Publicação
Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
| Resumo: | In this study the role of different metal centers (magnesium, zinc and copper) on the enhancement of the hydrophilic character of metallochlorophylls, was evaluated. The solvatochromism as well as the aggregation process for these compounds in water/ethanol mixtures at different volume ratios were evaluated using Fluorescence, and Resonant Light Scattering (RLS) measurements, aiming to characterize the behavior of these compounds. Independently on the studied metallochlorophyll, the presence of at least 60% of water results in a considerable increase in the fluorescence emission, probably a direct consequence of a lower aggregation of these compounds, which is confirmed by the results from RLS measurements. Additionally, the results suggest that magnesium and zinc chlorophyll should be promising phototherapeutic agents for Photodynamic Therapy. |
|---|---|
| Autores principais: | Moreira,Leonardo M. |
| Outros Autores: | Lima,Adriana; Soares,Rafael R. S.; Batistela,Vagner R.; Gerola,Adriana P.; Hioka,Noboru; Bonacin,Juliano A.; Severino,Divinomar; Baptista,Mauricio S.; Machado,Antônio E. da Hora; Rodrigues,Máira R.; Codognoto,Lúcia; Oliveira,Hueder P. M. de |
| Assunto: | fluorescence spectroscopy resonant light scattering metallochlorophylls photodynamic therapy |
| Ano: | 2009 |
| País: | Brasil |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | IBICT |
| Idioma: | inglês |
| Origem: | Oasisbr |
| _version_ | 1871506588967108608 |
|---|---|
| author | Moreira,Leonardo M. |
| author2 | Lima,Adriana Soares,Rafael R. S. Batistela,Vagner R. Gerola,Adriana P. Hioka,Noboru Bonacin,Juliano A. Severino,Divinomar Baptista,Mauricio S. Machado,Antônio E. da Hora Rodrigues,Máira R. Codognoto,Lúcia Oliveira,Hueder P. M. de |
| author2_role | author author author author author author author author author author author author |
| author_facet | Moreira,Leonardo M. Lima,Adriana Soares,Rafael R. S. Batistela,Vagner R. Gerola,Adriana P. Hioka,Noboru Bonacin,Juliano A. Severino,Divinomar Baptista,Mauricio S. Machado,Antônio E. da Hora Rodrigues,Máira R. Codognoto,Lúcia Oliveira,Hueder P. M. de |
| author_role | author |
| country_str | BR |
| creators_json_txt | [{\"Person.name\":\"Moreira,Leonardo M.\"},{\"Person.name\":\"Lima,Adriana\"},{\"Person.name\":\"Soares,Rafael R. S.\"},{\"Person.name\":\"Batistela,Vagner R.\"},{\"Person.name\":\"Gerola,Adriana P.\"},{\"Person.name\":\"Hioka,Noboru\"},{\"Person.name\":\"Bonacin,Juliano A.\"},{\"Person.name\":\"Severino,Divinomar\"},{\"Person.name\":\"Baptista,Mauricio S.\"},{\"Person.name\":\"Machado,Antônio E. da Hora\"},{\"Person.name\":\"Rodrigues,Máira R.\"},{\"Person.name\":\"Codognoto,Lúcia\"},{\"Person.name\":\"Oliveira,Hueder P. M. de\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Moreira,Leonardo M. Lima,Adriana Soares,Rafael R. S. Batistela,Vagner R. Gerola,Adriana P. Hioka,Noboru Bonacin,Juliano A. Severino,Divinomar Baptista,Mauricio S. Machado,Antônio E. da Hora Rodrigues,Máira R. Codognoto,Lúcia Oliveira,Hueder P. M. de |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | fluorescence spectroscopy resonant light scattering metallochlorophylls photodynamic therapy |
| datacite.titles.title.fl_str_mv | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| dc.creator.none.fl_str_mv | Moreira,Leonardo M. Lima,Adriana Soares,Rafael R. S. Batistela,Vagner R. Gerola,Adriana P. Hioka,Noboru Bonacin,Juliano A. Severino,Divinomar Baptista,Mauricio S. Machado,Antônio E. da Hora Rodrigues,Máira R. Codognoto,Lúcia Oliveira,Hueder P. M. de |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Brasileira de Química |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Journal of the Brazilian Chemical Society v.20 n.9 2009 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
| dc.subject.none.fl_str_mv | fluorescence spectroscopy resonant light scattering metallochlorophylls photodynamic therapy |
| dc.title.fl_str_mv | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | In this study the role of different metal centers (magnesium, zinc and copper) on the enhancement of the hydrophilic character of metallochlorophylls, was evaluated. The solvatochromism as well as the aggregation process for these compounds in water/ethanol mixtures at different volume ratios were evaluated using Fluorescence, and Resonant Light Scattering (RLS) measurements, aiming to characterize the behavior of these compounds. Independently on the studied metallochlorophyll, the presence of at least 60% of water results in a considerable increase in the fluorescence emission, probably a direct consequence of a lower aggregation of these compounds, which is confirmed by the results from RLS measurements. Additionally, the results suggest that magnesium and zinc chlorophyll should be promising phototherapeutic agents for Photodynamic Therapy. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | oasisbr_756f86a835a9ca98f584b5040ab33cae |
| identifier.url.fl_str_mv | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013 |
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| institution | IBICT |
| instname_str | IBICT |
| language | eng |
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| oai_identifier_str | oai:scielo:S0103-50532009000900013 |
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| person_str_mv | Moreira,Leonardo M. Lima,Adriana Soares,Rafael R. S. Batistela,Vagner R. Gerola,Adriana P. Hioka,Noboru Bonacin,Juliano A. Severino,Divinomar Baptista,Mauricio S. Machado,Antônio E. da Hora Rodrigues,Máira R. Codognoto,Lúcia Oliveira,Hueder P. M. de |
| publishDate | 2009 |
| publisher.none.fl_str_mv | Sociedade Brasileira de Química |
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| spelling | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation propertiesMoreira,Leonardo M.Lima,AdrianaSoares,Rafael R. S.Batistela,Vagner R.Gerola,Adriana P.Hioka,NoboruBonacin,Juliano A.Severino,DivinomarBaptista,Mauricio S.Machado,Antônio E. da HoraRodrigues,Máira R.Codognoto,LúciaOliveira,Hueder P. M. defluorescence spectroscopyresonant light scatteringmetallochlorophyllsphotodynamic therapyopen accesshttp://purl.org/coar/access_right/c_abf2http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013URLhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013URLHasVersion2009-01-01In this study the role of different metal centers (magnesium, zinc and copper) on the enhancement of the hydrophilic character of metallochlorophylls, was evaluated. The solvatochromism as well as the aggregation process for these compounds in water/ethanol mixtures at different volume ratios were evaluated using Fluorescence, and Resonant Light Scattering (RLS) measurements, aiming to characterize the behavior of these compounds. Independently on the studied metallochlorophyll, the presence of at least 60% of water results in a considerable increase in the fluorescence emission, probably a direct consequence of a lower aggregation of these compounds, which is confirmed by the results from RLS measurements. Additionally, the results suggest that magnesium and zinc chlorophyll should be promising phototherapeutic agents for Photodynamic Therapy.engtext/htmlSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.20 n.9 2009reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties Moreira,Leonardo M. fluorescence spectroscopy resonant light scattering metallochlorophylls photodynamic therapy |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | fluorescence spectroscopy resonant light scattering metallochlorophylls photodynamic therapy |
| title | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| title_full | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| title_fullStr | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| title_full_unstemmed | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| title_short | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| title_sort | Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties |
| topic | fluorescence spectroscopy resonant light scattering metallochlorophylls photodynamic therapy |
| topic_facet | fluorescence spectroscopy resonant light scattering metallochlorophylls photodynamic therapy |
| url | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013 |
| visible | 1 |
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