Bibliographic Details
| Summary: | In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers., against Aedes aegypti, the main vector of dengue. The absolute configuration of these compounds was determined by circular dichroism (CD) spectra. The LC50 values of the compounds evaluated justify the potential of T. toxicaria as a new natural larvicide. |
|---|
| Main Authors: | Vasconcelos,Jackson Nunes e |
|---|
| Other Authors: | Santiago,Gilvandete Maria Pinheiro; Lima,Jefferson Queiroz; Mafezoli,Jair; Lemos,Telma Leda Gomes de; Silva,Francisca Renata Lopes da; Lima,Mary Anne Sousa; Pimenta,Antônia Torres Ávila; Braz-Filho,Raimundo; Arriaga,Angela Martha Campos; Cesarin-Sobrinho,Dari |
|---|
| Subject: | Tephrosia toxicaria rotenoids Aedes aegypti |
|---|
| Year: | 2012 |
|---|
| Country: | Brazil |
|---|
| Document type: | article |
|---|
| Access type: | open access |
|---|
| Associated institution: | IBICT |
|---|
| Language: | English |
|---|
| Origin: | Oasisbr |
|---|