Publicação
PreBötzinger Complex SST + neurons modulate breathing rhythm and pattern
| Resumo: | "Within the respiratory rhythm generator, the preB otzinger Complex (preB otC), a speci c subset of glutamatergic neurons that expresses the inhibitory peptide Somatostatin (SST) is critical for breathing. In rats, these neurons constitute 10 15% of the preB otC and project extensively to a broad range of respiratory-related regions (e.g., B otzinger Complex (B otC) and Retrotrapezoid Nucleus/paraFacial Respiratory Group (RTN/pFRG)). I proposed to investigate the modulatory role of these neurons on breathing, in freely moving mice.(...)" |
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| Autores principais: | Abreu, Raquel Patrícia de Sousa |
| Assunto: | Neurons breathing |
| Ano: | 2016 |
| País: | Portugal |
| Tipo de documento: | tese de doutoramento |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Nova de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório Institucional da UNL |
| Resumo: | "Within the respiratory rhythm generator, the preB otzinger Complex (preB otC), a speci c subset of glutamatergic neurons that expresses the inhibitory peptide Somatostatin (SST) is critical for breathing. In rats, these neurons constitute 10 15% of the preB otC and project extensively to a broad range of respiratory-related regions (e.g., B otzinger Complex (B otC) and Retrotrapezoid Nucleus/paraFacial Respiratory Group (RTN/pFRG)). I proposed to investigate the modulatory role of these neurons on breathing, in freely moving mice.(...)" |
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