Publication
Antibacterial silica-borate glasses for bone tissue engineering applications
| Summary: | [Excerpt] One of the major problems in bone tissue engineering/reconstruction isthe possibility of occurring bacterial contamination during the surgicalprocedure. Bacterial strains such asStaphylococcus aureusandPseudo-monas aeruginosaproved to be very difficult to eliminate from bonegrafts [1]. Silica-based bioglasses, namely from the silica-borate systemis gaining interest in thisfield [2]. Knowing in advance that boron hasantibacterial properties [3]; it is relevant to evaluate the anti-bacterialproperties of silica-borate glass formulations [4, 5]. In fact, bioglasseshave been used in bone tissue engineering for several decades due totheir capacity to improve, for example, the scaffolds mechanical perfor-mance, bioactivity or to promote osteoinduction. In this view, the sub-stitution of the current bioglasses with one that, added to the previouslisted properties, present an inherent antibacterial activity is a relevantapproach in the development of bone tissue engineering strategies. [...] |
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| Main Authors: | Fernandes, João S. |
| Other Authors: | Martins, Margarida; Pires, R. A.; Reis, R. L. |
| Subject: | Antibacterial Boro-silicates Glass |
| Year: | 2013 |
| Country: | Portugal |
| Document type: | other |
| Access type: | open access |
| Associated institution: | Universidade do Minho |
| Language: | English |
| Origin: | RepositóriUM - Universidade do Minho |
| Summary: | [Excerpt] One of the major problems in bone tissue engineering/reconstruction isthe possibility of occurring bacterial contamination during the surgicalprocedure. Bacterial strains such asStaphylococcus aureusandPseudo-monas aeruginosaproved to be very difficult to eliminate from bonegrafts [1]. Silica-based bioglasses, namely from the silica-borate systemis gaining interest in thisfield [2]. Knowing in advance that boron hasantibacterial properties [3]; it is relevant to evaluate the anti-bacterialproperties of silica-borate glass formulations [4, 5]. In fact, bioglasseshave been used in bone tissue engineering for several decades due totheir capacity to improve, for example, the scaffolds mechanical perfor-mance, bioactivity or to promote osteoinduction. In this view, the sub-stitution of the current bioglasses with one that, added to the previouslisted properties, present an inherent antibacterial activity is a relevantapproach in the development of bone tissue engineering strategies. [...] |
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