Publicação
Celiac Disease in the Elderly
| Resumo: | Celiac disease is a chronic and autoimmune disorder that can occur at any age. Currently, a quarter of new diagnoses occur after the age of 60. The subtle clinical presentation with micronutrient deficits and osteopenia or osteoporosis, associated with the medical underestimation of this hypothesis leads to its underdiagnosis in the elderly. Celiac disease in old age may have a higher risk of association with autoimmune, lymphoproliferative and cardiovascular diseases, with an impact on morbidity and mortality. Adherence to a gluten-free diet does not seem to be problematic and the quality of life does not appear to decrease. A multidisciplinary follow-up adapted to the patient is essential. In this review, the current evidence of celiac disease in the elderly is systematized, including epidemiology, pathophysiology, clinical manifestations, diagnosis and therapeutic approach, in order to raise awareness and reduce the diagnostic delay. |
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| Autores principais: | Rato, Beatriz |
| Outros Autores: | Teixeira Veríssimo, Manuel |
| Assunto: | Doença Celíaca Idoso Aged Celiac Disease |
| Ano: | 2021 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | unknown |
| Instituição associada: | Sociedade Portuguesa de Medicina Interna |
| Idioma: | português |
| Origem: | Revista Portuguesa de Medicina Interna |
| Resumo: | Celiac disease is a chronic and autoimmune disorder that can occur at any age. Currently, a quarter of new diagnoses occur after the age of 60. The subtle clinical presentation with micronutrient deficits and osteopenia or osteoporosis, associated with the medical underestimation of this hypothesis leads to its underdiagnosis in the elderly. Celiac disease in old age may have a higher risk of association with autoimmune, lymphoproliferative and cardiovascular diseases, with an impact on morbidity and mortality. Adherence to a gluten-free diet does not seem to be problematic and the quality of life does not appear to decrease. A multidisciplinary follow-up adapted to the patient is essential. In this review, the current evidence of celiac disease in the elderly is systematized, including epidemiology, pathophysiology, clinical manifestations, diagnosis and therapeutic approach, in order to raise awareness and reduce the diagnostic delay. |
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