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Current developments and future perspectives on biotechnology applications of natural deep eutectic systems

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Resumo:Natural Deep Eutectic Systems (NADES) have emerged in the past years as alternative solvents to traditional organic solvents and ionic liquids. NADES are easy to produce, sustainable, biocompatible, eco-friendly, remarkable solubilizing agents, and highly task-specific. The outstanding properties of this new liquid media have attracted the attention of researchers in the last decade in many fields and biotechnology is probably one of the fields where NADES have gained more relevance. Nonetheless, the progress beyond the state of the art in this field is not yet fully explored. Most research papers regarding the use of NADES in biotechnology are related to their use as solubility enhancers for poorly soluble active ingredients, particularly for pharmaceutical applications. However, the applicability of NADES in applications such as cryopreservation, stabilization of proteins and DNA, as well as other biomedical applications, has only recently been explored and presents still a plethora of discoveries to be unravelled. The current developments in this scientific field and future perspectives will be discussed herein.
Autores principais:Jesus, Ana Rita
Outros Autores:Paiva, Alexandre; Duarte, Ana Rita C.
Assunto:Biomedical Biotechnology Green chemistry Natural deep eutectic systems Catalysis Chemistry (miscellaneous) Waste Management and Disposal Process Chemistry and Technology Management, Monitoring, Policy and Law
Ano:2023
País:Portugal
Tipo de documento:recensão
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
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author Jesus, Ana Rita
author2 Paiva, Alexandre
Duarte, Ana Rita C.
author2_role author
author
author_facet Jesus, Ana Rita
Paiva, Alexandre
Duarte, Ana Rita C.
author_role author
contributor_name_str_mv LAQV@REQUIMTE
Elsevier BV
RUN
country_str PT
creators_json_txt [{\"Person.name\":\"Jesus, Ana Rita\"},{\"Person.name\":\"Paiva, Alexandre\"},{\"Person.name\":\"Duarte, Ana Rita C.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv LAQV@REQUIMTE
Elsevier BV
RUN
datacite.creators.creator.creatorName.fl_str_mv Jesus, Ana Rita
Paiva, Alexandre
Duarte, Ana Rita C.
datacite.date.Accepted.fl_str_mv 2023-02-01T00:00:00Z
datacite.date.available.fl_str_mv 2023-07-03T22:15:49Z
datacite.date.embargoed.fl_str_mv 2023-07-03T22:15:49Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Biomedical
Biotechnology
Green chemistry
Natural deep eutectic systems
Catalysis
Chemistry (miscellaneous)
Waste Management and Disposal
Process Chemistry and Technology
Management, Monitoring, Policy and Law
datacite.titles.title.fl_str_mv Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
Elsevier BV
RUN
dc.creator.none.fl_str_mv Jesus, Ana Rita
Paiva, Alexandre
Duarte, Ana Rita C.
dc.date.Accepted.fl_str_mv 2023-02-01T00:00:00Z
dc.date.available.fl_str_mv 2023-07-03T22:15:49Z
dc.date.embargoed.fl_str_mv 2023-07-03T22:15:49Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10362/154764
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Biomedical
Biotechnology
Green chemistry
Natural deep eutectic systems
Catalysis
Chemistry (miscellaneous)
Waste Management and Disposal
Process Chemistry and Technology
Management, Monitoring, Policy and Law
dc.title.fl_str_mv Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_efa0
description Natural Deep Eutectic Systems (NADES) have emerged in the past years as alternative solvents to traditional organic solvents and ionic liquids. NADES are easy to produce, sustainable, biocompatible, eco-friendly, remarkable solubilizing agents, and highly task-specific. The outstanding properties of this new liquid media have attracted the attention of researchers in the last decade in many fields and biotechnology is probably one of the fields where NADES have gained more relevance. Nonetheless, the progress beyond the state of the art in this field is not yet fully explored. Most research papers regarding the use of NADES in biotechnology are related to their use as solubility enhancers for poorly soluble active ingredients, particularly for pharmaceutical applications. However, the applicability of NADES in applications such as cryopreservation, stabilization of proteins and DNA, as well as other biomedical applications, has only recently been explored and presents still a plethora of discoveries to be unravelled. The current developments in this scientific field and future perspectives will be discussed herein.
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eu_rights_str_mv openAccess
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inst_facet_str urn:organizationAcronym:unl{{{_:::_}}}Universidade Nova de Lisboa
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instname_str Universidade Nova de Lisboa
language eng
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oai_identifier_str oai:run.unl.pt:10362/154764
organization_str_mv urn:organizationAcronym:unl
person_str_mv Jesus, Ana Rita
Paiva, Alexandre
Duarte, Ana Rita C.
publishDate 2023
repo_facet_str urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL
reponame_str Repositório Institucional da UNL
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spelling engenNatural Deep Eutectic Systems (NADES) have emerged in the past years as alternative solvents to traditional organic solvents and ionic liquids. NADES are easy to produce, sustainable, biocompatible, eco-friendly, remarkable solubilizing agents, and highly task-specific. The outstanding properties of this new liquid media have attracted the attention of researchers in the last decade in many fields and biotechnology is probably one of the fields where NADES have gained more relevance. Nonetheless, the progress beyond the state of the art in this field is not yet fully explored. Most research papers regarding the use of NADES in biotechnology are related to their use as solubility enhancers for poorly soluble active ingredients, particularly for pharmaceutical applications. However, the applicability of NADES in applications such as cryopreservation, stabilization of proteins and DNA, as well as other biomedical applications, has only recently been explored and presents still a plethora of discoveries to be unravelled. The current developments in this scientific field and future perspectives will be discussed herein.application/pdfenCurrent developments and future perspectives on biotechnology applications of natural deep eutectic systemsJesus, Ana RitaPaiva, AlexandreDuarte, Ana Rita C.LAQV@REQUIMTEElsevier BVHostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptISSNIsPartOf2452-2236URNIsPartOfPURE: 64724173URNIsPartOfPURE UUID: af71181f-7c51-48c1-a132-916c40e98b7fURNIsPartOfScopus: 85144304045URNIsPartOfWOS: 000907039900001DOIIsPartOf10.1016/j.cogsc.2022.1007312023-07-03T22:15:49Z2023-022023-02-01T00:00:00ZHandlehttp://hdl.handle.net/10362/154764http://purl.org/coar/access_right/c_abf2open accessBiomedicalBiotechnologyGreen chemistryNatural deep eutectic systemsCatalysisChemistry (miscellaneous)Waste Management and DisposalProcess Chemistry and TechnologyManagement, Monitoring, Policy and Law531205 bytesother research producthttp://purl.org/coar/resource_type/c_efa0reviewhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/3b2a1b3f-b56a-42ad-9b10-2964f617b30a/download
spellingShingle Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
Jesus, Ana Rita
Biomedical
Biotechnology
Green chemistry
Natural deep eutectic systems
Catalysis
Chemistry (miscellaneous)
Waste Management and Disposal
Process Chemistry and Technology
Management, Monitoring, Policy and Law
status SINGLETON
subject.fl_str_mv Biomedical
Biotechnology
Green chemistry
Natural deep eutectic systems
Catalysis
Chemistry (miscellaneous)
Waste Management and Disposal
Process Chemistry and Technology
Management, Monitoring, Policy and Law
title Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
title_full Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
title_fullStr Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
title_full_unstemmed Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
title_short Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
title_sort Current developments and future perspectives on biotechnology applications of natural deep eutectic systems
topic Biomedical
Biotechnology
Green chemistry
Natural deep eutectic systems
Catalysis
Chemistry (miscellaneous)
Waste Management and Disposal
Process Chemistry and Technology
Management, Monitoring, Policy and Law
topic_facet Biomedical
Biotechnology
Green chemistry
Natural deep eutectic systems
Catalysis
Chemistry (miscellaneous)
Waste Management and Disposal
Process Chemistry and Technology
Management, Monitoring, Policy and Law
url http://hdl.handle.net/10362/154764
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