Publicação
(R,R)-N-phenyl-3,4-bis(diphenylphosphino)pyrrolidine: an N-aryl pyrrolidine ligand for enantioselective transfer hydrogenation
| Resumo: | The N-aryl pyrrolidine diphosphine (R,R)-N-phenyl-3,4-bis(diphenylphosphino)pyrrolidine was obtained from natural tartaric acid. Contrary to our preliminary expectations, this new chiral ligand proved to be less selective than the corresponding N-benzyl pyrrolidine diphosphine. An attempted explanation of the observed behaviour based on the stereochemistry of the ligand as shown by X-ray crystallography is presented. |
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| Autores principais: | Gonsalves, António Manuel d'Albuquerque Rocha |
| Outros Autores: | Serra, Maria Elisa da Silva; Silva, Manuela Ramos; Beja, Ana Matos; Paixão, José António; Veiga, Luiz Alte da |
| Assunto: | Transfer hydrogenation Pyrrolidine diphosphine Asymmetric catalysis Five-membered chelate Rhodium |
| Ano: | 2001 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Coimbra |
| Idioma: | inglês |
| Origem: | Estudo Geral - Universidade de Coimbra |
| Resumo: | The N-aryl pyrrolidine diphosphine (R,R)-N-phenyl-3,4-bis(diphenylphosphino)pyrrolidine was obtained from natural tartaric acid. Contrary to our preliminary expectations, this new chiral ligand proved to be less selective than the corresponding N-benzyl pyrrolidine diphosphine. An attempted explanation of the observed behaviour based on the stereochemistry of the ligand as shown by X-ray crystallography is presented. |
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