Publication

Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning

View document

Bibliographic Details
Summary:Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an external electric field to create fiber from the polymeric jet solution. This article investigates both processes using two different biocompatible polymers: Poly(L-lactic acid) (PLLA) and Poly(ε-caprolactone) (PCL). Samples were characterized by scanning electron microscopy, thermogravimetric analysis, differential scanning calorimeter, and Fourier-transform infrared spectroscopy. Morphological observations showed the efficiency of both techniques in obtaining nanofibers. Thermal analyses of data indicate immiscible property of different blends and the total solvent evaporation. In vitro cytocompatibility test showed that RJS and electrospinning samples exhibited good cytocompatibility. Based on these results, it may be concluded that the fibers obtained with both technologies are non-cytotoxicity and with good biocompatibility, and might be suitable for applications as scaffold for cell growth.
Main Authors:Vida,Talita Almeida
Other Authors:Motta,Adriana Cristina; Santos Jr.,Arnaldo Rodrigues; Cardoso,Guinea Brasil Camargo; Brito,Crystopher Cardoso de; Zavaglia,Cecília Amélia de Carvalho
Subject:Rotary jet spinning Electrospinning Blend Nanofibers Biomaterials
Year:2017
Country:Brazil
Document type:article
Access type:open access
Associated institution:IBICT
Language:English
Origin:Oasisbr

Similar Items

Funded activities

No funded projects found.

Similar Items