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Geographical variation in DXA bone mineral density in young European men and women. Results from the Network in Europe on male osteoporosis (NEMO) study

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Detalhes bibliográficos
Resumo:We collected population-based young normal hip and spine BMD data from 17 centres across Europe to assess between centre differences and to compare reference values with the US NHANES-III data. There was strong evidence of between country heterogeneity, but not between centres within countries. Hip BMD mean values were lower in European women, but SD's differed little from the NHANES-III USA results in both sexes. It may be necessary to adjust NHANES-III based T-scores by adding/subtracting a country-specific adjustment factor.Introduction
Autores principais:Kaptoge, Stephen
Outros Autores:Silva, José A. da; Brixen, Kim; Reid, David M.; Kröger, Heikki; Nielsen, Torben L.; Andersen, Marianne; Hagen, Claus; Lorenc, Roman; Boonen, Steven; Vernejoul, Marie-Christine de; Stepan, Jan J.; Adams, Judith; Kaufman, Jean-Marc; Reeve, Jonathan
Assunto:Bone mineral density (BMD) Dual energy X-ray absorptiometry (DXA) T-score Osteoporosis Young normal
Ano:2008
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade de Coimbra
Idioma:inglês
Origem:Estudo Geral - Universidade de Coimbra
Descrição
Resumo:We collected population-based young normal hip and spine BMD data from 17 centres across Europe to assess between centre differences and to compare reference values with the US NHANES-III data. There was strong evidence of between country heterogeneity, but not between centres within countries. Hip BMD mean values were lower in European women, but SD's differed little from the NHANES-III USA results in both sexes. It may be necessary to adjust NHANES-III based T-scores by adding/subtracting a country-specific adjustment factor.Introduction

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