Publicação
FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE
| Resumo: | The immune response of three different formulations of foot-and-mouth disease (FMD) oil vaccines in vaccinated cattle was compared. The vaccines used were: 1) standard oil vaccine (VOR) without aluminum hydroxide; 2) VOR with aluminum hydroxide (VOAI) and 3) oil vaccine containing antigen 10x concentrated by aluminum hydroxide (V010x). Each vaccine was used in a group of 9 animais, and each animal received a 5m1 dose of vaccine by intramuscular rouco. Neutralizing antibodies were evaluated by vírus neutralization test (VN) at day 0 and at 30, 90 and 180 days post vaccination. All animais were shown previously to be free of either neutralizing or anti-VIA (vira) infection associated antigen) antibodies and were considered to be susceptible to FMD. Serology for anti-VIA antibodies was carried out and the tests were negativo during the experiment. The results obtained showed that concentrating antigen (10x) was not enough to increase significantly (P>0.05) the leveis of neutralizing antibodies, and also that the aluminum hydroxide (HAI) included in VOR did not increase significantly the levei of these antibodies. Antigen concentration (10x) plus the addition of HAI increased significantly (P<0.05) the antibody levels of vaccinated animais. |
|---|---|
| Autores principais: | PETZHOLD, SYLIO ALFREDO |
| Outros Autores: | PIRES PRADO, JOSÉ ANTÔNIO; RECKZIEGEL, PAULO ESTANISLÁO; FREITAS TEIXEIRA, JOÃO CARLOS; WALD, VERA BEATRIZ |
| Assunto: | Immunology. Cattle vaccines. Foot-and-mouth disease. Aluminum hydroxide. Oil vaccines. Imunologia. Vacina bovino. Aftosa. Hidróxido de alumínio. Vacina oleosa. |
| Ano: | 1996 |
| País: | Brasil |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | IBICT |
| Idioma: | português |
| Origem: | Oasisbr |
| _version_ | 1871512758981230592 |
|---|---|
| author | PETZHOLD, SYLIO ALFREDO |
| author2 | PIRES PRADO, JOSÉ ANTÔNIO RECKZIEGEL, PAULO ESTANISLÁO FREITAS TEIXEIRA, JOÃO CARLOS WALD, VERA BEATRIZ |
| author2_role | author author author author |
| author_facet | PETZHOLD, SYLIO ALFREDO PIRES PRADO, JOSÉ ANTÔNIO RECKZIEGEL, PAULO ESTANISLÁO FREITAS TEIXEIRA, JOÃO CARLOS WALD, VERA BEATRIZ |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"PETZHOLD, SYLIO ALFREDO\"},{\"Person.name\":\"PIRES PRADO, JOSÉ ANTÔNIO\"},{\"Person.name\":\"RECKZIEGEL, PAULO ESTANISLÁO\"},{\"Person.name\":\"FREITAS TEIXEIRA, JOÃO CARLOS\"},{\"Person.name\":\"WALD, VERA BEATRIZ\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | PETZHOLD, SYLIO ALFREDO PIRES PRADO, JOSÉ ANTÔNIO RECKZIEGEL, PAULO ESTANISLÁO FREITAS TEIXEIRA, JOÃO CARLOS WALD, VERA BEATRIZ |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Immunology. Cattle vaccines. Foot-and-mouth disease. Aluminum hydroxide. Oil vaccines. Imunologia. Vacina bovino. Aftosa. Hidróxido de alumínio. Vacina oleosa. |
| datacite.titles.title.fl_str_mv | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE VACINAS ANTIAFTOSA OLEOSAS COM E SEM ANTÍGENOS CONCENTRADOS POR HIDRÓXIDO DE ALUMÍNIO: RESPOSTA IMUNE DE BOVINOS PRIMOVACINADOS |
| dc.creator.none.fl_str_mv | PETZHOLD, SYLIO ALFREDO PIRES PRADO, JOSÉ ANTÔNIO RECKZIEGEL, PAULO ESTANISLÁO FREITAS TEIXEIRA, JOÃO CARLOS WALD, VERA BEATRIZ |
| dc.description.none.fl_str_mv | A resposta imune, induzida por três diferentes vacinas antiaftosa oleosas, foi comparada em bovinos primovacinados. As vacinas utilizadas foram: 1) vacina oleosa referência (VOR) sem hidróxido de alumínio; 2) VOR com hidróxido de alumínio (VOAI) e 3) vacina oleosa com antígeno 10 vezes concentrado por hidróxido de alumínio (VOI0x). Cada vacina experimental foi aplicada em um grupo de 9 bovinos, recebendo cada animal a dose de 5 ml por via intramuscular. Os anticorpos neutralizantes induzidos pelas vacinas foram quantificados ao zero dia, e aos 30, 90 e 180 dias pós-vacinação através de testes de vírusneutralização (VN).. Todos os animais foram testados previamente por VN e pára a presença de anticorpos contra antígenos associados à infecção virai (VIA), sendo considerados sensíveis à febre aftosa e permanecendo VIA negativos por todo o período do experimento. Os resultados obtidos revelaram que, isoladamente, a concentração do antígeno 10 vezes ou a adição de hiróxido de alumínio (HAI), não foram suficientes para incrementar significativamente (P>0,05) os índices de anticorpos neutralizantes. A concentração do antígeno 10 vezes e a concomitante adição de HA1 estimularam significativamente (P<0,05) os níveis de anticorpos circulantes detectados. |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://revistapag.agricultura.rs.gov.br/ojs/index.php/revistapag/article/view/608 |
| dc.language.none.fl_str_mv | por |
| dc.publisher.none.fl_str_mv | Departamento de Diagnóstico e Pesquisa Agropecuária. Secretaria de Agricultura, Pecuária e Desenvolvimento Rural |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Pesquisa Agropecuária Gaúcha; Vol 2 No 1 (1996): PESQ. AGROP. GAÚCHA; 111-118 Pesquisa Agropecuária Gaúcha; v. 2 n. 1 (1996): PESQ. AGROP. GAÚCHA; 111-118 2595-7686 0104-9070 reponame:Pesquisa Agropecuária Gaúcha (Online) instname:Secretaria de Agricultura, Pecuária e Desenvolvimento Rural do Rio Grande do Sul instacron:SEAPDR |
| dc.subject.none.fl_str_mv | Immunology. Cattle vaccines. Foot-and-mouth disease. Aluminum hydroxide. Oil vaccines. Imunologia. Vacina bovino. Aftosa. Hidróxido de alumínio. Vacina oleosa. |
| dc.title.fl_str_mv | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE VACINAS ANTIAFTOSA OLEOSAS COM E SEM ANTÍGENOS CONCENTRADOS POR HIDRÓXIDO DE ALUMÍNIO: RESPOSTA IMUNE DE BOVINOS PRIMOVACINADOS |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | The immune response of three different formulations of foot-and-mouth disease (FMD) oil vaccines in vaccinated cattle was compared. The vaccines used were: 1) standard oil vaccine (VOR) without aluminum hydroxide; 2) VOR with aluminum hydroxide (VOAI) and 3) oil vaccine containing antigen 10x concentrated by aluminum hydroxide (V010x). Each vaccine was used in a group of 9 animais, and each animal received a 5m1 dose of vaccine by intramuscular rouco. Neutralizing antibodies were evaluated by vírus neutralization test (VN) at day 0 and at 30, 90 and 180 days post vaccination. All animais were shown previously to be free of either neutralizing or anti-VIA (vira) infection associated antigen) antibodies and were considered to be susceptible to FMD. Serology for anti-VIA antibodies was carried out and the tests were negativo during the experiment. The results obtained showed that concentrating antigen (10x) was not enough to increase significantly (P>0.05) the leveis of neutralizing antibodies, and also that the aluminum hydroxide (HAI) included in VOR did not increase significantly the levei of these antibodies. Antigen concentration (10x) plus the addition of HAI increased significantly (P<0.05) the antibody levels of vaccinated animais. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | oasisbr_ff2c4cccd4c19ccff6d2b9c46690f363 |
| identifier.url.fl_str_mv | http://revistapag.agricultura.rs.gov.br/ojs/index.php/revistapag/article/view/608 |
| inst_facet_str | urn:organizationAcronym:oasisbr{{{_:::_}}}IBICT |
| instacron_str | OASISBR |
| institution | IBICT |
| instname_str | IBICT |
| language | por |
| network_acronym_str | oasisbr |
| network_name_str | Oasisbr |
| oai_identifier_str | oai:ojs.revistapag.agricultura.rs.gov.br:article/608 |
| organization_str_mv | urn:organizationAcronym:oasisbr |
| person_str_mv | PETZHOLD, SYLIO ALFREDO PIRES PRADO, JOSÉ ANTÔNIO RECKZIEGEL, PAULO ESTANISLÁO FREITAS TEIXEIRA, JOÃO CARLOS WALD, VERA BEATRIZ |
| publishDate | 1996 |
| publisher.none.fl_str_mv | Departamento de Diagnóstico e Pesquisa Agropecuária. Secretaria de Agricultura, Pecuária e Desenvolvimento Rural |
| repo_facet_str | urn:repositoryAcronym:oasisbr{{{_:::_}}}Oasisbr |
| reponame_str | Oasisbr |
| repository_id_str | urn:repositoryAcronym:oasisbr |
| service_str_mv | urn:repositoryAcronym:oasisbr |
| spelling | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLEVACINAS ANTIAFTOSA OLEOSAS COM E SEM ANTÍGENOS CONCENTRADOS POR HIDRÓXIDO DE ALUMÍNIO: RESPOSTA IMUNE DE BOVINOS PRIMOVACINADOSPETZHOLD, SYLIO ALFREDOPIRES PRADO, JOSÉ ANTÔNIORECKZIEGEL, PAULO ESTANISLÁOFREITAS TEIXEIRA, JOÃO CARLOSWALD, VERA BEATRIZImmunology.Cattle vaccines.Foot-and-mouth disease.Aluminum hydroxide.Oil vaccines.Imunologia.Vacina bovino.Aftosa.Hidróxido de alumínio.Vacina oleosa.open accesshttp://purl.org/coar/access_right/c_abf2http://revistapag.agricultura.rs.gov.br/ojs/index.php/revistapag/article/view/608URLhttp://revistapag.agricultura.rs.gov.br/ojs/index.php/revistapag/article/view/608URLHasVersionhttp://revistapag.agricultura.rs.gov.br/ojs/index.php/revistapag/article/view/608/558URLHasVersion1996-01-26 The immune response of three different formulations of foot-and-mouth disease (FMD) oil vaccines in vaccinated cattle was compared. The vaccines used were: 1) standard oil vaccine (VOR) without aluminum hydroxide; 2) VOR with aluminum hydroxide (VOAI) and 3) oil vaccine containing antigen 10x concentrated by aluminum hydroxide (V010x). Each vaccine was used in a group of 9 animais, and each animal received a 5m1 dose of vaccine by intramuscular rouco. Neutralizing antibodies were evaluated by vírus neutralization test (VN) at day 0 and at 30, 90 and 180 days post vaccination. All animais were shown previously to be free of either neutralizing or anti-VIA (vira) infection associated antigen) antibodies and were considered to be susceptible to FMD. Serology for anti-VIA antibodies was carried out and the tests were negativo during the experiment. The results obtained showed that concentrating antigen (10x) was not enough to increase significantly (P>0.05) the leveis of neutralizing antibodies, and also that the aluminum hydroxide (HAI) included in VOR did not increase significantly the levei of these antibodies. Antigen concentration (10x) plus the addition of HAI increased significantly (P<0.05) the antibody levels of vaccinated animais.A resposta imune, induzida por três diferentes vacinas antiaftosa oleosas, foi comparada em bovinos primovacinados. As vacinas utilizadas foram: 1) vacina oleosa referência (VOR) sem hidróxido de alumínio; 2) VOR com hidróxido de alumínio (VOAI) e 3) vacina oleosa com antígeno 10 vezes concentrado por hidróxido de alumínio (VOI0x). Cada vacina experimental foi aplicada em um grupo de 9 bovinos, recebendo cada animal a dose de 5 ml por via intramuscular. Os anticorpos neutralizantes induzidos pelas vacinas foram quantificados ao zero dia, e aos 30, 90 e 180 dias pós-vacinação através de testes de vírusneutralização (VN).. Todos os animais foram testados previamente por VN e pára a presença de anticorpos contra antígenos associados à infecção virai (VIA), sendo considerados sensíveis à febre aftosa e permanecendo VIA negativos por todo o período do experimento. Os resultados obtidos revelaram que, isoladamente, a concentração do antígeno 10 vezes ou a adição de hiróxido de alumínio (HAI), não foram suficientes para incrementar significativamente (P>0,05) os índices de anticorpos neutralizantes. A concentração do antígeno 10 vezes e a concomitante adição de HA1 estimularam significativamente (P<0,05) os níveis de anticorpos circulantes detectados.porapplication/pdfDepartamento de Diagnóstico e Pesquisa Agropecuária. Secretaria de Agricultura, Pecuária e Desenvolvimento RuralPesquisa Agropecuária Gaúcha; Vol 2 No 1 (1996): PESQ. AGROP. GAÚCHA; 111-118Pesquisa Agropecuária Gaúcha; v. 2 n. 1 (1996): PESQ. AGROP. GAÚCHA; 111-1182595-76860104-9070reponame:Pesquisa Agropecuária Gaúcha (Online)instname:Secretaria de Agricultura, Pecuária e Desenvolvimento Rural do Rio Grande do Sulinstacron:SEAPDRjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE PETZHOLD, SYLIO ALFREDO Immunology. Cattle vaccines. Foot-and-mouth disease. Aluminum hydroxide. Oil vaccines. Imunologia. Vacina bovino. Aftosa. Hidróxido de alumínio. Vacina oleosa. |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | Immunology. Cattle vaccines. Foot-and-mouth disease. Aluminum hydroxide. Oil vaccines. Imunologia. Vacina bovino. Aftosa. Hidróxido de alumínio. Vacina oleosa. |
| title | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE |
| title_full | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE |
| title_fullStr | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE |
| title_full_unstemmed | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE |
| title_short | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE |
| title_sort | FOOT-AND-MOUTH DISEASE OIL VACCINES WITH OR WITHOUT ALUMINUM HYDROXIDE CONCENTRATION OF ANTIGEN: IMMUNE RESPONSE IN VACCINATED CATTLE |
| topic | Immunology. Cattle vaccines. Foot-and-mouth disease. Aluminum hydroxide. Oil vaccines. Imunologia. Vacina bovino. Aftosa. Hidróxido de alumínio. Vacina oleosa. |
| topic_facet | Immunology. Cattle vaccines. Foot-and-mouth disease. Aluminum hydroxide. Oil vaccines. Imunologia. Vacina bovino. Aftosa. Hidróxido de alumínio. Vacina oleosa. |
| url | http://revistapag.agricultura.rs.gov.br/ojs/index.php/revistapag/article/view/608 |
| visible | 1 |
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