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Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report

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Resumo:In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to Bordetella pertussis, are highly susceptible to infection and at risk of severe disease and death. Pertussis associated with pulmonary hypertension in the newborn is often fatal. The authors report a clinical case of severe pertussis-induced respiratory failure associated to severe pulmonary hypertension in a neonate successfully treated with sildenafil and inhaled nitric oxide.
Autores principais:Soares,Sérgia
Outros Autores:Rocha,Gustavo; Pissarra,Susana; Carriço,Ana; Azevedo,Inês; Simões,Joana Sobrinho; Guimarães,Hercília
Assunto:Neonate nitric oxide pertussis pulmonary hypertension sildenafil
Ano:2008
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Soares,Sérgia
author2 Rocha,Gustavo
Pissarra,Susana
Carriço,Ana
Azevedo,Inês
Simões,Joana Sobrinho
Guimarães,Hercília
author2_role author
author
author
author
author
author
author_facet Soares,Sérgia
Rocha,Gustavo
Pissarra,Susana
Carriço,Ana
Azevedo,Inês
Simões,Joana Sobrinho
Guimarães,Hercília
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Soares,Sérgia\"},{\"Person.name\":\"Rocha,Gustavo\"},{\"Person.name\":\"Pissarra,Susana\"},{\"Person.name\":\"Carriço,Ana\"},{\"Person.name\":\"Azevedo,Inês\"},{\"Person.name\":\"Simões,Joana Sobrinho\"},{\"Person.name\":\"Guimarães,Hercília\"}]
datacite.creators.creator.creatorName.fl_str_mv Soares,Sérgia
Rocha,Gustavo
Pissarra,Susana
Carriço,Ana
Azevedo,Inês
Simões,Joana Sobrinho
Guimarães,Hercília
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Neonate
nitric oxide
pertussis
pulmonary hypertension
sildenafil
datacite.titles.title.fl_str_mv Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
dc.creator.none.fl_str_mv Soares,Sérgia
Rocha,Gustavo
Pissarra,Susana
Carriço,Ana
Azevedo,Inês
Simões,Joana Sobrinho
Guimarães,Hercília
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0873-21592008000500007
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Pneumologia
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Revista Portuguesa de Pneumologia v.14 n.5 2008
dc.subject.none.fl_str_mv Neonate
nitric oxide
pertussis
pulmonary hypertension
sildenafil
dc.title.fl_str_mv Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_93fc
description In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to Bordetella pertussis, are highly susceptible to infection and at risk of severe disease and death. Pertussis associated with pulmonary hypertension in the newborn is often fatal. The authors report a clinical case of severe pertussis-induced respiratory failure associated to severe pulmonary hypertension in a neonate successfully treated with sildenafil and inhaled nitric oxide.
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eu_rights_str_mv openAccess
format report
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identifier.url.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0873-21592008000500007
inst_facet_str urn:organizationAcronym:scielo{{{_:::_}}}Fundação para a Ciência e Tecnologia
instacron_str SciELO
institution Fundação para a Ciência e Tecnologia
instname_str Fundação para a Ciência e Tecnologia
language eng
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network_name_str SciELO Portugal
oai_identifier_str oai:scielo:S0873-21592008000500007
organization_str_mv urn:organizationAcronym:scielo
person_str_mv Soares,Sérgia
Rocha,Gustavo
Pissarra,Susana
Carriço,Ana
Azevedo,Inês
Simões,Joana Sobrinho
Guimarães,Hercília
publishDate 2008
publisher.none.fl_str_mv Sociedade Portuguesa de Pneumologia
repo_facet_str urn:repositoryAcronym:scielopt{{{_:::_}}}SciELO Portugal
reponame_str SciELO Portugal
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spelling Pertussis with severe pulmonary hypertension in a newborn with good outcome - case reportSoares,SérgiaRocha,GustavoPissarra,SusanaCarriço,AnaAzevedo,InêsSimões,Joana SobrinhoGuimarães,HercíliaNeonatenitric oxidepertussispulmonary hypertensionsildenafilopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S0873-21592008000500007URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0873-21592008000500007URLHasVersion2008-10-01In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to Bordetella pertussis, are highly susceptible to infection and at risk of severe disease and death. Pertussis associated with pulmonary hypertension in the newborn is often fatal. The authors report a clinical case of severe pertussis-induced respiratory failure associated to severe pulmonary hypertension in a neonate successfully treated with sildenafil and inhaled nitric oxide.Sociedade Portuguesa de PneumologiaRevista Portuguesa de Pneumologia v.14 n.5 2008text/htmlengreporthttp://purl.org/coar/resource_type/c_93fcother research product
spellingShingle Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
Soares,Sérgia
Neonate
nitric oxide
pertussis
pulmonary hypertension
sildenafil
status SINGLETON
subject.fl_str_mv Neonate
nitric oxide
pertussis
pulmonary hypertension
sildenafil
title Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
title_full Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
title_fullStr Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
title_full_unstemmed Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
title_short Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
title_sort Pertussis with severe pulmonary hypertension in a newborn with good outcome - case report
topic Neonate
nitric oxide
pertussis
pulmonary hypertension
sildenafil
topic_facet Neonate
nitric oxide
pertussis
pulmonary hypertension
sildenafil
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0873-21592008000500007
visible 1

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