Publicação
Palladium-catalyzed borylation and Suzuki coupling (BSC) to obtain beta-substituted dehydroamino acid derivatives
| Resumo: | Several benzo[b]thienyldehydroamino acids were prepared by one pot palladium-catalyzed borylation and Suzuki coupling (BSC) from bromobenzo[b]thiophenes containing EDG (OMe or Me), as the component to be borylated with pinacolborane, and pure stereoisomers of beta-bromodehydroamino acid derivatives. To our knowledge it is the first time that the BSC reaction involves a non aromatic system. |
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| Autores principais: | Abreu, Ana S. |
| Outros Autores: | Silva, Natália O.; Ferreira, Paula M. T.; Queiroz, Maria João R. P. |
| Assunto: | Benzo[b]thiophenes Borylation Palladium Suzuki coupling Dehydroamino acids |
| Ano: | 2003 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | Several benzo[b]thienyldehydroamino acids were prepared by one pot palladium-catalyzed borylation and Suzuki coupling (BSC) from bromobenzo[b]thiophenes containing EDG (OMe or Me), as the component to be borylated with pinacolborane, and pure stereoisomers of beta-bromodehydroamino acid derivatives. To our knowledge it is the first time that the BSC reaction involves a non aromatic system. |
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