Publicação
SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events
| Resumo: | Abstract Background: The SAMe-TT2R2 score was developed to predict which patients on oral anticoagulation with vitamin K antagonists (VKAs) will reach an adequate time in therapeutic range (TTR) (> 65%-70%). Studies have reported a relationship between this score and the occurrence of adverse events. Objective: To describe the TTR according to the score, in addition to relating the score obtained with the occurrence of adverse events in patients with nonvalvular atrial fibrillation (AF) on oral anticoagulation with VKAs. Methods: Retrospective cohort study including patients with nonvalvular AF attending an outpatient anticoagulation clinic of a tertiary hospital. Visits to the outpatient clinic and emergency, as well as hospital admissions to the institution, during 2014 were evaluated. The TTR was calculated through the Rosendaal´s method. Results: We analyzed 263 patients (median TTR, 62.5%). The low-risk group (score 0-1) had a better median TTR as compared with the high-risk group (score ≥ 2): 69.2% vs. 56.3%, p = 0.002. Similarly, the percentage of patients with TTR ≥ 60%, 65% or 70% was higher in the low-risk group (p < 0.001, p = 0.001 and p = 0.003, respectively). The high-risk group had a higher percentage of adverse events (11.2% vs. 7.2%), although not significant (p = 0.369). Conclusions: The SAMe-TT2R2 score proved to be effective to predict patients with a better TTR, but was not associated with adverse events. |
|---|---|
| Autores principais: | Pivatto Júnior,Fernando |
| Outros Autores: | Scheffel,Rafael Selbach; Ries,Lucas; Wolkind,Ricardo Roitman; Marobin,Roberta; Barkan,Sabrina Sigal; Amon,Luís Carlos; Biolo,Andréia |
| Assunto: | Atrial Fibrillation Anticoagulants / adverse effects Decision Support Techniques Warfarin Phenprocoumon Vitamin K |
| Ano: | 2017 |
| País: | Brasil |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | IBICT |
| Idioma: | inglês |
| Origem: | Oasisbr |
| _version_ | 1871507939461693440 |
|---|---|
| author | Pivatto Júnior,Fernando |
| author2 | Scheffel,Rafael Selbach Ries,Lucas Wolkind,Ricardo Roitman Marobin,Roberta Barkan,Sabrina Sigal Amon,Luís Carlos Biolo,Andréia |
| author2_role | author author author author author author author |
| author_facet | Pivatto Júnior,Fernando Scheffel,Rafael Selbach Ries,Lucas Wolkind,Ricardo Roitman Marobin,Roberta Barkan,Sabrina Sigal Amon,Luís Carlos Biolo,Andréia |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"Pivatto Júnior,Fernando\"},{\"Person.name\":\"Scheffel,Rafael Selbach\"},{\"Person.name\":\"Ries,Lucas\"},{\"Person.name\":\"Wolkind,Ricardo Roitman\"},{\"Person.name\":\"Marobin,Roberta\"},{\"Person.name\":\"Barkan,Sabrina Sigal\"},{\"Person.name\":\"Amon,Luís Carlos\"},{\"Person.name\":\"Biolo,Andréia\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Pivatto Júnior,Fernando Scheffel,Rafael Selbach Ries,Lucas Wolkind,Ricardo Roitman Marobin,Roberta Barkan,Sabrina Sigal Amon,Luís Carlos Biolo,Andréia |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Atrial Fibrillation Anticoagulants / adverse effects Decision Support Techniques Warfarin Phenprocoumon Vitamin K |
| datacite.titles.title.fl_str_mv | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| dc.creator.none.fl_str_mv | Pivatto Júnior,Fernando Scheffel,Rafael Selbach Ries,Lucas Wolkind,Ricardo Roitman Marobin,Roberta Barkan,Sabrina Sigal Amon,Luís Carlos Biolo,Andréia |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000400290 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Brasileira de Cardiologia - SBC |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Arquivos Brasileiros de Cardiologia v.108 n.4 2017 reponame:Arquivos Brasileiros de Cardiologia (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
| dc.subject.none.fl_str_mv | Atrial Fibrillation Anticoagulants / adverse effects Decision Support Techniques Warfarin Phenprocoumon Vitamin K |
| dc.title.fl_str_mv | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Abstract Background: The SAMe-TT2R2 score was developed to predict which patients on oral anticoagulation with vitamin K antagonists (VKAs) will reach an adequate time in therapeutic range (TTR) (> 65%-70%). Studies have reported a relationship between this score and the occurrence of adverse events. Objective: To describe the TTR according to the score, in addition to relating the score obtained with the occurrence of adverse events in patients with nonvalvular atrial fibrillation (AF) on oral anticoagulation with VKAs. Methods: Retrospective cohort study including patients with nonvalvular AF attending an outpatient anticoagulation clinic of a tertiary hospital. Visits to the outpatient clinic and emergency, as well as hospital admissions to the institution, during 2014 were evaluated. The TTR was calculated through the Rosendaal´s method. Results: We analyzed 263 patients (median TTR, 62.5%). The low-risk group (score 0-1) had a better median TTR as compared with the high-risk group (score ≥ 2): 69.2% vs. 56.3%, p = 0.002. Similarly, the percentage of patients with TTR ≥ 60%, 65% or 70% was higher in the low-risk group (p < 0.001, p = 0.001 and p = 0.003, respectively). The high-risk group had a higher percentage of adverse events (11.2% vs. 7.2%), although not significant (p = 0.369). Conclusions: The SAMe-TT2R2 score proved to be effective to predict patients with a better TTR, but was not associated with adverse events. |
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| identifier.url.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000400290 |
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| institution | IBICT |
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| language | eng |
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| person_str_mv | Pivatto Júnior,Fernando Scheffel,Rafael Selbach Ries,Lucas Wolkind,Ricardo Roitman Marobin,Roberta Barkan,Sabrina Sigal Amon,Luís Carlos Biolo,Andréia |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Sociedade Brasileira de Cardiologia - SBC |
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| spelling | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse EventsPivatto Júnior,FernandoScheffel,Rafael SelbachRies,LucasWolkind,Ricardo RoitmanMarobin,RobertaBarkan,Sabrina SigalAmon,Luís CarlosBiolo,AndréiaAtrial FibrillationAnticoagulants / adverse effectsDecision Support TechniquesWarfarinPhenprocoumonVitamin Kopen accesshttp://purl.org/coar/access_right/c_abf2http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000400290URLhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000400290URLHasVersion2017-04-01Abstract Background: The SAMe-TT2R2 score was developed to predict which patients on oral anticoagulation with vitamin K antagonists (VKAs) will reach an adequate time in therapeutic range (TTR) (> 65%-70%). Studies have reported a relationship between this score and the occurrence of adverse events. Objective: To describe the TTR according to the score, in addition to relating the score obtained with the occurrence of adverse events in patients with nonvalvular atrial fibrillation (AF) on oral anticoagulation with VKAs. Methods: Retrospective cohort study including patients with nonvalvular AF attending an outpatient anticoagulation clinic of a tertiary hospital. Visits to the outpatient clinic and emergency, as well as hospital admissions to the institution, during 2014 were evaluated. The TTR was calculated through the Rosendaal´s method. Results: We analyzed 263 patients (median TTR, 62.5%). The low-risk group (score 0-1) had a better median TTR as compared with the high-risk group (score ≥ 2): 69.2% vs. 56.3%, p = 0.002. Similarly, the percentage of patients with TTR ≥ 60%, 65% or 70% was higher in the low-risk group (p < 0.001, p = 0.001 and p = 0.003, respectively). The high-risk group had a higher percentage of adverse events (11.2% vs. 7.2%), although not significant (p = 0.369). Conclusions: The SAMe-TT2R2 score proved to be effective to predict patients with a better TTR, but was not associated with adverse events.engtext/htmlSociedade Brasileira de Cardiologia - SBCArquivos Brasileiros de Cardiologia v.108 n.4 2017reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBCjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events Pivatto Júnior,Fernando Atrial Fibrillation Anticoagulants / adverse effects Decision Support Techniques Warfarin Phenprocoumon Vitamin K |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | Atrial Fibrillation Anticoagulants / adverse effects Decision Support Techniques Warfarin Phenprocoumon Vitamin K |
| title | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| title_full | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| title_fullStr | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| title_full_unstemmed | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| title_short | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| title_sort | SAMe-TT2R2 Score in the Outpatient Anticoagulation Clinic to Predict Time in Therapeutic Range and Adverse Events |
| topic | Atrial Fibrillation Anticoagulants / adverse effects Decision Support Techniques Warfarin Phenprocoumon Vitamin K |
| topic_facet | Atrial Fibrillation Anticoagulants / adverse effects Decision Support Techniques Warfarin Phenprocoumon Vitamin K |
| url | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2017000400290 |
| visible | 1 |
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