Publicação
Electrochemistry of Flavonoids: A Comprehensive Review
| Resumo: | Flavonoids represent a large group of aromatic amino acids that are extensively disseminated in plants. More than six thousand different flavonoids have been isolated and identified. They are important components of the human diet, presenting a broad spectrum of health benefits, including antibacterial, antiviral, antimicrobial, antineoplastic, anti-mutagenic, anti-inflammatory, anti-allergic, immunomodulatory, vasodilatory and cardioprotective properties. They are now considered indispensable compounds in the healthcare, food, pharmaceutical, cosmetic and biotechnology industries. All flavonoids are electroactive, and a relationship between their electron-transfer properties and radical-scavenging activity has been highlighted. This review seeks to provide a comprehensive overview concerning the electron-transfer reactions in flavonoids, from the point of view of their in-vitro antioxidant mode of action. Flavonoid redox behavior is related to the oxidation of the phenolic hydroxy groups present in their structures. The fundamental principles concerning the redox behavior of flavonoids will be described, and the phenol moiety oxidation pathways and the effect of substituents and experimental conditions on flavonoid electrochemical behavior will be discussed. The final sections will focus on the electroanalysis of flavonoids in natural products and their identification in highly complex matrixes, such as fruits, vegetables, beverages, food supplements, pharmaceutical compounds and human body fluids, relevant for food quality control, nutrition, and healthcare research. |
|---|---|
| Autores principais: | Chiorcea-Paquim, Ana Maria |
| Assunto: | flavonoids polyphenols phenolic compounds electrochemistry electrochemical sensing antioxidant |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Coimbra |
| Idioma: | inglês |
| Origem: | Estudo Geral - Universidade de Coimbra |
| _version_ | 1877781013983133696 |
|---|---|
| author | Chiorcea-Paquim, Ana Maria |
| author_facet | Chiorcea-Paquim, Ana Maria |
| author_role | author |
| contributor_name_str_mv | Estudo Geral |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Chiorcea-Paquim, Ana Maria\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Estudo Geral |
| datacite.creators.creator.creatorName.fl_str_mv | Chiorcea-Paquim, Ana Maria |
| datacite.date.Accepted.fl_str_mv | 2023-10-27T00:00:00Z |
| datacite.date.available.fl_str_mv | 2023-10-27T00:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | flavonoids polyphenols phenolic compounds electrochemistry electrochemical sensing antioxidant |
| datacite.titles.title.fl_str_mv | Electrochemistry of Flavonoids: A Comprehensive Review |
| dc.contributor.none.fl_str_mv | Estudo Geral |
| dc.creator.none.fl_str_mv | Chiorcea-Paquim, Ana Maria |
| dc.date.Accepted.fl_str_mv | 2023-10-27T00:00:00Z |
| dc.date.available.fl_str_mv | 2023-10-27T00:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/10316/111831 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | MDPI |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | flavonoids polyphenols phenolic compounds electrochemistry electrochemical sensing antioxidant |
| dc.title.fl_str_mv | Electrochemistry of Flavonoids: A Comprehensive Review |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Flavonoids represent a large group of aromatic amino acids that are extensively disseminated in plants. More than six thousand different flavonoids have been isolated and identified. They are important components of the human diet, presenting a broad spectrum of health benefits, including antibacterial, antiviral, antimicrobial, antineoplastic, anti-mutagenic, anti-inflammatory, anti-allergic, immunomodulatory, vasodilatory and cardioprotective properties. They are now considered indispensable compounds in the healthcare, food, pharmaceutical, cosmetic and biotechnology industries. All flavonoids are electroactive, and a relationship between their electron-transfer properties and radical-scavenging activity has been highlighted. This review seeks to provide a comprehensive overview concerning the electron-transfer reactions in flavonoids, from the point of view of their in-vitro antioxidant mode of action. Flavonoid redox behavior is related to the oxidation of the phenolic hydroxy groups present in their structures. The fundamental principles concerning the redox behavior of flavonoids will be described, and the phenol moiety oxidation pathways and the effect of substituents and experimental conditions on flavonoid electrochemical behavior will be discussed. The final sections will focus on the electroanalysis of flavonoids in natural products and their identification in highly complex matrixes, such as fruits, vegetables, beverages, food supplements, pharmaceutical compounds and human body fluids, relevant for food quality control, nutrition, and healthcare research. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | estudogl_7b2dbbf86a5cc4cb2d5fc167a4af3503 |
| identifier.url.fl_str_mv | https://hdl.handle.net/10316/111831 |
| inst_facet_str | urn:organizationAcronym:uc{{{_:::_}}}Universidade de Coimbra |
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| institution | Universidade de Coimbra |
| instname_str | Universidade de Coimbra |
| language | eng |
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| network_name_str | Estudo Geral - Universidade de Coimbra |
| oai_identifier_str | oai:estudogeral.uc.pt:10316/111831 |
| organization_str_mv | urn:organizationAcronym:uc |
| person_str_mv | Chiorcea-Paquim, Ana Maria |
| publishDate | 2023 |
| publisher.none.fl_str_mv | MDPI |
| repo_facet_str | urn:repositoryAcronym:estudogl{{{_:::_}}}Estudo Geral - Universidade de Coimbra |
| reponame_str | Estudo Geral - Universidade de Coimbra |
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| service_str_mv | urn:repositoryAcronym:estudogl |
| spelling | engMDPIengFlavonoids represent a large group of aromatic amino acids that are extensively disseminated in plants. More than six thousand different flavonoids have been isolated and identified. They are important components of the human diet, presenting a broad spectrum of health benefits, including antibacterial, antiviral, antimicrobial, antineoplastic, anti-mutagenic, anti-inflammatory, anti-allergic, immunomodulatory, vasodilatory and cardioprotective properties. They are now considered indispensable compounds in the healthcare, food, pharmaceutical, cosmetic and biotechnology industries. All flavonoids are electroactive, and a relationship between their electron-transfer properties and radical-scavenging activity has been highlighted. This review seeks to provide a comprehensive overview concerning the electron-transfer reactions in flavonoids, from the point of view of their in-vitro antioxidant mode of action. Flavonoid redox behavior is related to the oxidation of the phenolic hydroxy groups present in their structures. The fundamental principles concerning the redox behavior of flavonoids will be described, and the phenol moiety oxidation pathways and the effect of substituents and experimental conditions on flavonoid electrochemical behavior will be discussed. The final sections will focus on the electroanalysis of flavonoids in natural products and their identification in highly complex matrixes, such as fruits, vegetables, beverages, food supplements, pharmaceutical compounds and human body fluids, relevant for food quality control, nutrition, and healthcare research.application/pdfporElectrochemistry of Flavonoids: A Comprehensive ReviewChiorcea-Paquim, Ana MariaHostingInstitutionOrganizationalEstudo Gerale-mailmailto:inf@sib.uc.ptinf@sib.uc.ptISSNIsPartOf1422-0067DOIIsPartOf10.3390/ijms2421156672023-10-272023-10-27T00:00:00Z2023-10-27T00:00:00ZHandlehttps://hdl.handle.net/10316/111831http://purl.org/coar/access_right/c_abf2open accessflavonoidspolyphenolsphenolic compoundselectrochemistryelectrochemical sensingantioxidant8260545 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articleapplication/pdfhttps://estudogeral.uc.pt/bitstream/10316/111831/1/Electrochemistry-of-Flavonoids-A-Comprehensive-ReviewInternational-Journal-of-Molecular-Sciences.pdf |
| spellingShingle | Electrochemistry of Flavonoids: A Comprehensive Review Chiorcea-Paquim, Ana Maria flavonoids polyphenols phenolic compounds electrochemistry electrochemical sensing antioxidant |
| status | SINGLETON |
| subject.fl_str_mv | flavonoids polyphenols phenolic compounds electrochemistry electrochemical sensing antioxidant |
| title | Electrochemistry of Flavonoids: A Comprehensive Review |
| title_full | Electrochemistry of Flavonoids: A Comprehensive Review |
| title_fullStr | Electrochemistry of Flavonoids: A Comprehensive Review |
| title_full_unstemmed | Electrochemistry of Flavonoids: A Comprehensive Review |
| title_short | Electrochemistry of Flavonoids: A Comprehensive Review |
| title_sort | Electrochemistry of Flavonoids: A Comprehensive Review |
| topic | flavonoids polyphenols phenolic compounds electrochemistry electrochemical sensing antioxidant |
| topic_facet | flavonoids polyphenols phenolic compounds electrochemistry electrochemical sensing antioxidant |
| url | https://hdl.handle.net/10316/111831 |
| visible | 1 |
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