Publication
Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo
| Summary: | This work makes an assessment of the dominant lethality of Mikania glomerata in male Wistar rats. Adult male received 1 mL of M. glomerata hydroalcoholic extract at a dose level of 3.3 g/kg body weight for 52 days and were mated with untreated females for seven weeks (group 1) or one week prior to the beginning of treatment and on the week following the end of treatment (group 2). The parameters analyzed were: number of implanted embryos, resorptions and corpora lutea; mating, gestation, preimplantation loss, implantation and resorption indexes (group 1); number of offspring and weaning animals (group 2). The administration of M. glomerata did not show any impairment of fertility and no significant difference in the parameters analyzed, suggesting an absence of mutagenic effect on Wistar rats. |
|---|---|
| Main Authors: | Sá,Rita de Cássia da Silveira e |
| Other Authors: | Leite,Magda Narciso; Peters,Vera Maria; Guerra,Martha de Oliveira; Almeida,Reinaldo Nóbrega de |
| Subject: | Mikania glomerata mutagenicity Wistar rat |
| Year: | 2006 |
| Country: | Brazil |
| Document type: | article |
| Access type: | open access |
| Associated institution: | IBICT |
| Language: | English |
| Origin: | Oasisbr |
| _version_ | 1871506745317130240 |
|---|---|
| author | Sá,Rita de Cássia da Silveira e |
| author2 | Leite,Magda Narciso Peters,Vera Maria Guerra,Martha de Oliveira Almeida,Reinaldo Nóbrega de |
| author2_role | author author author author |
| author_facet | Sá,Rita de Cássia da Silveira e Leite,Magda Narciso Peters,Vera Maria Guerra,Martha de Oliveira Almeida,Reinaldo Nóbrega de |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"Sá,Rita de Cássia da Silveira e\"},{\"Person.name\":\"Leite,Magda Narciso\"},{\"Person.name\":\"Peters,Vera Maria\"},{\"Person.name\":\"Guerra,Martha de Oliveira\"},{\"Person.name\":\"Almeida,Reinaldo Nóbrega de\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Sá,Rita de Cássia da Silveira e Leite,Magda Narciso Peters,Vera Maria Guerra,Martha de Oliveira Almeida,Reinaldo Nóbrega de |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Mikania glomerata mutagenicity Wistar rat |
| datacite.titles.title.fl_str_mv | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| dc.creator.none.fl_str_mv | Sá,Rita de Cássia da Silveira e Leite,Magda Narciso Peters,Vera Maria Guerra,Martha de Oliveira Almeida,Reinaldo Nóbrega de |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500009 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Instituto de Tecnologia do Paraná - Tecpar |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Brazilian Archives of Biology and Technology v.49 n.4 2006 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
| dc.subject.none.fl_str_mv | Mikania glomerata mutagenicity Wistar rat |
| dc.title.fl_str_mv | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | This work makes an assessment of the dominant lethality of Mikania glomerata in male Wistar rats. Adult male received 1 mL of M. glomerata hydroalcoholic extract at a dose level of 3.3 g/kg body weight for 52 days and were mated with untreated females for seven weeks (group 1) or one week prior to the beginning of treatment and on the week following the end of treatment (group 2). The parameters analyzed were: number of implanted embryos, resorptions and corpora lutea; mating, gestation, preimplantation loss, implantation and resorption indexes (group 1); number of offspring and weaning animals (group 2). The administration of M. glomerata did not show any impairment of fertility and no significant difference in the parameters analyzed, suggesting an absence of mutagenic effect on Wistar rats. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | oasisbr_a404b7cf80d2776c8e505905abf1ccb7 |
| identifier.url.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500009 |
| inst_facet_str | urn:organizationAcronym:oasisbr{{{_:::_}}}IBICT |
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| institution | IBICT |
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| language | eng |
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| organization_str_mv | urn:organizationAcronym:oasisbr |
| person_str_mv | Sá,Rita de Cássia da Silveira e Leite,Magda Narciso Peters,Vera Maria Guerra,Martha de Oliveira Almeida,Reinaldo Nóbrega de |
| publishDate | 2006 |
| publisher.none.fl_str_mv | Instituto de Tecnologia do Paraná - Tecpar |
| repo_facet_str | urn:repositoryAcronym:oasisbr{{{_:::_}}}Oasisbr |
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| spelling | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivoSá,Rita de Cássia da Silveira eLeite,Magda NarcisoPeters,Vera MariaGuerra,Martha de OliveiraAlmeida,Reinaldo Nóbrega deMikania glomeratamutagenicityWistar ratopen accesshttp://purl.org/coar/access_right/c_abf2http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500009URLhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500009URLHasVersion2006-07-01This work makes an assessment of the dominant lethality of Mikania glomerata in male Wistar rats. Adult male received 1 mL of M. glomerata hydroalcoholic extract at a dose level of 3.3 g/kg body weight for 52 days and were mated with untreated females for seven weeks (group 1) or one week prior to the beginning of treatment and on the week following the end of treatment (group 2). The parameters analyzed were: number of implanted embryos, resorptions and corpora lutea; mating, gestation, preimplantation loss, implantation and resorption indexes (group 1); number of offspring and weaning animals (group 2). The administration of M. glomerata did not show any impairment of fertility and no significant difference in the parameters analyzed, suggesting an absence of mutagenic effect on Wistar rats.engtext/htmlInstituto de Tecnologia do Paraná - TecparBrazilian Archives of Biology and Technology v.49 n.4 2006reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPARjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo Sá,Rita de Cássia da Silveira e Mikania glomerata mutagenicity Wistar rat |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | Mikania glomerata mutagenicity Wistar rat |
| title | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| title_full | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| title_fullStr | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| title_full_unstemmed | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| title_short | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| title_sort | Absence of mutagenic effect of Mikania glomerata hydroalcoholic extract on adult wistar rats in vivo |
| topic | Mikania glomerata mutagenicity Wistar rat |
| topic_facet | Mikania glomerata mutagenicity Wistar rat |
| url | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500009 |
| visible | 1 |
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