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Protein Nanocarriers for Targeted Drug Delivery for Cancer Therapy

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Detalhes bibliográficos
Resumo:This chapter describes how proteins can be used to provide effective targeted nanocarriers for drugs to target tumors. This approach offers an exciting framework for cancer therapies in the future, allowing multiple therapeutic agents and other functions to be combined in the same particle and ensuring a lower toxicity for the patient. The use of proteins provides a rich library of functional molecules to exploit in this methodology. The role of computer simulation to identify the best combination of protein, ligand, and drugs is highlighted.
Autores principais:Kariduraganavar, Mahadevappa Y.
Outros Autores:Heggannavar, Geetha B.; Amado, Sandra; Mitchell, Geoffrey R.
Assunto:Cancer therapy Drug delivery Nanoparticles Proteins Targeted delivery
Ano:2019
País:Portugal
Tipo de documento:capítulo de livro
Tipo de acesso:acesso aberto
Instituição associada:Universidade de Leiria e Oeste
Idioma:inglês
Origem:IC-online
Descrição
Resumo:This chapter describes how proteins can be used to provide effective targeted nanocarriers for drugs to target tumors. This approach offers an exciting framework for cancer therapies in the future, allowing multiple therapeutic agents and other functions to be combined in the same particle and ensuring a lower toxicity for the patient. The use of proteins provides a rich library of functional molecules to exploit in this methodology. The role of computer simulation to identify the best combination of protein, ligand, and drugs is highlighted.

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