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Preparation of PVP hydrogel nanoparticles using lecithin vesicles

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Bibliographic Details
Summary:Hydrogels micro, sub-micro and nanoparticles are of great interest for drug encapsulation and delivery or as embolotherapic agents. In this work it is described the preparation of nano and sub-microparticles of pre-formed, high molecular weight and monomer free poly(N-vinyl-2-pyrrolidone) encapsulated inside the core of lecithin vesicles. The hydrogel particles are formed with a very narrow diameter distribution, of about 800 nm, and a moderate swelling ratio, of approximately 10.
Main Authors:Bueno,Vânia Blasques
Other Authors:Catalani,Luiz Henrique; Daghastanli,Katia Regina Perez; Cuccovia,Iolanda Midea; Chaimovich,Hernan
Subject:PVP hydrogel nanoparticle lecithin vesicle photo-Fenton reaction
Year:2010
Country:Brazil
Document type:article
Access type:open access
Associated institution:IBICT
Language:English
Origin:Oasisbr
Description
Summary:Hydrogels micro, sub-micro and nanoparticles are of great interest for drug encapsulation and delivery or as embolotherapic agents. In this work it is described the preparation of nano and sub-microparticles of pre-formed, high molecular weight and monomer free poly(N-vinyl-2-pyrrolidone) encapsulated inside the core of lecithin vesicles. The hydrogel particles are formed with a very narrow diameter distribution, of about 800 nm, and a moderate swelling ratio, of approximately 10.

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