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Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study

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Resumo:OBJECTIVES: Remarkable changes in the epidemiology of abdominal aortic aneurysm (AAA) have occurred in many countries during last few decades, which have also affected Brazilian mortality concurrently. This study aimed to investigate mortality trends related to AAA mortality in Brazil from 2000 to 2016. METHODS: Annual AAA mortality data was extracted from the public databases of the Mortality Information System, and processed by the Multiple Cause Tabulator. RESULTS: In Brazil, 2000 through 2016, AAA occurred in 69,513 overall deaths; in 79.6% as underlying and in 20.4% as an associated cause of death, corresponding to rates respectively of 2.45, 1.95 and 0.50 deaths per 100,000 population; 65.4% male and 34.6% female; 60.6% in the Southeast region. The mean ages at death were 71.141 years overall, and 70.385 years and 72.573 years for men and women, respectively. Ruptured AAA occurred in 64.3% of the deaths where AAA was an underlying cause, and in 18.0% of the deaths where AAA was an associated cause. The standardized rates increased during 2000–2008, followed by a decrease during 2008–2016, resulting in an average annual percent change decline of -0.2 (confidence interval [CI], -0.5 to 0.2) for the entire 2000–2016 period. As associated causes, shock (39.2%), hemorrhages (33.0%), and hypertensive diseases (26.7%) prevailed with ruptured aneurysms, while hypertensive diseases (29.4%) were associated with unruptured aneurysms. A significant seasonal variation, highest during autumn and followed by in winter, was observed in the overall ruptured and unruptured AAA deaths. CONCLUSIONS: This study highlights the need to accurately document epidemiologic trends related to AAA in Brazil. We demonstrate the burden of AAA on mortality in older individuals, and our results may assist with effective planning of mortality prevention and control in patients with AAA.
Autores principais:Santo, Augusto Hasiak
Outros Autores:Puech-Leão, Pedro; Krutman, Mariana
Assunto:Abdominal Aortic Aneurysm Mortality Trends Cause of Death Seasonality
Ano:2021
País:Brasil
Tipo de documento:artigo
Tipo de acesso:unknown
Instituição associada:IBICT
Idioma:inglês
Origem:Oasisbr
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author Santo, Augusto Hasiak
author2 Puech-Leão, Pedro
Krutman, Mariana
author2_role author
author
author_facet Santo, Augusto Hasiak
Puech-Leão, Pedro
Krutman, Mariana
author_role author
country_str BR
creators_json_txt [{\"Person.name\":\"Santo, Augusto Hasiak\"},{\"Person.name\":\"Puech-Leão, Pedro\"},{\"Person.name\":\"Krutman, Mariana\"}]
datacite.creators.creator.creatorName.fl_str_mv Santo, Augusto Hasiak
Puech-Leão, Pedro
Krutman, Mariana
datacite.subjects.subject.fl_str_mv Abdominal Aortic Aneurysm
Mortality Trends
Cause of Death
Seasonality
datacite.titles.title.fl_str_mv Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
dc.creator.none.fl_str_mv Santo, Augusto Hasiak
Puech-Leão, Pedro
Krutman, Mariana
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://doi.org/10.6061/clinics/2021/e2388
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; v. 76 (2021); e2388
Clinics; Vol. 76 (2021); e2388
Clinics; Vol. 76 (2021); e2388
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
dc.subject.none.fl_str_mv Abdominal Aortic Aneurysm
Mortality Trends
Cause of Death
Seasonality
dc.title.fl_str_mv Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description OBJECTIVES: Remarkable changes in the epidemiology of abdominal aortic aneurysm (AAA) have occurred in many countries during last few decades, which have also affected Brazilian mortality concurrently. This study aimed to investigate mortality trends related to AAA mortality in Brazil from 2000 to 2016. METHODS: Annual AAA mortality data was extracted from the public databases of the Mortality Information System, and processed by the Multiple Cause Tabulator. RESULTS: In Brazil, 2000 through 2016, AAA occurred in 69,513 overall deaths; in 79.6% as underlying and in 20.4% as an associated cause of death, corresponding to rates respectively of 2.45, 1.95 and 0.50 deaths per 100,000 population; 65.4% male and 34.6% female; 60.6% in the Southeast region. The mean ages at death were 71.141 years overall, and 70.385 years and 72.573 years for men and women, respectively. Ruptured AAA occurred in 64.3% of the deaths where AAA was an underlying cause, and in 18.0% of the deaths where AAA was an associated cause. The standardized rates increased during 2000–2008, followed by a decrease during 2008–2016, resulting in an average annual percent change decline of -0.2 (confidence interval [CI], -0.5 to 0.2) for the entire 2000–2016 period. As associated causes, shock (39.2%), hemorrhages (33.0%), and hypertensive diseases (26.7%) prevailed with ruptured aneurysms, while hypertensive diseases (29.4%) were associated with unruptured aneurysms. A significant seasonal variation, highest during autumn and followed by in winter, was observed in the overall ruptured and unruptured AAA deaths. CONCLUSIONS: This study highlights the need to accurately document epidemiologic trends related to AAA in Brazil. We demonstrate the burden of AAA on mortality in older individuals, and our results may assist with effective planning of mortality prevention and control in patients with AAA.
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person_str_mv Santo, Augusto Hasiak
Puech-Leão, Pedro
Krutman, Mariana
publishDate 2021
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
repo_facet_str urn:repositoryAcronym:oasisbr{{{_:::_}}}Oasisbr
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spelling Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death studySanto, Augusto HasiakPuech-Leão, PedroKrutman, MarianaAbdominal Aortic AneurysmMortality TrendsCause of DeathSeasonalityCopyright (c) 2021 Clinicsopen accesshttp://purl.org/coar/access_right/c_abf2https://doi.org/10.6061/clinics/2021/e2388DOIhttps://www.revistas.usp.br/clinics/article/view/191758URLHasVersionhttps://www.revistas.usp.br/clinics/article/view/191758/176654URLHasVersionhttps://doi.org/10.6061/clinics/2021/e2388DOI2021-11-09OBJECTIVES: Remarkable changes in the epidemiology of abdominal aortic aneurysm (AAA) have occurred in many countries during last few decades, which have also affected Brazilian mortality concurrently. This study aimed to investigate mortality trends related to AAA mortality in Brazil from 2000 to 2016. METHODS: Annual AAA mortality data was extracted from the public databases of the Mortality Information System, and processed by the Multiple Cause Tabulator. RESULTS: In Brazil, 2000 through 2016, AAA occurred in 69,513 overall deaths; in 79.6% as underlying and in 20.4% as an associated cause of death, corresponding to rates respectively of 2.45, 1.95 and 0.50 deaths per 100,000 population; 65.4% male and 34.6% female; 60.6% in the Southeast region. The mean ages at death were 71.141 years overall, and 70.385 years and 72.573 years for men and women, respectively. Ruptured AAA occurred in 64.3% of the deaths where AAA was an underlying cause, and in 18.0% of the deaths where AAA was an associated cause. The standardized rates increased during 2000–2008, followed by a decrease during 2008–2016, resulting in an average annual percent change decline of -0.2 (confidence interval [CI], -0.5 to 0.2) for the entire 2000–2016 period. As associated causes, shock (39.2%), hemorrhages (33.0%), and hypertensive diseases (26.7%) prevailed with ruptured aneurysms, while hypertensive diseases (29.4%) were associated with unruptured aneurysms. A significant seasonal variation, highest during autumn and followed by in winter, was observed in the overall ruptured and unruptured AAA deaths. CONCLUSIONS: This study highlights the need to accurately document epidemiologic trends related to AAA in Brazil. We demonstrate the burden of AAA on mortality in older individuals, and our results may assist with effective planning of mortality prevention and control in patients with AAA.engapplication/pdfHospital das Clínicas, Faculdade de Medicina, Universidade de São PauloClinics; v. 76 (2021); e2388Clinics; Vol. 76 (2021); e2388Clinics; Vol. 76 (2021); e23881980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85
spellingShingle Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
Santo, Augusto Hasiak
Abdominal Aortic Aneurysm
Mortality Trends
Cause of Death
Seasonality
status SINGLETON
status_str VoR
subject.fl_str_mv Abdominal Aortic Aneurysm
Mortality Trends
Cause of Death
Seasonality
title Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
title_full Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
title_fullStr Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
title_full_unstemmed Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
title_short Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
title_sort Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study
topic Abdominal Aortic Aneurysm
Mortality Trends
Cause of Death
Seasonality
topic_facet Abdominal Aortic Aneurysm
Mortality Trends
Cause of Death
Seasonality
url https://doi.org/10.6061/clinics/2021/e2388
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