Publication
Bacterial cellulose/collagen hydrogel for wound healing
| Summary: | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) |
|---|---|
| Main Authors: | De Sousa Moraes, Paula Rodrigues Fontes |
| Other Authors: | Saska, Sybele; Barud, Hernane; De Lima, Lais Roncalho; Da Conceicao Amaro Martins, Virginia; De Guzzi Plepis, Ana Maria; Ribeiro, Sidney Jose Lima; Gaspar, Ana Maria Minarelli |
| Subject: | Bacterial cellulose Collagen Hydrogel Tissue repair Wound dressing |
| Year: | 2018 |
| Country: | Brazil |
| Document type: | article |
| Access type: | open access |
| Associated institution: | IBICT |
| Language: | English |
| Origin: | Oasisbr |
| _version_ | 1871568697487785984 |
|---|---|
| author | De Sousa Moraes, Paula Rodrigues Fontes |
| author2 | Saska, Sybele Barud, Hernane De Lima, Lais Roncalho Da Conceicao Amaro Martins, Virginia De Guzzi Plepis, Ana Maria Ribeiro, Sidney Jose Lima Gaspar, Ana Maria Minarelli |
| author2_role | author author author author author author author |
| author_facet | De Sousa Moraes, Paula Rodrigues Fontes Saska, Sybele Barud, Hernane De Lima, Lais Roncalho Da Conceicao Amaro Martins, Virginia De Guzzi Plepis, Ana Maria Ribeiro, Sidney Jose Lima Gaspar, Ana Maria Minarelli |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"De Sousa Moraes, Paula Rodrigues Fontes\"},{\"Person.name\":\"Saska, Sybele\"},{\"Person.name\":\"Barud, Hernane\"},{\"Person.name\":\"De Lima, Lais Roncalho\"},{\"Person.name\":\"Da Conceicao Amaro Martins, Virginia\"},{\"Person.name\":\"De Guzzi Plepis, Ana Maria\"},{\"Person.name\":\"Ribeiro, Sidney Jose Lima\"},{\"Person.name\":\"Gaspar, Ana Maria Minarelli\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | De Sousa Moraes, Paula Rodrigues Fontes Saska, Sybele Barud, Hernane De Lima, Lais Roncalho Da Conceicao Amaro Martins, Virginia De Guzzi Plepis, Ana Maria Ribeiro, Sidney Jose Lima Gaspar, Ana Maria Minarelli |
| datacite.date.Accepted.fl_str_mv | 2016-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2018-12-11T17:23:05Z |
| datacite.date.embargoed.fl_str_mv | 2018-12-11T17:23:05Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Bacterial cellulose Collagen Hydrogel Tissue repair Wound dressing |
| datacite.titles.title.fl_str_mv | Bacterial cellulose/collagen hydrogel for wound healing |
| dc.creator.none.fl_str_mv | De Sousa Moraes, Paula Rodrigues Fontes Saska, Sybele Barud, Hernane De Lima, Lais Roncalho Da Conceicao Amaro Martins, Virginia De Guzzi Plepis, Ana Maria Ribeiro, Sidney Jose Lima Gaspar, Ana Maria Minarelli |
| dc.date.Accepted.fl_str_mv | 2016-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2018-12-11T17:23:05Z |
| dc.date.embargoed.fl_str_mv | 2018-12-11T17:23:05Z |
| dc.description.none.fl_str_mv | This study compares a wound dressing based on bacterial cellulose/collagen (BC/COL) hydrogel in rat dorsum with commercial collagenase ointment and untreated wound. The hydrogel was characterized by Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier transformed-Infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). According to the In vivo test and macroscopic evaluation, BC/COL hydrogel showed a better repair of wounds and promoted statistically significant differences of tissue repair between treatments on the 7th day after surgery. Better quality, quantity and orientation evaluation of collagen fibers (p=0.0001) were observed in the BC/COL hydrogel and collagenase ointment groups in relation to the control group. The BC/COL hydrogel promoted better wound healing than collagenase and the control group, therefore, it can be considered a potential wound dressing for skin regeneration. |
| dc.format.none.fl_str_mv | 106-116 |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/11449/176915 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
| dc.subject.none.fl_str_mv | Bacterial cellulose Collagen Hydrogel Tissue repair Wound dressing |
| dc.title.fl_str_mv | Bacterial cellulose/collagen hydrogel for wound healing |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | oasisbr_b9604b204ef19e9f461c045a67aa09e8 |
| identifier.url.fl_str_mv | http://hdl.handle.net/11449/176915 |
| inst_facet_str | urn:organizationAcronym:oasisbr{{{_:::_}}}IBICT |
| instacron_str | OASISBR |
| institution | IBICT |
| instname_str | IBICT |
| language | eng |
| network_acronym_str | oasisbr |
| network_name_str | Oasisbr |
| oai_identifier_str | oai:repositorio.unesp.br:11449/176915 |
| organization_str_mv | urn:organizationAcronym:oasisbr |
| person_str_mv | De Sousa Moraes, Paula Rodrigues Fontes Saska, Sybele Barud, Hernane De Lima, Lais Roncalho Da Conceicao Amaro Martins, Virginia De Guzzi Plepis, Ana Maria Ribeiro, Sidney Jose Lima Gaspar, Ana Maria Minarelli |
| publishDate | 2018 |
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| reponame_str | Oasisbr |
| repository_id_str | urn:repositoryAcronym:oasisbr |
| service_str_mv | urn:repositoryAcronym:oasisbr |
| spelling | Bacterial cellulose/collagen hydrogel for wound healingDe Sousa Moraes, Paula Rodrigues FontesSaska, SybeleBarud, HernaneDe Lima, Lais RoncalhoDa Conceicao Amaro Martins, VirginiaDe Guzzi Plepis, Ana MariaRibeiro, Sidney Jose LimaGaspar, Ana Maria MinarelliBacterial celluloseCollagenHydrogelTissue repairWound dressingopen accesshttp://purl.org/coar/access_right/c_abf2http://hdl.handle.net/11449/176915HandleMaterials Research, v. 19, n. 1, p. 106-116, 2016.N/AHasVersion1516-1439N/AHasVersionS1516-14392016000100106N/AHasVersion2-s2.0-84963541542N/AHasVersionS1516-14392016000100106.pdfN/AHasVersionhttps://doi.org/http://dx.doi.org/10.1590/1980-5373-MR-2015-0249DOIhttp://hdl.handle.net/11449/176915Handlehttps://doi.org/10.1590/1980-5373-MR-2015-0249DOI2018-12-11T17:23:05Z2018-12-112016-01-01T00:00:00ZCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)This study compares a wound dressing based on bacterial cellulose/collagen (BC/COL) hydrogel in rat dorsum with commercial collagenase ointment and untreated wound. The hydrogel was characterized by Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier transformed-Infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). According to the In vivo test and macroscopic evaluation, BC/COL hydrogel showed a better repair of wounds and promoted statistically significant differences of tissue repair between treatments on the 7th day after surgery. Better quality, quantity and orientation evaluation of collagen fibers (p=0.0001) were observed in the BC/COL hydrogel and collagenase ointment groups in relation to the control group. The BC/COL hydrogel promoted better wound healing than collagenase and the control group, therefore, it can be considered a potential wound dressing for skin regeneration.eng106-116reponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | Bacterial cellulose/collagen hydrogel for wound healing De Sousa Moraes, Paula Rodrigues Fontes Bacterial cellulose Collagen Hydrogel Tissue repair Wound dressing |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | Bacterial cellulose Collagen Hydrogel Tissue repair Wound dressing |
| title | Bacterial cellulose/collagen hydrogel for wound healing |
| title_full | Bacterial cellulose/collagen hydrogel for wound healing |
| title_fullStr | Bacterial cellulose/collagen hydrogel for wound healing |
| title_full_unstemmed | Bacterial cellulose/collagen hydrogel for wound healing |
| title_short | Bacterial cellulose/collagen hydrogel for wound healing |
| title_sort | Bacterial cellulose/collagen hydrogel for wound healing |
| topic | Bacterial cellulose Collagen Hydrogel Tissue repair Wound dressing |
| topic_facet | Bacterial cellulose Collagen Hydrogel Tissue repair Wound dressing |
| url | http://hdl.handle.net/11449/176915 |
| visible | 1 |
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