Publication

Musculoskeletal manifestations of acute leukemia

Bibliographic Details
Summary:	Abstract Acute lymphoblastic leukemia (ALL) is the most common cause of malignancy in pediatric age. With the exception of musculoskeletal tumors, ALL is one of the malignancies most commonly associated with musculoskeletal symptoms at initial presentation. Some children with ALL are initially referred to Orthopedics for diagnostic evaluation, and a high index of clinical suspicion is required to avoid diagnostic delay. The authors report two cases of children initially diagnosed with a presumed osteoarticular infection, but whose clinical evolution led to the diagnosis of lymphoproliferative disease.
Main Authors:	Cordeiro,Catarina
Other Authors:	Teixeira,Catarina; Jerónimo,Mónica; Silva,Sónia; Azevedo,Joana; Nascimento,João; Carvalho,Marcos; Tarquini,Oliana; Alves,Cristina; Brito,Manuel
Subject:	acute lymphoblastic leukemia musculoskeletal manifestation Pediatrics
Year:	2024
Country:	Portugal
Document type:	report
Access type:	open access
Associated institution:	Fundação para a Ciência e Tecnologia
Language:	English
Origin:	SciELO Portugal

Description
Summary:	Abstract Acute lymphoblastic leukemia (ALL) is the most common cause of malignancy in pediatric age. With the exception of musculoskeletal tumors, ALL is one of the malignancies most commonly associated with musculoskeletal symptoms at initial presentation. Some children with ALL are initially referred to Orthopedics for diagnostic evaluation, and a high index of clinical suspicion is required to avoid diagnostic delay. The authors report two cases of children initially diagnosed with a presumed osteoarticular infection, but whose clinical evolution led to the diagnosis of lymphoproliferative disease.

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