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Serious complications of low weight molecular heparins-five clinical case rep

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Resumo:During a two year period the authors detected haemorrhagic complications of low weight molecular heparin´s(LWMH) in five patients: 3 females and 2 males with an average age greater than 75.LMWH was used in deep vein thrombosis/ pulmonary thromboembolism (DVT/PTE) suspicion (2), unstable angina (1) and DVT/PTE prevention (2). Adverse effects were spontaneous retroperitoneal bleeding with hypovolaemic shock (1), haemorrhagic suffusion with intramuscular haematoma (1), extensive per umbilical haematoma (1) and haemorrhagic suffusions (2). As reported, additional risk factors for bleeding are: old age, chronic renal insuficiency, chronic hepatic disease, use of salicylates and systemic corticotherapy.The authors concluded that patients undergoing continuous LMWH therapy should be criteriously identified and monitorized to prevent complications
Autores principais:Aragão Carvalho, Filipa
Outros Autores:Ravara, Sofia; Martins, Fernanda; Dutschmann, Luís
Assunto:trombose venosa profunda tromboembolismo pulmonar heparina de baio peso molecular hemorragia deep venous trombosis venous pulmonary thromboembolism low weight molecular heparin bleeding
Ano:2004
País:Portugal
Tipo de documento:artigo
Instituição associada:Sociedade Portuguesa de Medicina Interna
Idioma:português
Origem:Revista Portuguesa de Medicina Interna
Descrição
Resumo:During a two year period the authors detected haemorrhagic complications of low weight molecular heparin´s(LWMH) in five patients: 3 females and 2 males with an average age greater than 75.LMWH was used in deep vein thrombosis/ pulmonary thromboembolism (DVT/PTE) suspicion (2), unstable angina (1) and DVT/PTE prevention (2). Adverse effects were spontaneous retroperitoneal bleeding with hypovolaemic shock (1), haemorrhagic suffusion with intramuscular haematoma (1), extensive per umbilical haematoma (1) and haemorrhagic suffusions (2). As reported, additional risk factors for bleeding are: old age, chronic renal insuficiency, chronic hepatic disease, use of salicylates and systemic corticotherapy.The authors concluded that patients undergoing continuous LMWH therapy should be criteriously identified and monitorized to prevent complications

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