Publicação
Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization
| Resumo: | Abstract Electrospun nanofibers from gelatin (G), chitosan (CS), and chitosan-polyvinyl alcohol (CS-PVA) were developed by electrospinning process. Mechanical properties were determined by the tensile test, the elastic modulus values of the nanofibers were G (15.418-34.34 MPa) and CS-PVA (17.44-126.427 MPa). The morphological characterization by SEM revealed that the systems with 15% G and 6% CS-PVA showed morphological homogeneity. Structural characterization by FTIR indicated an interaction among some functional groups of the component. Thermal analysis by DSC and TGA showed degradation temperatures for G (330 °C), CS (210 °C to 370 °C), and PVA (310 °C to 420 °C). The contact angles values denoted the hydrophilic nature of the material. Finally, the antimicrobial assay proved that both 15% G and 7% PVA on the CS-PVA system presented the best antimicrobial effect. The results indicate that the electrospun nanofibers fabricated with G or CS-PVA can be used as wound healing dressings. |
|---|---|
| Autores principais: | Campa-Siqueiros,Paola |
| Outros Autores: | Madera-Santana,Tomás Jesús; Ayala-Zavala,Jesús Fernando; López-Cervantes,Jaime; Castillo-Ortega,María Mónica; Herrera-Franco,Pedro Jesús |
| Assunto: | chitosan electrospinning gelatin PVA wound dressing |
| Ano: | 2020 |
| País: | Brasil |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | IBICT |
| Idioma: | inglês |
| Origem: | Oasisbr |
| _version_ | 1871510267402125312 |
|---|---|
| author | Campa-Siqueiros,Paola |
| author2 | Madera-Santana,Tomás Jesús Ayala-Zavala,Jesús Fernando López-Cervantes,Jaime Castillo-Ortega,María Mónica Herrera-Franco,Pedro Jesús |
| author2_role | author author author author author |
| author_facet | Campa-Siqueiros,Paola Madera-Santana,Tomás Jesús Ayala-Zavala,Jesús Fernando López-Cervantes,Jaime Castillo-Ortega,María Mónica Herrera-Franco,Pedro Jesús |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"Campa-Siqueiros,Paola\"},{\"Person.name\":\"Madera-Santana,Tomás Jesús\"},{\"Person.name\":\"Ayala-Zavala,Jesús Fernando\"},{\"Person.name\":\"López-Cervantes,Jaime\"},{\"Person.name\":\"Castillo-Ortega,María Mónica\"},{\"Person.name\":\"Herrera-Franco,Pedro Jesús\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Campa-Siqueiros,Paola Madera-Santana,Tomás Jesús Ayala-Zavala,Jesús Fernando López-Cervantes,Jaime Castillo-Ortega,María Mónica Herrera-Franco,Pedro Jesús |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | chitosan electrospinning gelatin PVA wound dressing |
| datacite.titles.title.fl_str_mv | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| dc.creator.none.fl_str_mv | Campa-Siqueiros,Paola Madera-Santana,Tomás Jesús Ayala-Zavala,Jesús Fernando López-Cervantes,Jaime Castillo-Ortega,María Mónica Herrera-Franco,Pedro Jesús |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282020000100404 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Associação Brasileira de Polímeros |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Polímeros v.30 n.1 2020 reponame:Polímeros (São Carlos. Online) instname:Associação Brasileira de Polímeros (ABPol) instacron:ABPO |
| dc.subject.none.fl_str_mv | chitosan electrospinning gelatin PVA wound dressing |
| dc.title.fl_str_mv | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Abstract Electrospun nanofibers from gelatin (G), chitosan (CS), and chitosan-polyvinyl alcohol (CS-PVA) were developed by electrospinning process. Mechanical properties were determined by the tensile test, the elastic modulus values of the nanofibers were G (15.418-34.34 MPa) and CS-PVA (17.44-126.427 MPa). The morphological characterization by SEM revealed that the systems with 15% G and 6% CS-PVA showed morphological homogeneity. Structural characterization by FTIR indicated an interaction among some functional groups of the component. Thermal analysis by DSC and TGA showed degradation temperatures for G (330 °C), CS (210 °C to 370 °C), and PVA (310 °C to 420 °C). The contact angles values denoted the hydrophilic nature of the material. Finally, the antimicrobial assay proved that both 15% G and 7% PVA on the CS-PVA system presented the best antimicrobial effect. The results indicate that the electrospun nanofibers fabricated with G or CS-PVA can be used as wound healing dressings. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | oasisbr_b6ed166670ae762b4f0df16eb8d007c1 |
| identifier.url.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282020000100404 |
| inst_facet_str | urn:organizationAcronym:oasisbr{{{_:::_}}}IBICT |
| instacron_str | OASISBR |
| institution | IBICT |
| instname_str | IBICT |
| language | eng |
| network_acronym_str | oasisbr |
| network_name_str | Oasisbr |
| oai_identifier_str | oai:scielo:S0104-14282020000100404 |
| organization_str_mv | urn:organizationAcronym:oasisbr |
| person_str_mv | Campa-Siqueiros,Paola Madera-Santana,Tomás Jesús Ayala-Zavala,Jesús Fernando López-Cervantes,Jaime Castillo-Ortega,María Mónica Herrera-Franco,Pedro Jesús |
| publishDate | 2020 |
| publisher.none.fl_str_mv | Associação Brasileira de Polímeros |
| repo_facet_str | urn:repositoryAcronym:oasisbr{{{_:::_}}}Oasisbr |
| reponame_str | Oasisbr |
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| service_str_mv | urn:repositoryAcronym:oasisbr |
| spelling | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterizationCampa-Siqueiros,PaolaMadera-Santana,Tomás JesúsAyala-Zavala,Jesús FernandoLópez-Cervantes,JaimeCastillo-Ortega,María MónicaHerrera-Franco,Pedro JesúschitosanelectrospinninggelatinPVAwound dressingopen accesshttp://purl.org/coar/access_right/c_abf2http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282020000100404URLhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282020000100404URLHasVersion2020-01-01Abstract Electrospun nanofibers from gelatin (G), chitosan (CS), and chitosan-polyvinyl alcohol (CS-PVA) were developed by electrospinning process. Mechanical properties were determined by the tensile test, the elastic modulus values of the nanofibers were G (15.418-34.34 MPa) and CS-PVA (17.44-126.427 MPa). The morphological characterization by SEM revealed that the systems with 15% G and 6% CS-PVA showed morphological homogeneity. Structural characterization by FTIR indicated an interaction among some functional groups of the component. Thermal analysis by DSC and TGA showed degradation temperatures for G (330 °C), CS (210 °C to 370 °C), and PVA (310 °C to 420 °C). The contact angles values denoted the hydrophilic nature of the material. Finally, the antimicrobial assay proved that both 15% G and 7% PVA on the CS-PVA system presented the best antimicrobial effect. The results indicate that the electrospun nanofibers fabricated with G or CS-PVA can be used as wound healing dressings.engtext/htmlAssociação Brasileira de PolímerosPolímeros v.30 n.1 2020reponame:Polímeros (São Carlos. Online)instname:Associação Brasileira de Polímeros (ABPol)instacron:ABPOjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization Campa-Siqueiros,Paola chitosan electrospinning gelatin PVA wound dressing |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | chitosan electrospinning gelatin PVA wound dressing |
| title | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| title_full | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| title_fullStr | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| title_full_unstemmed | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| title_short | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| title_sort | Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization |
| topic | chitosan electrospinning gelatin PVA wound dressing |
| topic_facet | chitosan electrospinning gelatin PVA wound dressing |
| url | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282020000100404 |
| visible | 1 |
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