Publication
Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes
| Summary: | Abstract In the present work, a simple and low-cost protocol for determination of gliclazide using modified screen-printed electrodes (SPE) was reported. The immobilization of magnetic core-shell manganese ferrite nanoparticles (MCSNP) onto SPE provides a unique opportunity for charge transfer process. Consequently, the electroanalytical sensing of gliclazide was explored at the modified SPE surface. The response of the modified electrode was linear, in the concentration range from 0.5 to 300.0 μM, and a detection limit of 100 nM was obtained. The proposed method was successfully employed for gliclazide determination in pharmaceutical and human urine samples. The method showed tremendous reproducibility and intra- and inter-day stability, and has proved to be highly reliable for gliclazide analysis in clinical samples. |
|---|---|
| Main Authors: | Tajik,Somayeh |
| Other Authors: | Mohammadi,Sayed Zia; Beitollahi,Hadi |
| Subject: | Gliclazide determination magnetic core shell nanoparticles screen-printed carbon electrode voltammetry |
| Year: | 2021 |
| Country: | Portugal |
| Document type: | article |
| Access type: | open access |
| Associated institution: | Fundação para a Ciência e Tecnologia |
| Language: | English |
| Origin: | SciELO Portugal |
| _version_ | 1877792035573858304 |
|---|---|
| author | Tajik,Somayeh |
| author2 | Mohammadi,Sayed Zia Beitollahi,Hadi |
| author2_role | author author |
| author_facet | Tajik,Somayeh Mohammadi,Sayed Zia Beitollahi,Hadi |
| author_role | author |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Tajik,Somayeh\"},{\"Person.name\":\"Mohammadi,Sayed Zia\"},{\"Person.name\":\"Beitollahi,Hadi\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Tajik,Somayeh Mohammadi,Sayed Zia Beitollahi,Hadi |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Gliclazide determination magnetic core shell nanoparticles screen-printed carbon electrode voltammetry |
| datacite.titles.title.fl_str_mv | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| dc.creator.none.fl_str_mv | Tajik,Somayeh Mohammadi,Sayed Zia Beitollahi,Hadi |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042021000400265 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Portuguesa de Electroquímica |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Portugaliae Electrochimica Acta v.39 n.4 2021 |
| dc.subject.none.fl_str_mv | Gliclazide determination magnetic core shell nanoparticles screen-printed carbon electrode voltammetry |
| dc.title.fl_str_mv | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Abstract In the present work, a simple and low-cost protocol for determination of gliclazide using modified screen-printed electrodes (SPE) was reported. The immobilization of magnetic core-shell manganese ferrite nanoparticles (MCSNP) onto SPE provides a unique opportunity for charge transfer process. Consequently, the electroanalytical sensing of gliclazide was explored at the modified SPE surface. The response of the modified electrode was linear, in the concentration range from 0.5 to 300.0 μM, and a detection limit of 100 nM was obtained. The proposed method was successfully employed for gliclazide determination in pharmaceutical and human urine samples. The method showed tremendous reproducibility and intra- and inter-day stability, and has proved to be highly reliable for gliclazide analysis in clinical samples. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | scielopt_7a792cc4f139a67c17799b62a6be3143 |
| identifier.url.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042021000400265 |
| inst_facet_str | urn:organizationAcronym:scielo{{{_:::_}}}Fundação para a Ciência e Tecnologia |
| instacron_str | SciELO |
| institution | Fundação para a Ciência e Tecnologia |
| instname_str | Fundação para a Ciência e Tecnologia |
| language | eng |
| network_acronym_str | scielopt |
| network_name_str | SciELO Portugal |
| oai_identifier_str | oai:scielo:S0872-19042021000400265 |
| organization_str_mv | urn:organizationAcronym:scielo |
| person_str_mv | Tajik,Somayeh Mohammadi,Sayed Zia Beitollahi,Hadi |
| publishDate | 2021 |
| publisher.none.fl_str_mv | Sociedade Portuguesa de Electroquímica |
| repo_facet_str | urn:repositoryAcronym:scielopt{{{_:::_}}}SciELO Portugal |
| reponame_str | SciELO Portugal |
| repository_id_str | urn:repositoryAcronym:scielopt |
| service_str_mv | urn:repositoryAcronym:scielopt |
| spelling | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed ElectrodesTajik,SomayehMohammadi,Sayed ZiaBeitollahi,HadiGliclazide determinationmagnetic core shell nanoparticlesscreen-printed carbon electrodevoltammetryopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042021000400265URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042021000400265URLHasVersion2021-08-01Abstract In the present work, a simple and low-cost protocol for determination of gliclazide using modified screen-printed electrodes (SPE) was reported. The immobilization of magnetic core-shell manganese ferrite nanoparticles (MCSNP) onto SPE provides a unique opportunity for charge transfer process. Consequently, the electroanalytical sensing of gliclazide was explored at the modified SPE surface. The response of the modified electrode was linear, in the concentration range from 0.5 to 300.0 μM, and a detection limit of 100 nM was obtained. The proposed method was successfully employed for gliclazide determination in pharmaceutical and human urine samples. The method showed tremendous reproducibility and intra- and inter-day stability, and has proved to be highly reliable for gliclazide analysis in clinical samples.Sociedade Portuguesa de ElectroquímicaPortugaliae Electrochimica Acta v.39 n.4 2021text/htmlengjournal articlehttp://purl.org/coar/resource_type/c_6501literature |
| spellingShingle | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes Tajik,Somayeh Gliclazide determination magnetic core shell nanoparticles screen-printed carbon electrode voltammetry |
| status | SINGLETON |
| subject.fl_str_mv | Gliclazide determination magnetic core shell nanoparticles screen-printed carbon electrode voltammetry |
| title | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| title_full | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| title_fullStr | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| title_full_unstemmed | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| title_short | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| title_sort | Sensitive Determination of Gliclazide in Tablets and Urine Using Modified Screen-Printed Electrodes |
| topic | Gliclazide determination magnetic core shell nanoparticles screen-printed carbon electrode voltammetry |
| topic_facet | Gliclazide determination magnetic core shell nanoparticles screen-printed carbon electrode voltammetry |
| url | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042021000400265 |
| visible | 1 |
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