Publication
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy
| Summary: | INTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome. |
|---|---|
| Main Authors: | Sainju,Rup Kamal |
| Other Authors: | Wolf,Bethany Jacobs; Bonilha,Leonardo; Martz,Gabriel |
| Subject: | epilepsy temporal lobe epilepsy surgery electroencephalography |
| Year: | 2012 |
| Country: | Brazil |
| Document type: | article |
| Access type: | open access |
| Associated institution: | IBICT |
| Language: | English |
| Origin: | Oasisbr |
| _version_ | 1871510505633349632 |
|---|---|
| author | Sainju,Rup Kamal |
| author2 | Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
| author2_role | author author author |
| author_facet | Sainju,Rup Kamal Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"Sainju,Rup Kamal\"},{\"Person.name\":\"Wolf,Bethany Jacobs\"},{\"Person.name\":\"Bonilha,Leonardo\"},{\"Person.name\":\"Martz,Gabriel\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Sainju,Rup Kamal Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | epilepsy temporal lobe epilepsy surgery electroencephalography |
| datacite.titles.title.fl_str_mv | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| dc.creator.none.fl_str_mv | Sainju,Rup Kamal Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Academia Brasileira de Neurologia - ABNEURO |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Arquivos de Neuro-Psiquiatria v.70 n.9 2012 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
| dc.subject.none.fl_str_mv | epilepsy temporal lobe epilepsy surgery electroencephalography |
| dc.title.fl_str_mv | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | INTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | oasisbr_9dcfb9b3b2ffdadbd5e2ada258b9cc80 |
| identifier.url.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009 |
| inst_facet_str | urn:organizationAcronym:oasisbr{{{_:::_}}}IBICT |
| instacron_str | OASISBR |
| institution | IBICT |
| instname_str | IBICT |
| language | eng |
| network_acronym_str | oasisbr |
| network_name_str | Oasisbr |
| oai_identifier_str | oai:scielo:S0004-282X2012000900009 |
| organization_str_mv | urn:organizationAcronym:oasisbr |
| person_str_mv | Sainju,Rup Kamal Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
| publishDate | 2012 |
| publisher.none.fl_str_mv | Academia Brasileira de Neurologia - ABNEURO |
| repo_facet_str | urn:repositoryAcronym:oasisbr{{{_:::_}}}Oasisbr |
| reponame_str | Oasisbr |
| repository_id_str | urn:repositoryAcronym:oasisbr |
| service_str_mv | urn:repositoryAcronym:oasisbr |
| spelling | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsySainju,Rup KamalWolf,Bethany JacobsBonilha,LeonardoMartz,Gabrielepilepsytemporal lobeepilepsy surgeryelectroencephalographyopen accesshttp://purl.org/coar/access_right/c_abf2http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009URLhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009URLHasVersion2012-09-01INTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome.engtext/htmlAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.70 n.9 2012reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEUROjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy Sainju,Rup Kamal epilepsy temporal lobe epilepsy surgery electroencephalography |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | epilepsy temporal lobe epilepsy surgery electroencephalography |
| title | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_full | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_fullStr | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_full_unstemmed | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_short | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| title_sort | Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
| topic | epilepsy temporal lobe epilepsy surgery electroencephalography |
| topic_facet | epilepsy temporal lobe epilepsy surgery electroencephalography |
| url | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009 |
| visible | 1 |
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