Detalhes bibliográficos
| Resumo: | The most common and used technique to produce microfluidic devices for biomedical applications is the soft-lithography. However, this is a high cost and time-consuming technique. Recently, manufacturers were able to produce milling tools smaller than 100 m and consequently have promoted the ability of the micromilling machines to fabricate microfluidic devices capable of performing cell separation. In this work, we show the ability of a micromilling machine to manufacture microchannels down to 30 m and also the ability of a microfluidic device to perform partial separation of red blood cells from plasma. Flow visualization and measurements were performed by using a high-speed video microscopy system. Advantages and limitations of the micromilling fabrication process are also presented. |
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| Autores principais: | Singhal, Jaron |
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| Outros Autores: | Pinho, Diana; Lopes, Raquel; Sousa, Patricia C.; Garcia, Valdemar; Schütte, Helmut; Lima, Rui Alberto Madeira Macedo; Gassmann, Stefan |
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| Assunto: | Biomedical applications Blood cells Cell-free layer Cells separation Micromilling Microfluidic devices |
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| Ano: | 2015 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Universidade do Minho |
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| Idioma: | inglês |
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| Origem: | RepositóriUM - Universidade do Minho |
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