Publicação
Flow of red blood cells through microchannel with a confluence
| Resumo: | Micro-visualization techniques have been used to investigate the in vitro blood flow through straight glass capillaries. Although the glass microchannels present certain similarities to in vivo microcirculation, it is also clear that these kind of in vitro experiments differ from microvessels in several respects, such as: elasticity of microvessels, effect of the endothelial surface layer and microvascular networks composed with short irregular vessel segments which are linked by numerous bifurcations and convergences. Thus it was not surprising that several studies on blood flow in glass microtubes and in microvessels have yielded conflicting results with respect to blood viscosity and flow resistance. The main purpose of this work is to improve our understanding about the effect of a confluence on the rheological properties of in vitro blood. The flow behaviour of both pure water (PW) and dextran 40 (Dx40) containing about 14% (14Hct) of human red blood cells (RBCs) will be investigated by means of a confocal micro-PTV system. The experimental measurements obtained will be compared numerically by using the commercial finite element software package POLYFLOW® and different constitutive models to describe the rheology of the blood, namely: constant viscosity, power-law model and Carreau model. |
|---|---|
| Autores principais: | Leble, Vladimir |
| Outros Autores: | Lima, Rui A.; Fernandes, Carla S.; Dias, Ricardo P. |
| Assunto: | Red blood cells Velocity profiles Confluence Microchannel Confocal micro-PTV |
| Ano: | 2011 |
| País: | Portugal |
| Tipo de documento: | documento de conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Politécnica de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital da UPB |
| _version_ | 1877782859751620608 |
|---|---|
| author | Leble, Vladimir |
| author2 | Lima, Rui A. Fernandes, Carla S. Dias, Ricardo P. |
| author2_role | author author author |
| author_facet | Leble, Vladimir Lima, Rui A. Fernandes, Carla S. Dias, Ricardo P. |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital da UPB |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Leble, Vladimir\"},{\"Person.name\":\"Lima, Rui A.\",\"Person.identifier.cienciaID\":\"EE12-C3FB-349D\",\"Person.identifier.orcid\":\"0000-0003-3428-637X\",\"Person.identifier.researcherID\":\"H-5157-2016\",\"Person.identifier.scopusAuthorID\":\"18437397800\"},{\"Person.name\":\"Fernandes, Carla S.\",\"Person.identifier.cienciaID\":\"F319-3D67-9DB7\",\"Person.identifier.orcid\":\"0000-0002-3138-7493\",\"Person.identifier.researcherID\":\"A-4269-2015\",\"Person.identifier.scopusAuthorID\":\"8253740700\"},{\"Person.name\":\"Dias, Ricardo P.\",\"Person.identifier.orcid\":\"0000-0003-1503-998X\",\"Person.identifier.scopusAuthorID\":\"7102885151\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital da UPB |
| datacite.creators.creator.creatorName.fl_str_mv | Leble, Vladimir Lima, Rui A. Fernandes, Carla S. Dias, Ricardo P. |
| datacite.date.Accepted.fl_str_mv | 2011-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2014-08-01T15:17:23Z |
| datacite.date.embargoed.fl_str_mv | 2014-08-01T15:17:23Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Red blood cells Velocity profiles Confluence Microchannel Confocal micro-PTV |
| datacite.titles.title.fl_str_mv | Flow of red blood cells through microchannel with a confluence |
| dc.contributor.none.fl_str_mv | Biblioteca Digital da UPB |
| dc.creator.none.fl_str_mv | Leble, Vladimir Lima, Rui A. Fernandes, Carla S. Dias, Ricardo P. |
| dc.date.Accepted.fl_str_mv | 2011-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2014-08-01T15:17:23Z |
| dc.date.embargoed.fl_str_mv | 2014-08-01T15:17:23Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/10015 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Red blood cells Velocity profiles Confluence Microchannel Confocal micro-PTV |
| dc.title.fl_str_mv | Flow of red blood cells through microchannel with a confluence |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_c94f |
| description | Micro-visualization techniques have been used to investigate the in vitro blood flow through straight glass capillaries. Although the glass microchannels present certain similarities to in vivo microcirculation, it is also clear that these kind of in vitro experiments differ from microvessels in several respects, such as: elasticity of microvessels, effect of the endothelial surface layer and microvascular networks composed with short irregular vessel segments which are linked by numerous bifurcations and convergences. Thus it was not surprising that several studies on blood flow in glass microtubes and in microvessels have yielded conflicting results with respect to blood viscosity and flow resistance. The main purpose of this work is to improve our understanding about the effect of a confluence on the rheological properties of in vitro blood. The flow behaviour of both pure water (PW) and dextran 40 (Dx40) containing about 14% (14Hct) of human red blood cells (RBCs) will be investigated by means of a confocal micro-PTV system. The experimental measurements obtained will be compared numerically by using the commercial finite element software package POLYFLOW® and different constitutive models to describe the rheology of the blood, namely: constant viscosity, power-law model and Carreau model. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | conferenceObject |
| fulltext.url.fl_str_mv | https://bibliotecadigital.unipb.pt/bitstreams/00eedf18-e83b-4823-84e6-6d6db85e8077/download |
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| identifier.url.fl_str_mv | http://hdl.handle.net/10198/10015 |
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| person_str_mv | Leble, Vladimir Lima, Rui A. Lima, Rui A. https://www.ciencia-id.pt/EE12-C3FB-349D EE12-C3FB-349D http://orcid.org/0000-0003-3428-637X 0000-0003-3428-637X Fernandes, Carla S. Fernandes, Carla S. https://www.ciencia-id.pt/F319-3D67-9DB7 F319-3D67-9DB7 http://orcid.org/0000-0002-3138-7493 0000-0002-3138-7493 Dias, Ricardo P. Dias, Ricardo P. http://orcid.org/0000-0003-1503-998X 0000-0003-1503-998X |
| publishDate | 2011 |
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| spelling | engporMicro-visualization techniques have been used to investigate the in vitro blood flow through straight glass capillaries. Although the glass microchannels present certain similarities to in vivo microcirculation, it is also clear that these kind of in vitro experiments differ from microvessels in several respects, such as: elasticity of microvessels, effect of the endothelial surface layer and microvascular networks composed with short irregular vessel segments which are linked by numerous bifurcations and convergences. Thus it was not surprising that several studies on blood flow in glass microtubes and in microvessels have yielded conflicting results with respect to blood viscosity and flow resistance. The main purpose of this work is to improve our understanding about the effect of a confluence on the rheological properties of in vitro blood. The flow behaviour of both pure water (PW) and dextran 40 (Dx40) containing about 14% (14Hct) of human red blood cells (RBCs) will be investigated by means of a confocal micro-PTV system. The experimental measurements obtained will be compared numerically by using the commercial finite element software package POLYFLOW® and different constitutive models to describe the rheology of the blood, namely: constant viscosity, power-law model and Carreau model.application/pdfporFlow of red blood cells through microchannel with a confluenceLeble, VladimirPersonalLima, Rui A.DSpacehttp://dspace.org/items/7b50c499-8095-4f4f-8b1b-fa7388e4ff62DSpacehttp://dspace.org/items/7b50c499-8095-4f4f-8b1b-fa7388e4ff62LimaRui A.Ciência IDhttps://www.ciencia-id.ptEE12-C3FB-349DORCIDhttp://orcid.org0000-0003-3428-637XResearcher IDhttps://www.researcherid.comH-5157-2016Scopus Author IDhttps://www.scopus.com18437397800PersonalFernandes, Carla S.DSpacehttp://dspace.org/items/8f9cf139-cfef-4025-ba87-56425618bc6eDSpacehttp://dspace.org/items/8f9cf139-cfef-4025-ba87-56425618bc6eFernandesCarla S.Ciência IDhttps://www.ciencia-id.ptF319-3D67-9DB7ORCIDhttp://orcid.org0000-0002-3138-7493Researcher IDhttps://www.researcherid.comA-4269-2015Scopus Author IDhttps://www.scopus.com8253740700PersonalDias, Ricardo P.DSpacehttp://dspace.org/items/5e7df3f1-9852-4d4b-8d5a-4e69eb79b164DSpacehttp://dspace.org/items/5e7df3f1-9852-4d4b-8d5a-4e69eb79b164DiasRicardo P.ORCIDhttp://orcid.org0000-0003-1503-998XScopus Author IDhttps://www.scopus.com7102885151HostingInstitutionOrganizationalBiblioteca Digital da UPBe-mailmailto:dspace@unipb.ptdspace@unipb.pt2014-08-01T15:17:23Z20112011-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/10015http://purl.org/coar/access_right/c_abf2open accessRed blood cellsVelocity profilesConfluenceMicrochannelConfocal micro-PTV569053 bytesother research producthttp://purl.org/coar/resource_type/c_c94fconference objecthttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.unipb.pt/bitstreams/00eedf18-e83b-4823-84e6-6d6db85e8077/downloadCongress on Numerical Methods in Engineering 2011190190Coimbra |
| spellingShingle | Flow of red blood cells through microchannel with a confluence Leble, Vladimir Red blood cells Velocity profiles Confluence Microchannel Confocal micro-PTV |
| status | SINGLETON |
| subject.fl_str_mv | Red blood cells Velocity profiles Confluence Microchannel Confocal micro-PTV |
| title | Flow of red blood cells through microchannel with a confluence |
| title_full | Flow of red blood cells through microchannel with a confluence |
| title_fullStr | Flow of red blood cells through microchannel with a confluence |
| title_full_unstemmed | Flow of red blood cells through microchannel with a confluence |
| title_short | Flow of red blood cells through microchannel with a confluence |
| title_sort | Flow of red blood cells through microchannel with a confluence |
| topic | Red blood cells Velocity profiles Confluence Microchannel Confocal micro-PTV |
| topic_facet | Red blood cells Velocity profiles Confluence Microchannel Confocal micro-PTV |
| url | http://hdl.handle.net/10198/10015 |
| visible | 1 |
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