Publication
Reactivity of hypervalent iodine(III) reagents bearing a benzylamine with sulfenate salts
| Summary: | The reactivity of our recently disclosed hypervalent iodine reagents (HIRs) bearing a benzylamine with in situ-generated sulfenate salts was investigated. Under the studied conditions sulfonamides have been obtained in up to 52% yield. This reaction has been extended to a variety of HIRs and sulfenate salts to explore the different reactivity of these new reagents. A plausible mechanism is proposed, suggesting a possible radical pathway. |
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| Main Authors: | Dedeiras, Beatriz |
| Other Authors: | Caldeira, Catarina S.; Cunha, José C.; Gomes, Clara S.B.; Marques, M. Manuel B. |
| Subject: | electrophilic amination hypervalent iodine reagents sulfinamide sulfonamide Organic Chemistry |
| Year: | 2024 |
| Country: | Portugal |
| Document type: | article |
| Access type: | open access |
| Associated institution: | Universidade Nova de Lisboa |
| Language: | English |
| Origin: | Repositório Institucional da UNL |
| Summary: | The reactivity of our recently disclosed hypervalent iodine reagents (HIRs) bearing a benzylamine with in situ-generated sulfenate salts was investigated. Under the studied conditions sulfonamides have been obtained in up to 52% yield. This reaction has been extended to a variety of HIRs and sulfenate salts to explore the different reactivity of these new reagents. A plausible mechanism is proposed, suggesting a possible radical pathway. |
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