Detalhes bibliográficos
| Resumo: | This study compares a wound dressing based on bacterial cellulose/collagen (BC/COL) hydrogel in rat dorsum with commercial collagenase ointment and untreated wound. The hydrogel was characterized by Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier transformed - Infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). According to the In vivo test and macroscopic evaluation, BC/COL hydrogel showed a better repair of wounds and promoted statistically significant differences of tissue repair between treatments on the 7th day after surgery. Better quality, quantity and orientation evaluation of collagen fibers (p=0.0001) were observed in the BC/COL hydrogel and collagenase ointment groups in relation to the control group. The BC/COL hydrogel promoted better wound healing than collagenase and the control group, therefore, it can be considered a potential wound dressing for skin regeneration. |
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| Autores principais: | Moraes,Paula Rodrigues Fontes de Sousa |
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| Outros Autores: | Saska,Sybele; Barud,Hernane; Lima,Laís Roncalho de; Martins,Virgínia da Conceição Amaro; Plepis,Ana Maria de Guzzi; Ribeiro,Sidney José Lima; Gaspar,Ana Maria Minarelli |
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| Assunto: | bacterial cellulose collagen hydrogel wound dressing tissue repair |
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| Ano: | 2016 |
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| País: | Brasil |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | IBICT |
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| Idioma: | inglês |
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| Origem: | Oasisbr |
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