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Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications

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Resumo:Polydimethylsiloxane (PDMS), due to its remarkable properties, is a suitable polymer for the production of microparticles with industrial and medical applications. The micro-sized PDMS liquid droplets suffer a pronounced shrinkage while curing to turn into solid particles. In this article, we report the calibration of the shrinkage phenomenon in the production of PDMS microparticles. Our results show that this shrinkage does not depend on the amount of curing agent in the PDMS precursor or on the addition of micro/nanoparticles to the mixture, but on the surface effects due to the relatively large droplet surface-to-volume ratio. Moreover, we have also investigated the addition of colour to the particles to improve their visualization/detection. The addition of colour by using pigments enhances the visualization of the contours of the PDMS microparticles, and reveals the capability of this technique to microencapsulate micro/nanoparticles in PDMS spheres with diameters below 10 μm. We demonstrate that the technique used in this work is able to work with a wide range of viscosities obtaining an acceptable degree of monodispersity.
Autores principais:Anes, Cláudia Filipa
Outros Autores:Pinho, Diana; Muñoz-Sánchez, Beatriz N.; Vega, E.J.; Lima, Rui A.
Assunto:Coloured PDMS Flow focusing Micro-sized PDMS particles Polydimethylsiloxane (PDMS) Shrinkage
Ano:2018
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade Politécnica de Bragança
Idioma:inglês
Origem:Biblioteca Digital da UPB
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author Anes, Cláudia Filipa
author2 Pinho, Diana
Muñoz-Sánchez, Beatriz N.
Vega, E.J.
Lima, Rui A.
author2_role author
author
author
author
author_facet Anes, Cláudia Filipa
Pinho, Diana
Muñoz-Sánchez, Beatriz N.
Vega, E.J.
Lima, Rui A.
author_role author
contributor_name_str_mv Biblioteca Digital da UPB
country_str PT
creators_json_txt [{\"Person.name\":\"Anes, Cláudia Filipa\"},{\"Person.name\":\"Pinho, Diana\",\"Person.identifier.cienciaID\":\"5214-ED0C-35E8\",\"Person.identifier.orcid\":\"0000-0002-3884-6496\"},{\"Person.name\":\"Muñoz-Sánchez, Beatriz N.\"},{\"Person.name\":\"Vega, E.J.\"},{\"Person.name\":\"Lima, Rui A.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital da UPB
datacite.creators.creator.creatorName.fl_str_mv Anes, Cláudia Filipa
Pinho, Diana
Muñoz-Sánchez, Beatriz N.
Vega, E.J.
Lima, Rui A.
datacite.date.Accepted.fl_str_mv 2018-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2018-01-19T10:00:00Z
datacite.date.embargoed.fl_str_mv 2018-01-19T10:00:00Z
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datacite.subjects.subject.fl_str_mv Coloured PDMS
Flow focusing
Micro-sized PDMS particles
Polydimethylsiloxane (PDMS)
Shrinkage
datacite.titles.title.fl_str_mv Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
dc.contributor.none.fl_str_mv Biblioteca Digital da UPB
dc.creator.none.fl_str_mv Anes, Cláudia Filipa
Pinho, Diana
Muñoz-Sánchez, Beatriz N.
Vega, E.J.
Lima, Rui A.
dc.date.Accepted.fl_str_mv 2018-01-01T00:00:00Z
dc.date.available.fl_str_mv 2018-01-19T10:00:00Z
dc.date.embargoed.fl_str_mv 2018-01-19T10:00:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/17909
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Coloured PDMS
Flow focusing
Micro-sized PDMS particles
Polydimethylsiloxane (PDMS)
Shrinkage
dc.title.fl_str_mv Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Polydimethylsiloxane (PDMS), due to its remarkable properties, is a suitable polymer for the production of microparticles with industrial and medical applications. The micro-sized PDMS liquid droplets suffer a pronounced shrinkage while curing to turn into solid particles. In this article, we report the calibration of the shrinkage phenomenon in the production of PDMS microparticles. Our results show that this shrinkage does not depend on the amount of curing agent in the PDMS precursor or on the addition of micro/nanoparticles to the mixture, but on the surface effects due to the relatively large droplet surface-to-volume ratio. Moreover, we have also investigated the addition of colour to the particles to improve their visualization/detection. The addition of colour by using pigments enhances the visualization of the contours of the PDMS microparticles, and reveals the capability of this technique to microencapsulate micro/nanoparticles in PDMS spheres with diameters below 10 μm. We demonstrate that the technique used in this work is able to work with a wide range of viscosities obtaining an acceptable degree of monodispersity.
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Muñoz-Sánchez, Beatriz N.
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spelling engen_ENPolydimethylsiloxane (PDMS), due to its remarkable properties, is a suitable polymer for the production of microparticles with industrial and medical applications. The micro-sized PDMS liquid droplets suffer a pronounced shrinkage while curing to turn into solid particles. In this article, we report the calibration of the shrinkage phenomenon in the production of PDMS microparticles. Our results show that this shrinkage does not depend on the amount of curing agent in the PDMS precursor or on the addition of micro/nanoparticles to the mixture, but on the surface effects due to the relatively large droplet surface-to-volume ratio. Moreover, we have also investigated the addition of colour to the particles to improve their visualization/detection. The addition of colour by using pigments enhances the visualization of the contours of the PDMS microparticles, and reveals the capability of this technique to microencapsulate micro/nanoparticles in PDMS spheres with diameters below 10 μm. We demonstrate that the technique used in this work is able to work with a wide range of viscosities obtaining an acceptable degree of monodispersity.application/pdfen_ENShrinkage and colour in the production of micro-sized PDMS particles for microfluidic applicationsAnes, Cláudia FilipaPersonalPinho, DianaDSpacehttp://dspace.org/items/02bf2dd9-33ed-4d87-b61d-ca39c51f8451DSpacehttp://dspace.org/items/02bf2dd9-33ed-4d87-b61d-ca39c51f8451PinhoDianaCiência IDhttps://www.ciencia-id.pt5214-ED0C-35E8ORCIDhttp://orcid.org0000-0002-3884-6496Muñoz-Sánchez, Beatriz N.Vega, E.J.Lima, Rui A.HostingInstitutionOrganizationalBiblioteca Digital da UPBe-mailmailto:dspace@unipb.ptdspace@unipb.ptISSNIsPartOf0960-1317DOIIsPartOf10.1088/1361-6439/aab7b92018-01-19T10:00:00Z20182018-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/17909http://purl.org/coar/access_right/c_abf2open accessColoured PDMSFlow focusingMicro-sized PDMS particlesPolydimethylsiloxane (PDMS)Shrinkage1915686 bytesFundação para a Ciência e a TecnologiaBlood Rheology and Red Blood Cell Migration in Microchannel Flowsinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F89077%2F2012/PTSFRH/BD/89077/2012SFRHCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaCentro de Estudos de Fenómenos de Transporteinfo:eu-repo/grantAgreement/FCT/5876/UID%2FEMS%2F00532%2F2013/PTUID/EMS/00532/20135876Crossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaCentro de Engenharia Mecânica e Sustentabilidade de RecursosCentro de Engenharia Mecânica e Sustentabilidade de Recursosinfo:eu-repo/grantAgreement/FCT/5876/UID%2FEMS%2F04077%2F2013/PTUID/EMS/04077/20135876Crossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaCentro de Engenharia Mecânica e Sustentabilidade de RecursosCentro de Engenharia Mecânica e Sustentabilidade de Recursosinfo:eu-repo/grantAgreement/FCT/5876/UID%2FEMS%2F04077%2F2013/PTUID/EMS/04077/20135876Crossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaNovos fluidos biomiméticos para aplicações biomédicasinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FQEQ-FTT%2F4287%2F2014/PTPTDC/QEQ-FTT/4287/20149471 - RIDTICrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaDevelopment of innovative biomimetic fluids for microfluidic applicationsinfo:eu-repo/grantAgreement/FCT//SFRH%2FBSAB%2F135419%2F2017/PTSFRH/BSAB/135419/2017Crossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.unipb.pt/bitstreams/3bbeb21f-9294-42e6-90b9-ddf08ac6dc64/download
spellingShingle Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
Anes, Cláudia Filipa
Coloured PDMS
Flow focusing
Micro-sized PDMS particles
Polydimethylsiloxane (PDMS)
Shrinkage
status SINGLETON
subject.fl_str_mv Coloured PDMS
Flow focusing
Micro-sized PDMS particles
Polydimethylsiloxane (PDMS)
Shrinkage
title Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
title_full Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
title_fullStr Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
title_full_unstemmed Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
title_short Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
title_sort Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications
topic Coloured PDMS
Flow focusing
Micro-sized PDMS particles
Polydimethylsiloxane (PDMS)
Shrinkage
topic_facet Coloured PDMS
Flow focusing
Micro-sized PDMS particles
Polydimethylsiloxane (PDMS)
Shrinkage
url http://hdl.handle.net/10198/17909
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