Publicação
Recent advances in the synthesis of 4H-chromen-4-ones (2012 − 2021)
| Resumo: | Chromones is a family of oxygen heterocyclic compounds whose synthetic versatility and broad spectrum of bioactive properties has been widely reported over the past decade. The increasing number of publications related to the synthesis of this heterocyclic system highlights diverse synthetic approaches, using different starting materials, with novel and efficient synthetic details, applying alternative heating conditions, that provides a huge number of polyfunctionalized 4H-chromen-4-one derivatives. The purpose of this chapter is to present a comprehensive survey of the methodologies developed for the synthesis of 2,3-unsubstituted, 2- and 3-substituted and 2,3-disubstituted 4H-chromen-4-ones, focusing on the literature since 2012, in nearly 450 publications. |
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| Autores principais: | Santos, Clementina M.M. |
| Outros Autores: | Silva, Artur |
| Assunto: | Acetophenone Aldol condensation Baker-Venkataraman Chalcone Chromone Cyclodehydration Enaminone Flavone Isoflavone Multicomponent reaction |
| Ano: | 2022 |
| País: | Portugal |
| Tipo de documento: | capítulo de livro |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Politécnica de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital da UPB |
| Resumo: | Chromones is a family of oxygen heterocyclic compounds whose synthetic versatility and broad spectrum of bioactive properties has been widely reported over the past decade. The increasing number of publications related to the synthesis of this heterocyclic system highlights diverse synthetic approaches, using different starting materials, with novel and efficient synthetic details, applying alternative heating conditions, that provides a huge number of polyfunctionalized 4H-chromen-4-one derivatives. The purpose of this chapter is to present a comprehensive survey of the methodologies developed for the synthesis of 2,3-unsubstituted, 2- and 3-substituted and 2,3-disubstituted 4H-chromen-4-ones, focusing on the literature since 2012, in nearly 450 publications. |
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