Publication
Review of the medicinal use of Rhaphiodon echinus Schauer (Lamiaceae): biological and pharmacological activities
| Summary: | The objective was to conduct a literature review on the biological and pharmacological activities of Rhaphiodon echinus. This is an integrative review guided by the following question: What is the scientific evidence about the biological and pharmacological activity of R. echinus? The databases MEDLINE, PUBMED, BDENF, SCOPUS and WoS were chosen for the search. A population of 54 studies was identified whose sample was characterized by nine articles. It is suspected that the essential oil and the ethanolic and aqueous extracts of R. echinus have chemical compounds of relevance in phytochemical and pharmacological tests, showing antioxidant and anti-inflammatory activities, besides antimicrobial activity against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa by potentiating the action of drugs such as gentamicin and ciprofloxacin, as well as antifungal activity against Candida albicans. Furthermore, the phytotherapeutic activity of R. echinus in teas, syrups and baths is observed against uterine inflammation, influenza, intestinal colic and urinary tract infection. In summary, it is emphasized that new studies involving R. echinus are needed in the area of ethnobotany in order to better understand its use and interfaces with popular knowledge with a view to its use in clinical practice. |
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| Main Authors: | Cruz Neto, João |
| Other Authors: | Viana, José Wellington Macêdo; Silva, Viviane Bezerra da; Costa, Adrielle Rodrigues; Costa, Maria Haiele Nogueira da; Santos, Marcos Aurélio Figueiredo dos; Rodrigues, Joice Layanne Guimarães; Teixeira, Pedro Hudson Rodrigues; Oliveira, João Paulo Camilo de; Correia, Dennis Bezerra; Menezes, Saulo Almeida de; Santos, Luciano Temoteo dos; Oliveira, Maraiza Gregorio de; Silva Junior, João Pereira da; Gurgel, Catarina Leite; Sampaio, Raimundo Samuel Leite; Lima, Junior Fernandes de; Araújo, Nara Juliana Santos; Almeida-Bezerra, José Weverton |
| Subject: | Sinergismo farmacológico Plantas medicinais Toxicologia Medicamentos fitoterápicos. Sinergismo farmacológico Plantas medicinales Toxicología Fármacos fitoterapéuticos. Drug synergism Plants medicinal Toxicology Phytotherapeutic drugs. |
| Year: | 2021 |
| Country: | Brazil |
| Document type: | article |
| Access type: | unknown |
| Associated institution: | IBICT |
| Language: | Portuguese |
| Origin: | Oasisbr |
| Summary: | The objective was to conduct a literature review on the biological and pharmacological activities of Rhaphiodon echinus. This is an integrative review guided by the following question: What is the scientific evidence about the biological and pharmacological activity of R. echinus? The databases MEDLINE, PUBMED, BDENF, SCOPUS and WoS were chosen for the search. A population of 54 studies was identified whose sample was characterized by nine articles. It is suspected that the essential oil and the ethanolic and aqueous extracts of R. echinus have chemical compounds of relevance in phytochemical and pharmacological tests, showing antioxidant and anti-inflammatory activities, besides antimicrobial activity against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa by potentiating the action of drugs such as gentamicin and ciprofloxacin, as well as antifungal activity against Candida albicans. Furthermore, the phytotherapeutic activity of R. echinus in teas, syrups and baths is observed against uterine inflammation, influenza, intestinal colic and urinary tract infection. In summary, it is emphasized that new studies involving R. echinus are needed in the area of ethnobotany in order to better understand its use and interfaces with popular knowledge with a view to its use in clinical practice. |
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Funded activities
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