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Endocrinology of calcium homeostasis

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Detalhes bibliográficos
Resumo:Michelle Wheatly reviewed the role of binding proteins in the regulation of calcium homeostasis during periods of net vectorial influx using the crayfish, Procambarus clarkii, as a model. The protein studied were the import and export proteins, epithelial Ca2+ channel (ECaC), sarco/endoplasmic reticulum Ca2+ ATPase (SERCA), plasma membrane Ca2+ ATPase (PMCA) and Na+/Ca2+ exchanger (NCX). The expression of these proteins is a coordinated process at multiple levels including the apical vs. basolateral domains, plasma membranes vs. organelle membranes and transmembrane Ca2+ transporters and binding proteins. An integrative model of cellular Ca2+ homeostasis was presented which took into account the spatial and temporal protein expression during crayfish molting.
Autores principais:Canario, Adelino V. M.
Outros Autores:Flik, G.
Ano:2007
País:Portugal
Tipo de documento:palestra
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Algarve
Idioma:inglês
Origem:Sapientia - Universidade do Algarve
Descrição
Resumo:Michelle Wheatly reviewed the role of binding proteins in the regulation of calcium homeostasis during periods of net vectorial influx using the crayfish, Procambarus clarkii, as a model. The protein studied were the import and export proteins, epithelial Ca2+ channel (ECaC), sarco/endoplasmic reticulum Ca2+ ATPase (SERCA), plasma membrane Ca2+ ATPase (PMCA) and Na+/Ca2+ exchanger (NCX). The expression of these proteins is a coordinated process at multiple levels including the apical vs. basolateral domains, plasma membranes vs. organelle membranes and transmembrane Ca2+ transporters and binding proteins. An integrative model of cellular Ca2+ homeostasis was presented which took into account the spatial and temporal protein expression during crayfish molting.

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