceuticals in veterinary ophthalmology
| Resumo: | ABSTRACT - Nutraceuticals are natural compounds which include supplements and functional foods with potential health benefits. Little is known about their use, namely regarding veterinary ophthalmology. The aim of the present study was to estimate the prevalence of its usage in veterinary ophthalmology in a studied sample. A retrospective study was developed resorting to the database of the Teaching Hospital of the FMV-ULisbon between 2021 and 2023. All the animals who attended a consultation in this period, and, after a complete ophthalmological evaluation, reached a diagnosis of at least one of the five groups of ophthalmic diseases: (1) glaucoma, (2) retinopathies, (3) diseases of the lens or crystalline, (4) ocular surface diseases and (5) nonspecific vision loss, were included in the sample. From these cases, all the animals to which at least one nutraceutical was administered, as therapeutical adjuvant to an ophthalmic disease, were selected. The used nutraceutical compounds were registered. For the recollection and analysis of the data Microsoft Office Excel 2007® and descriptive statistis were used. 1005 clinical cases, of which 90% (907/1005) were dogs, fulfilled the selection criteria. The most common ophthalmic affection in the sample were diseases of the lens (60%, 603/1005), following by retinopathies (17%, 169/1005), ocular surface diseases (15%, 152/1005), glaucoma (5%, 53/1005), and nonspecific vision loss (3% 28/1005). Nutraceuticals were used in 278 animals, representing 28% of prevalence of the use of these compounds in the studied sample. The ophthalmic disease in which nutraceuticals were more frequently prescribed were nonspecific vision loss (100%), followed by retinopathies (43%), ocular surface diseases (34%), glaucoma (25%), and cataracts (18%). The most used nutraceutical was an antioxidant enriched with omega-3 fatty acids and carotenoids, prescribed in 107 cases; followed by another antioxidant enriched with magnesium (91 cases), vitamin A (65 cases), Ginkgo Biloba extract (19 cases), and other supplements including Ursodeoxycholic Acid, Selenium, and Coenzyme Q10. Nowadays, nutraceuticals are being used as therapeutical adjuvants in several ophthalmic diseases such as nonspecific vision loss, retinopathies, ocular surface diseases, glaucoma, and cataracts. However, more clinical studies to assess the indications, effects, safety, and dosage of these compounds should be performed. A well-stablished regulation and control of the commercialization and administration of nutraceuticals is also needed |
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| Autores principais: | Santa-Marta, Teresa Ocaña |
| Assunto: | Nutraceuticals Glaucoma Retinal diseases Ocular surface diseases Cataract Nutracêuticos Glaucoma Retinopatias Doenças da superfície ocular Catarata |
| Ano: | 2024 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | ABSTRACT - Nutraceuticals are natural compounds which include supplements and functional foods with potential health benefits. Little is known about their use, namely regarding veterinary ophthalmology. The aim of the present study was to estimate the prevalence of its usage in veterinary ophthalmology in a studied sample. A retrospective study was developed resorting to the database of the Teaching Hospital of the FMV-ULisbon between 2021 and 2023. All the animals who attended a consultation in this period, and, after a complete ophthalmological evaluation, reached a diagnosis of at least one of the five groups of ophthalmic diseases: (1) glaucoma, (2) retinopathies, (3) diseases of the lens or crystalline, (4) ocular surface diseases and (5) nonspecific vision loss, were included in the sample. From these cases, all the animals to which at least one nutraceutical was administered, as therapeutical adjuvant to an ophthalmic disease, were selected. The used nutraceutical compounds were registered. For the recollection and analysis of the data Microsoft Office Excel 2007® and descriptive statistis were used. 1005 clinical cases, of which 90% (907/1005) were dogs, fulfilled the selection criteria. The most common ophthalmic affection in the sample were diseases of the lens (60%, 603/1005), following by retinopathies (17%, 169/1005), ocular surface diseases (15%, 152/1005), glaucoma (5%, 53/1005), and nonspecific vision loss (3% 28/1005). Nutraceuticals were used in 278 animals, representing 28% of prevalence of the use of these compounds in the studied sample. The ophthalmic disease in which nutraceuticals were more frequently prescribed were nonspecific vision loss (100%), followed by retinopathies (43%), ocular surface diseases (34%), glaucoma (25%), and cataracts (18%). The most used nutraceutical was an antioxidant enriched with omega-3 fatty acids and carotenoids, prescribed in 107 cases; followed by another antioxidant enriched with magnesium (91 cases), vitamin A (65 cases), Ginkgo Biloba extract (19 cases), and other supplements including Ursodeoxycholic Acid, Selenium, and Coenzyme Q10. Nowadays, nutraceuticals are being used as therapeutical adjuvants in several ophthalmic diseases such as nonspecific vision loss, retinopathies, ocular surface diseases, glaucoma, and cataracts. However, more clinical studies to assess the indications, effects, safety, and dosage of these compounds should be performed. A well-stablished regulation and control of the commercialization and administration of nutraceuticals is also needed |
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