Publicação
Influence of Hydrophilic-Lipophilic Balance (HLB) parameter of F98 and F127 polymers on the effectiveness of the formation of gold nanoparticles and encapsulation of the drug capecitabine for the treatment of stomach cancer
| Resumo: | Pluronic F98 and F127 have a higher hydrophilic percentage (70 wt%), in the case of Pluronic F127 and 80% in the case of F98. The article consists of a comparison of the LBL parameter and its influence on the formation of Gold Nanoparticles. These nanoparticles are chosen because they have low toxicity, as well as being effective in medicinal application. Stomach cancer has a high incidence. There is the formation of compounds with a hydrophobic core of polypropylene oxide (PPO) and a hydrophilic crown of polyethylene oxide (PEO). The Pluronic-Nanoparticle system will be gradually released in the patient's body, for less toxicity and greater treatment efficacy. The methodologies used in this first phase are the bibliographic sources and their survey and the use of the main databases for this purpose. |
|---|---|
| Autores principais: | Nascimento, Daniela Macedo |
| Outros Autores: | Macedo, Jeane Pereira; Nascimento, Ademir Macedo |
| Assunto: | Nanopartícula de Ouro Pluronic F127 Pluronic F98 Câncer de estômago. Golden Nanoparticle Pluronic F127 Pluronic F98 Stomach cancer. Pluronic F127 Pluronic F98 Nanopartícula de Oro Cáncer de estómago. |
| Ano: | 2022 |
| País: | Brasil |
| Tipo de documento: | artigo |
| Tipo de acesso: | unknown |
| Instituição associada: | IBICT |
| Idioma: | português |
| Origem: | Oasisbr |
| Resumo: | Pluronic F98 and F127 have a higher hydrophilic percentage (70 wt%), in the case of Pluronic F127 and 80% in the case of F98. The article consists of a comparison of the LBL parameter and its influence on the formation of Gold Nanoparticles. These nanoparticles are chosen because they have low toxicity, as well as being effective in medicinal application. Stomach cancer has a high incidence. There is the formation of compounds with a hydrophobic core of polypropylene oxide (PPO) and a hydrophilic crown of polyethylene oxide (PEO). The Pluronic-Nanoparticle system will be gradually released in the patient's body, for less toxicity and greater treatment efficacy. The methodologies used in this first phase are the bibliographic sources and their survey and the use of the main databases for this purpose. |
|---|
Atividades financiadas
Não foram encontrados projetos financiados.