Publicação
Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children
| Resumo: | Background/objectives Iodine deficiency disorders are estimated to affect 25% of all school-age children around the world. Current policies concerning iodine deficiency disorders in many countries are not based on robust or recent national data. Our objective was to evaluate the current status of iodine nutrition in Guinea-Bissau (West Africa).Subject/methods A cross-sectional survey including 299 school-age children, aged 6-14 years old, from four distinct regions of Guinea-Bissau across a coast-hinterland gradient (Bolama, Bissau, Cambaju-Bafata, and Gabil) was performed. Several iodine deficiency disorders indicators were used: total goiter rate, median urinary iodine concentration (UIC) and regional iodine content in household salt and drinking water samples. Data on the total goiter rate were obtained by thyroid ultrasound.Results Goiter was found in 73.5% (CI 95%, 68.5-78.2%) of the school-age children. We observed a median urinary iodine concentration of 110 mcg/l, with 7.3% of the studied population presenting urinary iodine concentration < 50 mcg/l. Only 12.5% of the household salt samples revealed iodine content >= 15 mg/kg. Median well water iodine concentration was 11.7 mcg/l.Conclusions Guinea-Bissau presents high rates of goiter in school-age children despite satisfactory median urinary iodine concentration population levels. Salt and drinking water iodine median content cannot explain these findings. Further studies following the progress in iodine deficiency status and the presence of potential goitrogens in diet of this vulnerable population are in needed. |
|---|---|
| Autores principais: | Carvalho, Andre Couto |
| Outros Autores: | Machado, Ana; Embalo, Adulai Robalo; Bordalo, Adriano A |
| Ano: | 2018 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1877775306223255552 |
|---|---|
| author | Carvalho, Andre Couto |
| author2 | Machado, Ana Embalo, Adulai Robalo Bordalo, Adriano A |
| author2_role | author author author |
| author_facet | Carvalho, Andre Couto Machado, Ana Embalo, Adulai Robalo Bordalo, Adriano A |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Carvalho, Andre Couto\"},{\"Person.name\":\"Machado, Ana\"},{\"Person.name\":\"Embalo, Adulai Robalo\"},{\"Person.name\":\"Bordalo, Adriano A\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Carvalho, Andre Couto Machado, Ana Embalo, Adulai Robalo Bordalo, Adriano A |
| datacite.date.Accepted.fl_str_mv | 2018-01-01T00:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.titles.title.fl_str_mv | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Carvalho, Andre Couto Machado, Ana Embalo, Adulai Robalo Bordalo, Adriano A |
| dc.date.Accepted.fl_str_mv | 2018-01-01T00:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/57792 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Nature Publishing Group |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.title.fl_str_mv | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Background/objectives Iodine deficiency disorders are estimated to affect 25% of all school-age children around the world. Current policies concerning iodine deficiency disorders in many countries are not based on robust or recent national data. Our objective was to evaluate the current status of iodine nutrition in Guinea-Bissau (West Africa).Subject/methods A cross-sectional survey including 299 school-age children, aged 6-14 years old, from four distinct regions of Guinea-Bissau across a coast-hinterland gradient (Bolama, Bissau, Cambaju-Bafata, and Gabil) was performed. Several iodine deficiency disorders indicators were used: total goiter rate, median urinary iodine concentration (UIC) and regional iodine content in household salt and drinking water samples. Data on the total goiter rate were obtained by thyroid ultrasound.Results Goiter was found in 73.5% (CI 95%, 68.5-78.2%) of the school-age children. We observed a median urinary iodine concentration of 110 mcg/l, with 7.3% of the studied population presenting urinary iodine concentration < 50 mcg/l. Only 12.5% of the household salt samples revealed iodine content >= 15 mg/kg. Median well water iodine concentration was 11.7 mcg/l.Conclusions Guinea-Bissau presents high rates of goiter in school-age children despite satisfactory median urinary iodine concentration population levels. Salt and drinking water iodine median content cannot explain these findings. Further studies following the progress in iodine deficiency status and the presence of potential goitrogens in diet of this vulnerable population are in needed. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | rum_9b53dd6fa99ea154f0ef506d33c9fba2 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/57792 |
| inst_facet_str | urn:organizationAcronym:repositorium{{{_:::_}}}Universidade do Minho |
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| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
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| oai_identifier_str | oai:repositorium.uminho.pt:1822/57792 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Carvalho, Andre Couto Machado, Ana Embalo, Adulai Robalo Bordalo, Adriano A |
| publishDate | 2018 |
| publisher.none.fl_str_mv | Nature Publishing Group |
| repo_facet_str | urn:repositoryAcronym:rum{{{_:::_}}}RepositóriUM - Universidade do Minho |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engNature Publishing GroupporBackground/objectives Iodine deficiency disorders are estimated to affect 25% of all school-age children around the world. Current policies concerning iodine deficiency disorders in many countries are not based on robust or recent national data. Our objective was to evaluate the current status of iodine nutrition in Guinea-Bissau (West Africa).Subject/methods A cross-sectional survey including 299 school-age children, aged 6-14 years old, from four distinct regions of Guinea-Bissau across a coast-hinterland gradient (Bolama, Bissau, Cambaju-Bafata, and Gabil) was performed. Several iodine deficiency disorders indicators were used: total goiter rate, median urinary iodine concentration (UIC) and regional iodine content in household salt and drinking water samples. Data on the total goiter rate were obtained by thyroid ultrasound.Results Goiter was found in 73.5% (CI 95%, 68.5-78.2%) of the school-age children. We observed a median urinary iodine concentration of 110 mcg/l, with 7.3% of the studied population presenting urinary iodine concentration < 50 mcg/l. Only 12.5% of the household salt samples revealed iodine content >= 15 mg/kg. Median well water iodine concentration was 11.7 mcg/l.Conclusions Guinea-Bissau presents high rates of goiter in school-age children despite satisfactory median urinary iodine concentration population levels. Salt and drinking water iodine median content cannot explain these findings. Further studies following the progress in iodine deficiency status and the presence of potential goitrogens in diet of this vulnerable population are in needed.application/pdfporEndemic goiter and iodine deficiency status among Guinea-Bissau school-age childrenCarvalho, Andre CoutoMachado, AnaEmbalo, Adulai RobaloBordalo, Adriano AHostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptPMID29284787ISSNIsPartOf0954-3007EISSNIsPartOf1476-5640DOIIsPartOf10.1038/s41430-017-0055-020182018-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/57792http://purl.org/coar/access_right/c_abf2open access541739 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdfhttps://repositorium.uminho.pt/bitstreams/2e16f3a3-513d-4aa9-9c96-f35b845c9bca/download |
| spellingShingle | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children Carvalho, Andre Couto |
| status | SINGLETON |
| title | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| title_full | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| title_fullStr | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| title_full_unstemmed | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| title_short | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| title_sort | Endemic goiter and iodine deficiency status among Guinea-Bissau school-age children |
| url | https://hdl.handle.net/1822/57792 |
| visible | 1 |
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