Publication
Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review
| Summary: | Social cognitive impairment is a key feature of schizophrenia and social cognition training (SCT) is a promising tool to address these deficits. Neurobiological dysfunction in schizophrenia has been widely researched, but neuronal changes induced by SCT have been scarcely explored. This review aims to assess the neuroplastic effects of SCT in patients with schizophrenia spectrum disorders. PubMed and Web of Science databases were searched for clinical trials testing the effects of SCT in functional and structural brain measurements of adult patients with schizophrenia or schizoaffective disorders. A total of 11 studies were included: five used fMRI, two used EEG and ERP, one used ERP only, two used MEG and one study used MRI. Data extracting and processing regarding sociodemographic and clinical variables, intervention characteristics, neuroimaging procedures, neuroplastic findings, effect sizes and study quality criteria was completed by two raters. Results indicate a wide range of structural and functional changes in numerous regions and circuits of the social brain, including early perceptual areas, the limbic system and prefrontal regions. Despite the small number of trials currently available, evidence suggests that SCT is associated with neuroplastic changes in the social brain and concomitant improvements in social cognitive performance. There is a lack of extensive knowledge about the neural mechanisms that underlie social cognitive enhancement after treatment, but the reported findings may shed light on the neural substrates of social cognitive impairment in schizophrenia and how improved treatment procedures can be developed and applied. |
|---|---|
| Main Authors: | Campos, Carlos |
| Other Authors: | Santos, Susana; Gagen, Emily; Machado, Sérgio; Rocha, Susana; Kurtz, Matthew M; Rocha, Nuno |
| Subject: | Schizophrenia Social cognition Social cognition training Neuroimaging Neuroplasticity |
| Year: | 2016 |
| Country: | Portugal |
| Document type: | article |
| Access type: | open access |
| Associated institution: | Instituto Politécnico do Porto |
| Language: | English |
| Origin: | Repositório Científico do Instituto Politécnico do Porto |
| _version_ | 1877953631921111040 |
|---|---|
| author | Campos, Carlos |
| author2 | Santos, Susana Gagen, Emily Machado, Sérgio Rocha, Susana Kurtz, Matthew M Rocha, Nuno |
| author2_role | author author author author author author |
| author_facet | Campos, Carlos Santos, Susana Gagen, Emily Machado, Sérgio Rocha, Susana Kurtz, Matthew M Rocha, Nuno |
| author_role | author |
| contributor_name_str_mv | REPOSITÓRIO P.PORTO |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Campos, Carlos\",\"Person.identifier.cienciaID\":\"B518-6A52-D50F\",\"Person.identifier.orcid\":\"0000-0002-5966-4050\",\"Person.identifier.scopusAuthorID\":\"56567519500\"},{\"Person.name\":\"Santos, Susana\"},{\"Person.name\":\"Gagen, Emily\"},{\"Person.name\":\"Machado, Sérgio\"},{\"Person.name\":\"Rocha, Susana\"},{\"Person.name\":\"Kurtz, Matthew M\"},{\"Person.name\":\"Rocha, Nuno\",\"Person.identifier.cienciaID\":\"AE16-A494-5F8B\",\"Person.identifier.orcid\":\"0000-0002-3139-2786\",\"Person.identifier.researcherID\":\"M-9821-2013\",\"Person.identifier.scopusAuthorID\":\"32867975300\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | REPOSITÓRIO P.PORTO |
| datacite.creators.creator.creatorName.fl_str_mv | Campos, Carlos Santos, Susana Gagen, Emily Machado, Sérgio Rocha, Susana Kurtz, Matthew M Rocha, Nuno |
| datacite.date.Accepted.fl_str_mv | 2016-09-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2017-08-01T00:30:15Z |
| datacite.date.embargoed.fl_str_mv | 2017-08-01T00:30:15Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Schizophrenia Social cognition Social cognition training Neuroimaging Neuroplasticity |
| datacite.titles.title.fl_str_mv | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| dc.contributor.none.fl_str_mv | REPOSITÓRIO P.PORTO |
| dc.creator.none.fl_str_mv | Campos, Carlos Santos, Susana Gagen, Emily Machado, Sérgio Rocha, Susana Kurtz, Matthew M Rocha, Nuno |
| dc.date.Accepted.fl_str_mv | 2016-09-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2017-08-01T00:30:15Z |
| dc.date.embargoed.fl_str_mv | 2017-08-01T00:30:15Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.22/9462 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Springer Verlag |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Schizophrenia Social cognition Social cognition training Neuroimaging Neuroplasticity |
| dc.title.fl_str_mv | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Social cognitive impairment is a key feature of schizophrenia and social cognition training (SCT) is a promising tool to address these deficits. Neurobiological dysfunction in schizophrenia has been widely researched, but neuronal changes induced by SCT have been scarcely explored. This review aims to assess the neuroplastic effects of SCT in patients with schizophrenia spectrum disorders. PubMed and Web of Science databases were searched for clinical trials testing the effects of SCT in functional and structural brain measurements of adult patients with schizophrenia or schizoaffective disorders. A total of 11 studies were included: five used fMRI, two used EEG and ERP, one used ERP only, two used MEG and one study used MRI. Data extracting and processing regarding sociodemographic and clinical variables, intervention characteristics, neuroimaging procedures, neuroplastic findings, effect sizes and study quality criteria was completed by two raters. Results indicate a wide range of structural and functional changes in numerous regions and circuits of the social brain, including early perceptual areas, the limbic system and prefrontal regions. Despite the small number of trials currently available, evidence suggests that SCT is associated with neuroplastic changes in the social brain and concomitant improvements in social cognitive performance. There is a lack of extensive knowledge about the neural mechanisms that underlie social cognitive enhancement after treatment, but the reported findings may shed light on the neural substrates of social cognitive impairment in schizophrenia and how improved treatment procedures can be developed and applied. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
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| person_str_mv | Campos, Carlos Campos, Carlos https://www.ciencia-id.pt/B518-6A52-D50F B518-6A52-D50F http://orcid.org/0000-0002-5966-4050 0000-0002-5966-4050 Santos, Susana Gagen, Emily Machado, Sérgio Rocha, Susana Kurtz, Matthew M Rocha, Nuno Rocha, Nuno https://www.ciencia-id.pt/AE16-A494-5F8B AE16-A494-5F8B http://orcid.org/0000-0002-3139-2786 0000-0002-3139-2786 |
| publishDate | 2016 |
| publisher.none.fl_str_mv | Springer Verlag |
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| spelling | engSpringer Verlagpt_PTSocial cognitive impairment is a key feature of schizophrenia and social cognition training (SCT) is a promising tool to address these deficits. Neurobiological dysfunction in schizophrenia has been widely researched, but neuronal changes induced by SCT have been scarcely explored. This review aims to assess the neuroplastic effects of SCT in patients with schizophrenia spectrum disorders. PubMed and Web of Science databases were searched for clinical trials testing the effects of SCT in functional and structural brain measurements of adult patients with schizophrenia or schizoaffective disorders. A total of 11 studies were included: five used fMRI, two used EEG and ERP, one used ERP only, two used MEG and one study used MRI. Data extracting and processing regarding sociodemographic and clinical variables, intervention characteristics, neuroimaging procedures, neuroplastic findings, effect sizes and study quality criteria was completed by two raters. Results indicate a wide range of structural and functional changes in numerous regions and circuits of the social brain, including early perceptual areas, the limbic system and prefrontal regions. Despite the small number of trials currently available, evidence suggests that SCT is associated with neuroplastic changes in the social brain and concomitant improvements in social cognitive performance. There is a lack of extensive knowledge about the neural mechanisms that underlie social cognitive enhancement after treatment, but the reported findings may shed light on the neural substrates of social cognitive impairment in schizophrenia and how improved treatment procedures can be developed and applied.application/pdfpt_PTNeuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic ReviewPersonalCampos, CarlosDSpacehttp://dspace.org/items/f9744770-c154-483e-b271-b58d1089d55fDSpacehttp://dspace.org/items/f9744770-c154-483e-b271-b58d1089d55fCamposCarlosCiência IDhttps://www.ciencia-id.ptB518-6A52-D50FORCIDhttp://orcid.org0000-0002-5966-4050Scopus Author IDhttps://www.scopus.com56567519500Santos, SusanaGagen, EmilyMachado, SérgioRocha, SusanaKurtz, Matthew MPersonalRocha, NunoDSpacehttp://dspace.org/items/9e940914-601a-4978-8d5b-74e5ade7ada7DSpacehttp://dspace.org/items/9e940914-601a-4978-8d5b-74e5ade7ada7RochaNunoCiência IDhttps://www.ciencia-id.ptAE16-A494-5F8BORCIDhttp://orcid.org0000-0002-3139-2786Researcher IDhttps://www.researcherid.comM-9821-2013Scopus Author IDhttps://www.scopus.com32867975300HostingInstitutionOrganizationalREPOSITÓRIO P.PORTOe-mailmailto:recipp@sc.ipp.ptrecipp@sc.ipp.ptDOIIsPartOf10.1007/s11065-016-9326-02017-08-01T00:30:15Z2016-092016-09-01T00:00:00ZHandlehttp://hdl.handle.net/10400.22/9462http://purl.org/coar/access_right/c_abf2open accessSchizophreniaSocial cognitionSocial cognition trainingNeuroimagingNeuroplasticity733239 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://recipp.ipp.pt/bitstreams/741b2c5c-4fef-4c28-8ac4-45524a1a3b0c/downloadNeuropsychology Review263310-328328 |
| spellingShingle | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review Campos, Carlos Schizophrenia Social cognition Social cognition training Neuroimaging Neuroplasticity |
| status | SINGLETON |
| subject.fl_str_mv | Schizophrenia Social cognition Social cognition training Neuroimaging Neuroplasticity |
| title | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| title_full | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| title_fullStr | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| title_full_unstemmed | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| title_short | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| title_sort | Neuroplastic Changes Following Social Cognition Training in Schizophrenia: A Systematic Review |
| topic | Schizophrenia Social cognition Social cognition training Neuroimaging Neuroplasticity |
| topic_facet | Schizophrenia Social cognition Social cognition training Neuroimaging Neuroplasticity |
| url | http://hdl.handle.net/10400.22/9462 |
| visible | 1 |
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