Publicação
Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review
| Resumo: | Abstract Introduction: Pycnodysostosis is a rare autosomal recessive syndrome that provides the abnormal bone metabolism that increases the susceptibility of patients to develop osteomyelitis. Objective: This systematic review was conducted to analyze the risk factors associated with the development of complications in the jaws (fractures and osteomyelitis), as well as their clinicalpathological characteristics and therapeutic approaches in patients with pycnodysostosis. Methods: Searches were performed in the PubMed, Web of Science, Scopus, Lilacs, and Cochrane databases. Case reports or case series that met the eligibility criteria according to the PRISMA statement were included. The full texts of 31 articles were retrieved. Twenty of these articles published between 1969 and 2018 were selected, which described 26 cases of osteomyelitis in patients with pycnodysostosis. Results: The mean age of the patients was 37.84 years; the male-to-female was 1.36:1. The mandible was the most affected site (76.9%). Tooth extraction was the main risk factor for osteomyelitis (61.5%), followed by infection (26.8%) and mandibular fracture (23.0%). Antibiotic therapy alone or combined with some surgical procedure was the treatment used in most cases (80.7%). Conclusion: The findings of this review showed that patients with pycnodysostosis are more likely to develop osteomyelitis of the jaws after surgical procedures, especially tooth extraction which remains the main risk factor for its establishment. In addition, prophylactic antibiotictherapy in the pre- and postoperative periods may prevent the development of osteomyelitis in pycnodysostosis. |
|---|---|
| Autores principais: | França,Glória Maria de |
| Outros Autores: | Felix,Fernanda Aragão; Morais,Everton Freitas de; Medeiros,Maurília Raquel de Souto; Andrade,Ana Cláudia de Macedo; Galvão,Hébel Cavalcanti |
| Assunto: | Pycnodysostosis Cathepsin K Osteomyelitis Diagnosis Jaws |
| Ano: | 2021 |
| País: | Brasil |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | IBICT |
| Idioma: | inglês |
| Origem: | Oasisbr |
| _version_ | 1871511366738640896 |
|---|---|
| author | França,Glória Maria de |
| author2 | Felix,Fernanda Aragão Morais,Everton Freitas de Medeiros,Maurília Raquel de Souto Andrade,Ana Cláudia de Macedo Galvão,Hébel Cavalcanti |
| author2_role | author author author author author |
| author_facet | França,Glória Maria de Felix,Fernanda Aragão Morais,Everton Freitas de Medeiros,Maurília Raquel de Souto Andrade,Ana Cláudia de Macedo Galvão,Hébel Cavalcanti |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"França,Glória Maria de\"},{\"Person.name\":\"Felix,Fernanda Aragão\"},{\"Person.name\":\"Morais,Everton Freitas de\"},{\"Person.name\":\"Medeiros,Maurília Raquel de Souto\"},{\"Person.name\":\"Andrade,Ana Cláudia de Macedo\"},{\"Person.name\":\"Galvão,Hébel Cavalcanti\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | França,Glória Maria de Felix,Fernanda Aragão Morais,Everton Freitas de Medeiros,Maurília Raquel de Souto Andrade,Ana Cláudia de Macedo Galvão,Hébel Cavalcanti |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Pycnodysostosis Cathepsin K Osteomyelitis Diagnosis Jaws |
| datacite.titles.title.fl_str_mv | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| dc.creator.none.fl_str_mv | França,Glória Maria de Felix,Fernanda Aragão Morais,Everton Freitas de Medeiros,Maurília Raquel de Souto Andrade,Ana Cláudia de Macedo Galvão,Hébel Cavalcanti |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942021000500620 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Brazilian Journal of Otorhinolaryngology v.87 n.5 2021 reponame:Brazilian Journal of Otorhinolaryngology instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) instacron:ABORL-CCF |
| dc.subject.none.fl_str_mv | Pycnodysostosis Cathepsin K Osteomyelitis Diagnosis Jaws |
| dc.title.fl_str_mv | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Abstract Introduction: Pycnodysostosis is a rare autosomal recessive syndrome that provides the abnormal bone metabolism that increases the susceptibility of patients to develop osteomyelitis. Objective: This systematic review was conducted to analyze the risk factors associated with the development of complications in the jaws (fractures and osteomyelitis), as well as their clinicalpathological characteristics and therapeutic approaches in patients with pycnodysostosis. Methods: Searches were performed in the PubMed, Web of Science, Scopus, Lilacs, and Cochrane databases. Case reports or case series that met the eligibility criteria according to the PRISMA statement were included. The full texts of 31 articles were retrieved. Twenty of these articles published between 1969 and 2018 were selected, which described 26 cases of osteomyelitis in patients with pycnodysostosis. Results: The mean age of the patients was 37.84 years; the male-to-female was 1.36:1. The mandible was the most affected site (76.9%). Tooth extraction was the main risk factor for osteomyelitis (61.5%), followed by infection (26.8%) and mandibular fracture (23.0%). Antibiotic therapy alone or combined with some surgical procedure was the treatment used in most cases (80.7%). Conclusion: The findings of this review showed that patients with pycnodysostosis are more likely to develop osteomyelitis of the jaws after surgical procedures, especially tooth extraction which remains the main risk factor for its establishment. In addition, prophylactic antibiotictherapy in the pre- and postoperative periods may prevent the development of osteomyelitis in pycnodysostosis. |
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| language | eng |
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| person_str_mv | França,Glória Maria de Felix,Fernanda Aragão Morais,Everton Freitas de Medeiros,Maurília Raquel de Souto Andrade,Ana Cláudia de Macedo Galvão,Hébel Cavalcanti |
| publishDate | 2021 |
| publisher.none.fl_str_mv | Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
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| spelling | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic reviewFrança,Glória Maria deFelix,Fernanda AragãoMorais,Everton Freitas deMedeiros,Maurília Raquel de SoutoAndrade,Ana Cláudia de MacedoGalvão,Hébel CavalcantiPycnodysostosisCathepsin KOsteomyelitisDiagnosisJawsopen accesshttp://purl.org/coar/access_right/c_abf2http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942021000500620URLhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942021000500620URLHasVersion2021-10-01Abstract Introduction: Pycnodysostosis is a rare autosomal recessive syndrome that provides the abnormal bone metabolism that increases the susceptibility of patients to develop osteomyelitis. Objective: This systematic review was conducted to analyze the risk factors associated with the development of complications in the jaws (fractures and osteomyelitis), as well as their clinicalpathological characteristics and therapeutic approaches in patients with pycnodysostosis. Methods: Searches were performed in the PubMed, Web of Science, Scopus, Lilacs, and Cochrane databases. Case reports or case series that met the eligibility criteria according to the PRISMA statement were included. The full texts of 31 articles were retrieved. Twenty of these articles published between 1969 and 2018 were selected, which described 26 cases of osteomyelitis in patients with pycnodysostosis. Results: The mean age of the patients was 37.84 years; the male-to-female was 1.36:1. The mandible was the most affected site (76.9%). Tooth extraction was the main risk factor for osteomyelitis (61.5%), followed by infection (26.8%) and mandibular fracture (23.0%). Antibiotic therapy alone or combined with some surgical procedure was the treatment used in most cases (80.7%). Conclusion: The findings of this review showed that patients with pycnodysostosis are more likely to develop osteomyelitis of the jaws after surgical procedures, especially tooth extraction which remains the main risk factor for its establishment. In addition, prophylactic antibiotictherapy in the pre- and postoperative periods may prevent the development of osteomyelitis in pycnodysostosis.engtext/htmlAssociação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.Brazilian Journal of Otorhinolaryngology v.87 n.5 2021reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCFjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review França,Glória Maria de Pycnodysostosis Cathepsin K Osteomyelitis Diagnosis Jaws |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | Pycnodysostosis Cathepsin K Osteomyelitis Diagnosis Jaws |
| title | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| title_full | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| title_fullStr | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| title_full_unstemmed | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| title_short | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| title_sort | Osteomyelitis of the jaws in patients with pycnodysostosis: a systematic review |
| topic | Pycnodysostosis Cathepsin K Osteomyelitis Diagnosis Jaws |
| topic_facet | Pycnodysostosis Cathepsin K Osteomyelitis Diagnosis Jaws |
| url | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942021000500620 |
| visible | 1 |
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