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Optimizing the Use of Renin‑Angiotensin System Inhibition in Advanced Chronic Kidney Disease

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Detalhes bibliográficos
Resumo:Abstract Chronic kidney disease (CKD) affects millions of people worldwide and is a major public health problem. Renin‑angiotensin system inhibitors are the backbone drugs for preventing CKD progression but have potential side effects, such as hyperkalemia or acute decrease in glomerular filtration rate, which can prevent physicians from starting the drugs, or even lead physicians to stop the drug when already in use in advanced CKD patients. In this review, the principal studies performed on this topic are summarized.
Autores principais:Ferreira,Ana Carina
Assunto:Angiotensin Receptor Antagonists/therapeutic use Angiotensin‑Converting Enzyme Inhibitors/therapeutic use Kidney Failure, Chronic/drug therapy Renal Insufficiency, Chronic/drug therapy
Ano:2024
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
Descrição
Resumo:Abstract Chronic kidney disease (CKD) affects millions of people worldwide and is a major public health problem. Renin‑angiotensin system inhibitors are the backbone drugs for preventing CKD progression but have potential side effects, such as hyperkalemia or acute decrease in glomerular filtration rate, which can prevent physicians from starting the drugs, or even lead physicians to stop the drug when already in use in advanced CKD patients. In this review, the principal studies performed on this topic are summarized.

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