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Zebrafish avatars as a model for immunotherapy response in bladder cancer

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Bibliographic Details
Summary:"Cancer is a complex entity that dynamically interacts with its host through the tumor microenvironment (TME). Among the network of cells that constitute the TME, immune cells play crucial and contrasting roles in tumor progression. Specifically, immune cells can either fight cancer and eliminate tumor cells or support tumor progression and resistance to therapy. Thus, modulation of the immune system to fight cancer – immunotherapy – represents a revolutionary cancer therapy. (...)"
Main Authors:Martinez-Lopez, Mayra
Subject:cancer tumor microenvironment
Year:2022
Country:Portugal
Document type:doctoral thesis
Access type:open access
Associated institution:Universidade Nova de Lisboa
Language:English
Origin:Repositório Institucional da UNL
Description
Summary:"Cancer is a complex entity that dynamically interacts with its host through the tumor microenvironment (TME). Among the network of cells that constitute the TME, immune cells play crucial and contrasting roles in tumor progression. Specifically, immune cells can either fight cancer and eliminate tumor cells or support tumor progression and resistance to therapy. Thus, modulation of the immune system to fight cancer – immunotherapy – represents a revolutionary cancer therapy. (...)"

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