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Lab-on-a-chip technology and microfluidics

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Bibliographic Details
Summary:This chapter presents an overview of the main topics related to microfluidics for pharmaceutical applications. It begins with a general introduction on lab-on-a-chip technology and microfluidics, in which the main definitions, concepts, and characteristics are presented. Further, the main materials and processing techniques used for the development of microfluidic systems are introduced. Finally, the most representative applications are discussed. Applications are focusing on the areas of drug development, drug delivery and diagnosis, cell-based devices, and organs-on-a-chip devices, the latest step toward whole-body models. Thus, a complete overview in the area is provided, followed by a summary and outlook on open questions and future trends.
Main Authors:Francesko, A.
Other Authors:Cardoso, Vanessa Fernandes; Lanceros-Méndez, S.
Subject:Microfluidics Pharmaceutical applications Lab-on-a-chip Organ-on-a-chip Drug testing
Year:2019
Country:Portugal
Document type:book part
Access type:open access
Associated institution:Universidade do Minho
Language:English
Origin:RepositóriUM - Universidade do Minho
Description
Summary:This chapter presents an overview of the main topics related to microfluidics for pharmaceutical applications. It begins with a general introduction on lab-on-a-chip technology and microfluidics, in which the main definitions, concepts, and characteristics are presented. Further, the main materials and processing techniques used for the development of microfluidic systems are introduced. Finally, the most representative applications are discussed. Applications are focusing on the areas of drug development, drug delivery and diagnosis, cell-based devices, and organs-on-a-chip devices, the latest step toward whole-body models. Thus, a complete overview in the area is provided, followed by a summary and outlook on open questions and future trends.

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