Publicação
Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning
| Resumo: | Functionalized electrospun fibers are of great interest for biomedical applications such as in the design of drug delivery systems. Nevertheless, in some cases the molecules of interest have poor solubility in water or have high melting temperatures. These drawbacks can be overcome using deep eutectic solvents. In this work, poly(vinyl alcohol) (PVA), a common biodegradable biopolymer, was used to produce new functionalized fibers with the eutectic mixture choline chloride:citric acid in a molar ratio of (1:1) ChCl:CA (1:1), which was used as a model system. Fibers were produced from an aqueous solution with 7.8% (w/v) and 9.8% (w/v) of 95% hydrolyzed PVA and a 2% (v/v) of ChCl:CA (1:1). Smooth, uniform fibers with an average diameter of 0.4 μm were obtained with a content of 19.8 wt % of ChCl:CA (1:1) encapsulated |
|---|---|
| Autores principais: | Mano, Francisca |
| Outros Autores: | Aroso, Ivo Manuel Ascensão; Barreiros, Susana; Borges, João Paulo; Reis, R. L.; Duarte, Ana Rita C.; Paiva, Alexandre |
| Assunto: | Electrospinning Natural Deep-eutectic solvents Poly(vinyl alcohol) Ciências Médicas::Biotecnologia Médica |
| Ano: | 2015 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1877774533434277888 |
|---|---|
| author | Mano, Francisca |
| author2 | Aroso, Ivo Manuel Ascensão Barreiros, Susana Borges, João Paulo Reis, R. L. Duarte, Ana Rita C. Paiva, Alexandre |
| author2_role | author author author author author author |
| author_facet | Mano, Francisca Aroso, Ivo Manuel Ascensão Barreiros, Susana Borges, João Paulo Reis, R. L. Duarte, Ana Rita C. Paiva, Alexandre |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Mano, Francisca\"},{\"Person.name\":\"Aroso, Ivo Manuel Ascensão\"},{\"Person.name\":\"Barreiros, Susana\"},{\"Person.name\":\"Borges, João Paulo\"},{\"Person.name\":\"Reis, R. L.\"},{\"Person.name\":\"Duarte, Ana Rita C.\"},{\"Person.name\":\"Paiva, Alexandre\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Mano, Francisca Aroso, Ivo Manuel Ascensão Barreiros, Susana Borges, João Paulo Reis, R. L. Duarte, Ana Rita C. Paiva, Alexandre |
| datacite.date.Accepted.fl_str_mv | 2015-09-01T00:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Electrospinning Natural Deep-eutectic solvents Poly(vinyl alcohol) Ciências Médicas::Biotecnologia Médica |
| datacite.titles.title.fl_str_mv | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Mano, Francisca Aroso, Ivo Manuel Ascensão Barreiros, Susana Borges, João Paulo Reis, R. L. Duarte, Ana Rita C. Paiva, Alexandre |
| dc.date.Accepted.fl_str_mv | 2015-09-01T00:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/38366 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | American Chemical Society |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Electrospinning Natural Deep-eutectic solvents Poly(vinyl alcohol) Ciências Médicas::Biotecnologia Médica |
| dc.title.fl_str_mv | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Functionalized electrospun fibers are of great interest for biomedical applications such as in the design of drug delivery systems. Nevertheless, in some cases the molecules of interest have poor solubility in water or have high melting temperatures. These drawbacks can be overcome using deep eutectic solvents. In this work, poly(vinyl alcohol) (PVA), a common biodegradable biopolymer, was used to produce new functionalized fibers with the eutectic mixture choline chloride:citric acid in a molar ratio of (1:1) ChCl:CA (1:1), which was used as a model system. Fibers were produced from an aqueous solution with 7.8% (w/v) and 9.8% (w/v) of 95% hydrolyzed PVA and a 2% (v/v) of ChCl:CA (1:1). Smooth, uniform fibers with an average diameter of 0.4 μm were obtained with a content of 19.8 wt % of ChCl:CA (1:1) encapsulated |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | rum_fe4fceda9376c11da46c33cb5f30c461 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/38366 |
| inst_facet_str | urn:organizationAcronym:repositorium{{{_:::_}}}Universidade do Minho |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/38366 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Mano, Francisca Aroso, Ivo Manuel Ascensão Barreiros, Susana Borges, João Paulo Reis, R. L. Duarte, Ana Rita C. Paiva, Alexandre |
| publishDate | 2015 |
| publisher.none.fl_str_mv | American Chemical Society |
| repo_facet_str | urn:repositoryAcronym:rum{{{_:::_}}}RepositóriUM - Universidade do Minho |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engAmerican Chemical SocietyporFunctionalized electrospun fibers are of great interest for biomedical applications such as in the design of drug delivery systems. Nevertheless, in some cases the molecules of interest have poor solubility in water or have high melting temperatures. These drawbacks can be overcome using deep eutectic solvents. In this work, poly(vinyl alcohol) (PVA), a common biodegradable biopolymer, was used to produce new functionalized fibers with the eutectic mixture choline chloride:citric acid in a molar ratio of (1:1) ChCl:CA (1:1), which was used as a model system. Fibers were produced from an aqueous solution with 7.8% (w/v) and 9.8% (w/v) of 95% hydrolyzed PVA and a 2% (v/v) of ChCl:CA (1:1). Smooth, uniform fibers with an average diameter of 0.4 μm were obtained with a content of 19.8 wt % of ChCl:CA (1:1) encapsulatedapplication/pdfporProduction of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinningMano, FranciscaAroso, Ivo Manuel AscensãoBarreiros, SusanaBorges, João PauloReis, R. L.Duarte, Ana Rita C.Paiva, AlexandreHostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptCITATIONMano F., Aroso I. M., Barreiros S., Borges J. P., Reis R. L., Duarte A. R. C., Paiva A. Production of Poly(vinyl alcohol) (PVA) Fibers with Encapsulated Natural Deep Eutectic Solvent (NADES) Using Electrospinning , ACS Sustainable Chemistry & Engineering, doi: DOI:10.1021/acssuschemeng.5b00613 , 2015ISSNIsPartOf2168-0485DOIIsPartOf10.1021/acssuschemeng.5b006132015-092015-09-01T00:00:00ZHandlehttps://hdl.handle.net/1822/38366http://purl.org/coar/access_right/c_abf2open accessElectrospinningNatural Deep-eutectic solventsPoly(vinyl alcohol)http://www.oecd.org/science/inno/38235147.pdfFields of Science and Technology (FOS)Ciências Médicas::Biotecnologia Médica2565030 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdfhttps://repositorium.uminho.pt/bitstreams/75fff936-142f-4a07-81c9-4fa14ef78a06/download |
| spellingShingle | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning Mano, Francisca Electrospinning Natural Deep-eutectic solvents Poly(vinyl alcohol) Ciências Médicas::Biotecnologia Médica |
| status | SINGLETON |
| subject.fl_str_mv | Electrospinning Natural Deep-eutectic solvents Poly(vinyl alcohol) |
| subject.other.fl_str_mv | Ciências Médicas::Biotecnologia Médica |
| title | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| title_full | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| title_fullStr | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| title_full_unstemmed | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| title_short | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| title_sort | Production of Poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning |
| topic | Electrospinning Natural Deep-eutectic solvents Poly(vinyl alcohol) Ciências Médicas::Biotecnologia Médica |
| topic_facet | Electrospinning Natural Deep-eutectic solvents Poly(vinyl alcohol) Ciências Médicas::Biotecnologia Médica |
| url | https://hdl.handle.net/1822/38366 |
| visible | 1 |
Atividades financiadas
Não foram encontrados projetos financiados.