Publicação
Acute brucellosis: a dramatic presentation with septic shock and severe thrombocytopenia
| Resumo: | Brucellosis is an endemic zoonosis in Portugal, progressing as a multisystemic disease with a broad spectrum of clinical manifestations, that can be caused by several species of Brucella, the most common being B. melitensis. Hematological abnormalities, including anemia, leukopenia and thrombocytopenia, may be found during the course of the disease.The authors describe the case of a 53 year-old man, native of Cape Verde and residing in Portugal for 25 years, with a condition of prolonged fever and had a dramatic evolution, with septic shock, severe thrombocytopenia and hemorrhagic dyscrasia. The disease was diagnosed as acute brucellosis, and confirmed through blood cultures. Despite the severity of the clinical situation, the prompt institution of hemodynamic support, blood transfusion, invasive ventilation and appropriate antibiotics led to a satisfactory clinical outcome. The diagnosis of brucellosis can be delayed, particularly when only less common manifestations are present. In this case it was our purpose to highlight the importance of maintaining a high degree of suspicion in order to correctly diagnose cases with less familiar clinical presentations |
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| Autores principais: | Paulino, Maria Carolino |
| Outros Autores: | Mendes, Rita; Póvoa, Pedro; Pacheco, João; Silva, Francisco; Pimenta da Graça, José |
| Assunto: | brucelose trombocitopenia choque séptico brucellosis thrombocytopenia septic shock |
| Ano: | 2011 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Instituição associada: | Sociedade Portuguesa de Medicina Interna |
| Idioma: | português |
| Origem: | Revista Portuguesa de Medicina Interna |
| Resumo: | Brucellosis is an endemic zoonosis in Portugal, progressing as a multisystemic disease with a broad spectrum of clinical manifestations, that can be caused by several species of Brucella, the most common being B. melitensis. Hematological abnormalities, including anemia, leukopenia and thrombocytopenia, may be found during the course of the disease.The authors describe the case of a 53 year-old man, native of Cape Verde and residing in Portugal for 25 years, with a condition of prolonged fever and had a dramatic evolution, with septic shock, severe thrombocytopenia and hemorrhagic dyscrasia. The disease was diagnosed as acute brucellosis, and confirmed through blood cultures. Despite the severity of the clinical situation, the prompt institution of hemodynamic support, blood transfusion, invasive ventilation and appropriate antibiotics led to a satisfactory clinical outcome. The diagnosis of brucellosis can be delayed, particularly when only less common manifestations are present. In this case it was our purpose to highlight the importance of maintaining a high degree of suspicion in order to correctly diagnose cases with less familiar clinical presentations |
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