Publicação
Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications
| Resumo: | Poly (vinylidene fluoride) (PVDF) composites with different types of nanodiamond (ND) particles were produced by solvent casting. The variations of the morphological, structural, optical, thermal and electrical properties of the composites were studied as a function of nanofiller type (without and with air oxidation treatment) and concentration (in the range 0.11 wt%). No noticeable differences were found in the polymer crystallization process, the processing conditions and the filler determining the morphology and structure of the polymer. Nevertheless, ND nanofillers were useful for the tailoring of the optical properties, and also slightly contributed to the thermodynamic stability of the samples. An increase in the dielectric constant (2) of the ND composites, while maintaining constant the dielectric losses, was observed, independently of the filler concentration. On the other hand, solvent casted porous composites crystallize mainly in the electroactive -phase of PVDF. Those composite membranes were evaluated with pre-osteoblast culture tests and these revealed that the inclusion of ND nanoparticles does not induce cytotoxicity on the samples. Taking advantage of the properties of the polymer for cell culture and with the potential of the ND filler for protein functionalization and drug delivery, it is concluded that NDs/PVDF composites are a suitable platform for biomedical applications. |
|---|---|
| Autores principais: | Pereira, Eduardo Jorge Nunes |
| Outros Autores: | Silva, A. R.; Ribeiro, Clarisse; Carabineiro, S. A. C.; Buijnsters, J. G.; Lanceros-Méndez, S. |
| Assunto: | Nanodiamonds poly(vinylidene fluoride) Cell culture |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1877776638745247744 |
|---|---|
| author | Pereira, Eduardo Jorge Nunes |
| author2 | Silva, A. R. Ribeiro, Clarisse Carabineiro, S. A. C. Buijnsters, J. G. Lanceros-Méndez, S. |
| author2_role | author author author author author |
| author_facet | Pereira, Eduardo Jorge Nunes Silva, A. R. Ribeiro, Clarisse Carabineiro, S. A. C. Buijnsters, J. G. Lanceros-Méndez, S. |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Pereira, Eduardo Jorge Nunes\"},{\"Person.name\":\"Silva, A. R.\"},{\"Person.name\":\"Ribeiro, Clarisse\"},{\"Person.name\":\"Carabineiro, S. A. C.\"},{\"Person.name\":\"Buijnsters, J. G.\"},{\"Person.name\":\"Lanceros-Méndez, S.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Pereira, Eduardo Jorge Nunes Silva, A. R. Ribeiro, Clarisse Carabineiro, S. A. C. Buijnsters, J. G. Lanceros-Méndez, S. |
| datacite.date.Accepted.fl_str_mv | 2017-02-15T00:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| datacite.subjects.subject.fl_str_mv | Nanodiamonds poly(vinylidene fluoride) Cell culture |
| datacite.titles.title.fl_str_mv | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Pereira, Eduardo Jorge Nunes Silva, A. R. Ribeiro, Clarisse Carabineiro, S. A. C. Buijnsters, J. G. Lanceros-Méndez, S. |
| dc.date.Accepted.fl_str_mv | 2017-02-15T00:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/43875 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| dc.subject.none.fl_str_mv | Nanodiamonds poly(vinylidene fluoride) Cell culture |
| dc.title.fl_str_mv | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Poly (vinylidene fluoride) (PVDF) composites with different types of nanodiamond (ND) particles were produced by solvent casting. The variations of the morphological, structural, optical, thermal and electrical properties of the composites were studied as a function of nanofiller type (without and with air oxidation treatment) and concentration (in the range 0.11 wt%). No noticeable differences were found in the polymer crystallization process, the processing conditions and the filler determining the morphology and structure of the polymer. Nevertheless, ND nanofillers were useful for the tailoring of the optical properties, and also slightly contributed to the thermodynamic stability of the samples. An increase in the dielectric constant (2) of the ND composites, while maintaining constant the dielectric losses, was observed, independently of the filler concentration. On the other hand, solvent casted porous composites crystallize mainly in the electroactive -phase of PVDF. Those composite membranes were evaluated with pre-osteoblast culture tests and these revealed that the inclusion of ND nanoparticles does not induce cytotoxicity on the samples. Taking advantage of the properties of the polymer for cell culture and with the potential of the ND filler for protein functionalization and drug delivery, it is concluded that NDs/PVDF composites are a suitable platform for biomedical applications. |
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| eu_rights_str_mv | restrictedAccess |
| format | article |
| id | rum_2783dc4710865cf5b8e533bd5547d79d |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/43875 |
| inst_facet_str | urn:organizationAcronym:repositorium{{{_:::_}}}Universidade do Minho |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/43875 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Pereira, Eduardo Jorge Nunes Silva, A. R. Ribeiro, Clarisse Carabineiro, S. A. C. Buijnsters, J. G. Lanceros-Méndez, S. |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Elsevier |
| repo_facet_str | urn:repositoryAcronym:rum{{{_:::_}}}RepositóriUM - Universidade do Minho |
| reponame_str | RepositóriUM - Universidade do Minho |
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| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engElsevierporPoly (vinylidene fluoride) (PVDF) composites with different types of nanodiamond (ND) particles were produced by solvent casting. The variations of the morphological, structural, optical, thermal and electrical properties of the composites were studied as a function of nanofiller type (without and with air oxidation treatment) and concentration (in the range 0.11 wt%). No noticeable differences were found in the polymer crystallization process, the processing conditions and the filler determining the morphology and structure of the polymer. Nevertheless, ND nanofillers were useful for the tailoring of the optical properties, and also slightly contributed to the thermodynamic stability of the samples. An increase in the dielectric constant (2) of the ND composites, while maintaining constant the dielectric losses, was observed, independently of the filler concentration. On the other hand, solvent casted porous composites crystallize mainly in the electroactive -phase of PVDF. Those composite membranes were evaluated with pre-osteoblast culture tests and these revealed that the inclusion of ND nanoparticles does not induce cytotoxicity on the samples. Taking advantage of the properties of the polymer for cell culture and with the potential of the ND filler for protein functionalization and drug delivery, it is concluded that NDs/PVDF composites are a suitable platform for biomedical applications.application/pdfporNanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applicationsPereira, Eduardo Jorge NunesSilva, A. R.Ribeiro, ClarisseCarabineiro, S. A. C.Buijnsters, J. G.Lanceros-Méndez, S.HostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptCITATIONJ. Nunes-Pereira; Silva, A. R.; Ribeiro, Clarisse; Carabineiro, S. A. C.; Buijnsters, J. G.; Lanceros-Méndez, S., Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications. Composites Part B: Engineering, 111, 37-44, 2017. doi: 10.1016/j.compositesb.2016.12.014ISSNIsPartOf1359-8368DOIIsPartOf10.1016/j.compositesb.2016.12.0142017-02-152017-02-15T00:00:00ZHandlehttps://hdl.handle.net/1822/43875http://purl.org/coar/access_right/c_16ecrestricted accessNanodiamondspoly(vinylidene fluoride)Cell culture1082419 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdfhttps://repositorium.uminho.pt/bitstreams/da8811b9-6e49-45c9-8910-9c0f06443a27/download |
| spellingShingle | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications Pereira, Eduardo Jorge Nunes Nanodiamonds poly(vinylidene fluoride) Cell culture |
| status | SINGLETON |
| subject.fl_str_mv | Nanodiamonds poly(vinylidene fluoride) Cell culture |
| title | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| title_full | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| title_fullStr | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| title_full_unstemmed | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| title_short | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| title_sort | Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications |
| topic | Nanodiamonds poly(vinylidene fluoride) Cell culture |
| topic_facet | Nanodiamonds poly(vinylidene fluoride) Cell culture |
| url | https://hdl.handle.net/1822/43875 |
| visible | 1 |
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