Detalhes bibliográficos
| Resumo: | Renal involvement of antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis typically occurs in the form of a pauci-immune crescentic glomerulonephritis. The finding of some immune complex deposits in these glomerulonephritis is not unusual, but the cases with greater than mild deposition suggest the presence of a second and immune complex related glomerular disease. The significance of the immune complex deposits and their role in ANCA associated vasculitis is still a topic of debate, but higher levels of proteinuria and worse prognosis with respect to renal function have been described in these patients. We report a case of a patient with a known mesangial proliferative glomerulonephritis related to a mixed cryoglobulinemia secondary to a chronic hepatitis C infection that later developed a rapidly progressive glomerulonephritis due to a superimposed anti-myeloperoxidase ANCA positive glomerulonephritis. |
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| Autores principais: | Rodrigues,Luís |
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| Outros Autores: | Aguiar,Brigite; Neves,Marta; Santos,Tânia; Santos,Telma; Gago,José; Sá,Helena; Campos,Mário; Marinho,Carol |
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| Assunto: | ANCA-associated vasculitis immune complex deposits mesangial proliferative glomerulonephritis rapidly progressive glomerulonephritis |
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| Ano: | 2014 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Fundação para a Ciência e Tecnologia |
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| Idioma: | inglês |
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| Origem: | SciELO Portugal |
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