Publicação
Assessment of lipid formulations to develop multi-stimuli-responsive solid magnetoliposomes using fluorescence-based methodologies
| Resumo: | This work is focused on the assessment of lipid formulations to design solid magnetoliposomes (SMLs) as multi-stimuli-responsive vesicles for controlled release of doxorubicin (DOX) in pathological areas under the influence of thermal, magnetic, and pH stimuli. The intrinsic fluorescence of DOX can be used as a facilitating tool for DOX-loaded SMLs characterization. Thus, the fluorescence spectroscopy technique was fundamental to evaluating the effect of lipid formulations on SMLs’ properties, such as its encapsulation efficiency. |
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| Autores principais: | Cardoso, Beatriz D. |
| Outros Autores: | Cardoso, Vanessa Fernandes; Lanceros-Méndez, S. |
| Assunto: | magnetic nanoparticles magnetoliposomes doxorubicin cancer therapy Engenharia e Tecnologia::Nanotecnologia Saúde de qualidade |
| Ano: | 2022 |
| País: | Portugal |
| Tipo de documento: | outro |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | This work is focused on the assessment of lipid formulations to design solid magnetoliposomes (SMLs) as multi-stimuli-responsive vesicles for controlled release of doxorubicin (DOX) in pathological areas under the influence of thermal, magnetic, and pH stimuli. The intrinsic fluorescence of DOX can be used as a facilitating tool for DOX-loaded SMLs characterization. Thus, the fluorescence spectroscopy technique was fundamental to evaluating the effect of lipid formulations on SMLs’ properties, such as its encapsulation efficiency. |
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