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Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)

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Summary:Titanium is used in orthopedic and orthodontic implants because it has good corrosion resistance and excellent biocompatibility. Thus, studies seek to obtain a coating to improve the adhesion between the bone and the implant, by modifying the metal’s surface. The objective of this work was to biomimetically coat C.P. Ti with hydroxyapatite doped with silver nitrate, a component with antimicrobial properties, coating the metallic-ceramic composite with a polycaprolactone polymer film, which is known by generate improved implant-tissue interaction, and reducing postoperative complications from bacterial infections. The characterization of the material demonstrated the existence of the coating overall surface of the metallic substrate. The results obtained from the bacterial culture tests with Staphylococcus aureus showed that nitrate was effective in reducing the amount of live bacteria present in the supernatant, as well as those adhered to the surface of the material. In addition, the polymeric coating did not prevent the release of the bactericidal agent, not interfering in the effect there.
Main Authors:Ferreira,Carolina Cruz
Other Authors:Sousa,Lucíola Lucena de; Ricci,Virgilio Pereira; Rigo,Eliana Cristina da Silva; Ramos,Alfeu Saraiva; Campos,Maria Gabriela Nogueira; Mariano,Neide Aparecida
Subject:Titanium hydroxyapatite polycaprolactone biomimetic coating
Year:2019
Country:Brazil
Document type:article
Access type:open access
Associated institution:IBICT
Language:English
Origin:Oasisbr
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author Ferreira,Carolina Cruz
author2 Sousa,Lucíola Lucena de
Ricci,Virgilio Pereira
Rigo,Eliana Cristina da Silva
Ramos,Alfeu Saraiva
Campos,Maria Gabriela Nogueira
Mariano,Neide Aparecida
author2_role author
author
author
author
author
author
author_facet Ferreira,Carolina Cruz
Sousa,Lucíola Lucena de
Ricci,Virgilio Pereira
Rigo,Eliana Cristina da Silva
Ramos,Alfeu Saraiva
Campos,Maria Gabriela Nogueira
Mariano,Neide Aparecida
author_role author
country_str BR
creators_json_txt [{\"Person.name\":\"Ferreira,Carolina Cruz\"},{\"Person.name\":\"Sousa,Lucíola Lucena de\"},{\"Person.name\":\"Ricci,Virgilio Pereira\"},{\"Person.name\":\"Rigo,Eliana Cristina da Silva\"},{\"Person.name\":\"Ramos,Alfeu Saraiva\"},{\"Person.name\":\"Campos,Maria Gabriela Nogueira\"},{\"Person.name\":\"Mariano,Neide Aparecida\"}]
datacite.creators.creator.creatorName.fl_str_mv Ferreira,Carolina Cruz
Sousa,Lucíola Lucena de
Ricci,Virgilio Pereira
Rigo,Eliana Cristina da Silva
Ramos,Alfeu Saraiva
Campos,Maria Gabriela Nogueira
Mariano,Neide Aparecida
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Titanium
hydroxyapatite
polycaprolactone
biomimetic coating
datacite.titles.title.fl_str_mv Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
dc.creator.none.fl_str_mv Ferreira,Carolina Cruz
Sousa,Lucíola Lucena de
Ricci,Virgilio Pereira
Rigo,Eliana Cristina da Silva
Ramos,Alfeu Saraiva
Campos,Maria Gabriela Nogueira
Mariano,Neide Aparecida
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000700274
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Materials Research v.22 suppl.1 2019
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
dc.subject.none.fl_str_mv Titanium
hydroxyapatite
polycaprolactone
biomimetic coating
dc.title.fl_str_mv Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Titanium is used in orthopedic and orthodontic implants because it has good corrosion resistance and excellent biocompatibility. Thus, studies seek to obtain a coating to improve the adhesion between the bone and the implant, by modifying the metal’s surface. The objective of this work was to biomimetically coat C.P. Ti with hydroxyapatite doped with silver nitrate, a component with antimicrobial properties, coating the metallic-ceramic composite with a polycaprolactone polymer film, which is known by generate improved implant-tissue interaction, and reducing postoperative complications from bacterial infections. The characterization of the material demonstrated the existence of the coating overall surface of the metallic substrate. The results obtained from the bacterial culture tests with Staphylococcus aureus showed that nitrate was effective in reducing the amount of live bacteria present in the supernatant, as well as those adhered to the surface of the material. In addition, the polymeric coating did not prevent the release of the bactericidal agent, not interfering in the effect there.
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organization_str_mv urn:organizationAcronym:oasisbr
person_str_mv Ferreira,Carolina Cruz
Sousa,Lucíola Lucena de
Ricci,Virgilio Pereira
Rigo,Eliana Cristina da Silva
Ramos,Alfeu Saraiva
Campos,Maria Gabriela Nogueira
Mariano,Neide Aparecida
publishDate 2019
publisher.none.fl_str_mv ABM, ABC, ABPol
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spelling Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)Ferreira,Carolina CruzSousa,Lucíola Lucena deRicci,Virgilio PereiraRigo,Eliana Cristina da SilvaRamos,Alfeu SaraivaCampos,Maria Gabriela NogueiraMariano,Neide AparecidaTitaniumhydroxyapatitepolycaprolactonebiomimetic coatingopen accesshttp://purl.org/coar/access_right/c_abf2http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000700274URLhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000700274URLHasVersion2019-01-01Titanium is used in orthopedic and orthodontic implants because it has good corrosion resistance and excellent biocompatibility. Thus, studies seek to obtain a coating to improve the adhesion between the bone and the implant, by modifying the metal’s surface. The objective of this work was to biomimetically coat C.P. Ti with hydroxyapatite doped with silver nitrate, a component with antimicrobial properties, coating the metallic-ceramic composite with a polycaprolactone polymer film, which is known by generate improved implant-tissue interaction, and reducing postoperative complications from bacterial infections. The characterization of the material demonstrated the existence of the coating overall surface of the metallic substrate. The results obtained from the bacterial culture tests with Staphylococcus aureus showed that nitrate was effective in reducing the amount of live bacteria present in the supernatant, as well as those adhered to the surface of the material. In addition, the polymeric coating did not prevent the release of the bactericidal agent, not interfering in the effect there.engtext/htmlABM, ABC, ABPolMaterials Research v.22 suppl.1 2019reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOLjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85
spellingShingle Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
Ferreira,Carolina Cruz
Titanium
hydroxyapatite
polycaprolactone
biomimetic coating
status SINGLETON
status_str VoR
subject.fl_str_mv Titanium
hydroxyapatite
polycaprolactone
biomimetic coating
title Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
title_full Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
title_fullStr Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
title_full_unstemmed Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
title_short Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
title_sort Titanium Biomimetically Coated With Hydroxyapatite, Silver Nitrate and Polycaprolactone, for Use In Biomaterials (Biomedicine)
topic Titanium
hydroxyapatite
polycaprolactone
biomimetic coating
topic_facet Titanium
hydroxyapatite
polycaprolactone
biomimetic coating
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392019000700274
visible 1

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