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Determination of acetylsalicylic acid in tablets with salicylate ion selective electrode in a Batch Injection Analysis system

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Resumo:The feasibility of the use of a Batch Injection Analysis (BIA) system for potentiometric determination of acetylsalicylic acid in tablets, with a membrane ion selective electrode, was investigated. There is no significant difference between the results obtained by the proposed method and those obtained by the Standard British Pharmacopaeia method12 at the 95% confidence level. Values of 4% and 2.5% for R.S.D. were obtained by the application of the BIA-potentiometric method and for the injections respectively. About 90 determinations per hour can be performed with the proposed BIA potentiometric method.
Autores principais:Fernandes,Julio Cesar B.
Outros Autores:Garcia,Carlos Alexandre B.; Grandin,Luciane A.; Oliveira Neto,Graciliano de; Godinho,Oswaldo E.S.
Assunto:potentiometry ion selective electrode batch injection analysis acetylsalicylic acid
Ano:1998
País:Brasil
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:IBICT
Idioma:inglês
Origem:Oasisbr
Descrição
Resumo:The feasibility of the use of a Batch Injection Analysis (BIA) system for potentiometric determination of acetylsalicylic acid in tablets, with a membrane ion selective electrode, was investigated. There is no significant difference between the results obtained by the proposed method and those obtained by the Standard British Pharmacopaeia method12 at the 95% confidence level. Values of 4% and 2.5% for R.S.D. were obtained by the application of the BIA-potentiometric method and for the injections respectively. About 90 determinations per hour can be performed with the proposed BIA potentiometric method.

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