Publicação
Behçet Disease – Clinical manifestations of 12 patients of an Autoimmune Disease Unit
| Resumo: | The authors present a retrospective study of 12 patients with Behçet’s disease. All patients fulfilled diagnostic criteria for BD (International Study Group for BD, 1990).All patients were Portuguese and Caucasians. There were 12 patients, 9 female and three male. Mean age at onset of BD was 31.3 years. All patients presented recurrent oral ulceration and 66.7% also had genital ulceration. Nine patients (75%) had ocular involvement. Dermatological manifestation was seen in 58.3%. Neurological involvement appeared in 16.7%. Osteoarticular manifestations were presents in 75%. HLA class I alleles were determined in all patients; HLA-B51 was present in two female patients. Seven patients had familiar history of recurrent oral ulceration but only 1 with BD. Evolution was marked by one eye blindness in one female patient with panuveitis. |
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| Autores principais: | Costa, Cláudia |
| Outros Autores: | Castanheira, Rui; Coelho, Fátima; Dias, Carlos |
| Assunto: | Doença de Behçet uveítes úlceras orais úlceras genitais eritema nodoso vasculite aftas Behçet disease uveitis oral ulceration genital ulceration rythema nodosum vasculitis |
| Ano: | 2010 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Instituição associada: | Sociedade Portuguesa de Medicina Interna |
| Idioma: | português |
| Origem: | Revista Portuguesa de Medicina Interna |
| Resumo: | The authors present a retrospective study of 12 patients with Behçet’s disease. All patients fulfilled diagnostic criteria for BD (International Study Group for BD, 1990).All patients were Portuguese and Caucasians. There were 12 patients, 9 female and three male. Mean age at onset of BD was 31.3 years. All patients presented recurrent oral ulceration and 66.7% also had genital ulceration. Nine patients (75%) had ocular involvement. Dermatological manifestation was seen in 58.3%. Neurological involvement appeared in 16.7%. Osteoarticular manifestations were presents in 75%. HLA class I alleles were determined in all patients; HLA-B51 was present in two female patients. Seven patients had familiar history of recurrent oral ulceration but only 1 with BD. Evolution was marked by one eye blindness in one female patient with panuveitis. |
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