No dia três de fevereiro, tivemos o prazer de entrevistar o Dr. André Novo. Este jovem e promissor investigador – que adquiriu uma relevância além-fronteiras depois de ter recebido um prémio atribuído pela European Federation of Sports Medicine Association, no âmbito do seu inovador trabalho de investigação sobre a capacidade funcional de pacientes em hemodiálise - nasceu a 21 de Abril de 1983 e, para além de ser licenciado em Enfermagem especializou-se em Enfermagem de Reabilitação e possui um doutoramento em Ciências da Atividade Física e do Desporto. André Novo, atualmente, é docente do Instituto Politécnico de Bragança e apesar de, como assumiu, o seu trabalho lhe deixar muito pouco tempo disponível, aceitou encontrar-se connosco, para nos esclarecer sobre algumas questões relativas ao seu excecional percurso académico e profissional. Ao longo de todo o diálogo, mostrou-se sempre bastante simpático, divertido e recetivo às nossas perguntas.

Considerando que o consumo de pescado é uma fonte importante de exposição ao metilmercúrio, a Comissão Europeia recomendou aos Estados- -membros que estabelecessem recomendações para o seu consumo. Assim, tendo sido criado um grupo de trabalho, é objetivo deste artigo apresentar o trabalho desenvolvido para a elaboração das recomendações de consumo de pescado adaptadas à população portuguesa, tendo em conta o padrão nacional de consumo de peixe e as espécies consumidas. A definição das recomendações assentou na realização de um estudo de avaliação de risco-benefício associado ao consumo de pescado. Esta metodologia permitiu identificar dois grupos populacionais sujeitos a recomendações distintas: para a população em geral recomenda-se uma frequência de consumo de 4 a 7 vezes por semana e, para a população vulnerável, uma frequência de 3 a 4 vezes por semana das espécies com médio e baixo teor de mercúrio, devendo ser evitado o consumo das espécies com elevado teor de mercúrio. Estas recomendações foram divulgadas num evento público e deverão ser alvo de esforços adicionais para chegarem à população vulnerável, constituída por mulheres grávidas, mulheres a amamentar e crianças até aos 10 anos.

Introduction: Even though the risk of COVID-19 in pregnancy may be increased, large-scale studies are needed to better understand the impact of the infection in this population. The aim of this study is to describe obstetric complications and the rate of vertical transmission in pregnant women with SARS-CoV-2 infection. Material and Methods: Detected cases of SARS-CoV-2 infection in pregnancy were registered in Portuguese hospitals by obstetricians. Epidemiological, pregnancy and childbirth data were collected. Results: There were 630 positive cases in 23 Portuguese maternity hospitals, most at term (87.9%) and asymptomatic (62.9%). The most frequent maternal comorbidity was obesity. The rates of preterm birth and small-to-gestational-age were 12.1% and 9.9%, respectively. In the third trimester, 2.9% of pregnant women required respiratory support. There were eight cases (1.5%) of fetal death, including two cases of vertical transmission. There were five cases of postpartum respiratory degradation, but no maternal deaths were recorded. The caesarean section rate was higher in the first than in the second wave (68.5% vs 31.5%). RT-PCR SARS-CoV-2 positivity among newborns was 1.3%. Conclusion: SARS-Cov-2 infection in pregnancy may carry increased risks for both pregnant women and the fetuses. Individualized surveillance and the prophylaxis of this population with vaccination. is recommended in these cases.

Introduction: Fish is an important part of the Portuguese diet and a major source of long-chain omega-3 fatty acids. However, it also represents the main dietary source of methylmercury (MeHg), a neurotoxic compound especially harmful during critical stages of development such as pregnancy and early childhood. In response to European Commission Recommendation EU 2022/1342, Portugal undertook a national initiative to assess MeHg exposure and derive population-based consumption guidelines. Methodology: A multidisciplinary working group comprising six public institutions and coordinated by the Directorate-General for Food and Veterinary (DGAV) was established in 2018. The team performed a quantitative risk–benefit assessment (RBA) combining national data on MeHg, EPA, and DHA levels in commonly consumed fish species with food consumption data from the National Food and Physical Activity Survey (IAN-AF 2016). The assessment considered both the toxicological risks of MeHg and the nutritional benefits of omega-3 fatty acids. Results: The RBA showed that, for the general population, the benefits of fish consumption outweigh the risks of MeHg exposure. However, for vulnerable groups - pregnant and breastfeeding women and children under 10 years—the risks were more significant. As a result, differentiated dietary recommendations were developed. For the general population, a frequency of 4–7 servings per week of any fish species was advised. For vulnerable groups, 3–4 servings per week of fish species with medium to low MeHg levels were recommended, while species with high MeHg content (e.g., fresh tuna, swordfish, shark) should be avoided. Conclusions: The resulting recommendations were disseminated through a multilingual infographic, public presentation, and press release. Additional outreach actions targeting health professionals and school meal providers are planned to increase awareness among at-risk populations. Topic relevance: This work exemplifies a science-based approach to public health policy, combining food safety and nutrition to inform national dietary guidelines, with direct implications for risk communication and health promotion.

Brazilian COVID-19 Registry Investigators: Alexandre Vargas Schwarzbold, Amanda de Oliveira Maurílio, Ana Lara Rodrigues Monteiro de Barros, Ana Luiza Bahia Alves Scotton, Alfonso J Rodríguez-Morales, Anderson Lacerda Dos Reis, André Soares Moura Costa, Argenil José Assis de Oliveira, Bárbara Lopes Farace, Carla Thais Cândida Alves da Silva, Carolina Marques Ramos, Christiane Corrêa Rodrigues Cimini, Cíntia Alcantara de Carvalho, Daniel Vitório Silveira, Daniela Ponce, Emanuele Marianne Souza Kroger, Euler Roberto Fernandes Manenti, Fernanda Barbosa Lucas, Fernanda d'Athayde Rodrigues, Fernando Anschau, Fernando Antonio Botoni, Frederico Bartolazzi, Gabriela Petry Crestani, Guilherme Fagundes Nascimento, Helena Carolina Noal, Helena Duani, Heloisa Reniers Vianna, Henrique Cerqueira Guimarães, Joice Coutinho de Alvarenga, Júlia Drumond Parreiras de Morais, Juliana Machado Rugolo, Lara Monalyza Gonçalves Franco, Leila Beltrami Moreira, Leonardo Seixas de Oliveira, Lílian Santos Pinheiro, Liliane Souto Pacheco, Luciane Kopittke, Luciano de Souza Viana, Luis Cesar Souto de Moura, Luisa Elem Almeida Santos, Máderson Alvares de Souza Cabral, Maíra Dias Souza, Marcela Gonçalves Trindade Tofani, Marconi Franco da Silveira, Marcus Vinicius de Melo Andrade, Maria Angélica Pires Ferreira, Maria Aparecida Camargos Bicalho, Maria Auxiliadora Parreiras Martins, Maria Clara Pontello Barbosa Lima, Mariana Balbinot Borges, Mariana de Braga Lima Carvalho Canesso, Matheus Carvalho Alves Nogueira, Meire Pereira de Figueiredo, Milton Henriques Guimarães Junior, Mychelle Stefany Santos Almeida, Mônica Aparecida de Paula de Sordi, Natália da Cunha Severino Sampaio, Neimy Ramos de Oliveira, Paulo Tarso Lima Vianna, Pedro Guido Soares Andrade, Pedro Ledic Assaf, Rafael Fusaro Aguiar Oliveira, Rafael Lima Rodrigues de Carvalho, Rafaela Dos Santos Charão de Almeida, Raphael Castro Martins, Reginaldo Aparecido Valacio, Ricardo Bertoglio Cardoso, Ricardo Braga Coelho, Roberta Pozza, Rodolfo Lucas Silva Mourato, Rodrigo Costa Pereira Vieira, Roger Mendes de Abreu, Rufino de Freitas Silva, Saionara Cristina Francisco, Silvana Mangeon Mereilles Guimarães, Silvia Ferreira Araújo, Talita Fischer Oliveira, Tatiana de Vargas, Tatiani Oliveira Fereguetti, Thalita Martins Lage, Thulio Henrique Oliveira Diniz, Veridiana Baldon Dos Santos

Introduction: Even though the risk of COVID-19 in pregnancy may be increased, large-scale studies are needed to better understand the impact of the infection in this population. The aim of this study is to describe obstetric complications and the rate of vertical transmission in pregnant women with SARS-CoV-2 infection.Material and Methods: Detected cases of SARS-CoV-2 infection in pregnancy were registered in Portuguese hospitals by obstetricians. Epidemiological, pregnancy and childbirth data were collected.Results: There were 630 positive cases in 23 Portuguese maternity hospitals, most at term (87.9%) and asymptomatic (62.9%). The most frequent maternal comorbidity was obesity. The rates of preterm birth and small-to-gestational-age were 12.1% and 9.9%, respectively. In the third trimester, 2.9% of pregnant women required respiratory support. There were eight cases (1.5%) of fetal death, including two cases of vertical transmission. There were five cases of postpartum respiratory degradation, but no maternal deaths were recorded. The caesarean section rate was higher in the first than in the second wave (68.5% vs 31.5%). RT-PCR SARS-CoV-2 positivity among newborns was 1.3%.Conclusion: SARS-Cov-2 infection in pregnancy may carry increased risks for both pregnant women and the fetuses. Individualized surveillance and the prophylaxis of this population with vaccination. is recommended in these cases.

Introduction: Even though the risk of COVID-19 in pregnancy may be increased, large-scale studies are needed to better understand the impact of the infection in this population. The aim of this study is to describe obstetric complications and the rate of vertical transmission in pregnant women with SARS-CoV-2 infection. Material and methods: Detected cases of SARS-CoV-2 infection in pregnancy were registered in Portuguese hospitals by obstetricians. Epidemiological, pregnancy and childbirth data were collected. Results: There were 630 positive cases in 23 Portuguese maternity hospitals, most at term (87.9%) and asymptomatic (62.9%). The most frequent maternal comorbidity was obesity. The rates of preterm birth and small-to-gestational-age were 12.1% and 9.9%, respectively. In the third trimester, 2.9% of pregnant women required respiratory support. There were eight cases (1.5%) of fetal death, including two cases of vertical transmission. There were five cases of postpartum respiratory degradation, but no maternal deaths were recorded. The caesarean section rate was higher in the first than in the second wave (68.5% vs 31.5%). RT-PCR SARS-CoV-2 positivity among newborns was 1.3%. Conclusion: SARS-Cov-2 infection in pregnancy may carry increased risks for both pregnant women and the fetuses. Individualized surveillance and the prophylaxis of this population with vaccination. is recommended in these cases.

Educação e Pesquisa agradece aos especialistas abaixo relacionados/as, que colaboraram com a revista no período de out. 2022 a out. 2023. Allan Moreira Xavier Adelar Aparecido Sampaio Ademir Macedo Nascimento Adriana Fischer Adriana Regina Braga Alba García Barrera Alessandra Jacqueline Vieira Alex Bellucco do Carmo Alexandre Barbosa Pereira Alexandre Bortolini Alexandre Saul Alice Maria Corrêa Medina Allan Moreira Xavier Álvaro Pérez García Amelia Cristina Abreu Artes Ana Luisa Teixeira de Menezes Ana Luiza Jesus da Costa Ana Lydia Vasco de Albuquerque Peixoto Ana Paula Berberian André Luiz Correia Gonçalves de Oliveira Andrea Perosa Saigh Jurdi Andrea Soares Wuo Andresa de Souza Ugaya Andressa Mafezoni Caetano Andreza Barbosa Anete Abramowicz Ângela Pereira Teixeira Victoria Palma Ângela Viana Machado Fernandes Antonio de Padua Palacios Rodríguez Antonio Henrique Pinto Antonio Palacios Rodríguez Arlene Ricoldi Arliene Stephanie Menezes Pereira Arlindo da Silva Lourenço Barbara Corominas Valerio Belén González-Laguillo Betânia de Oliveira Laterza Ribeiro Bruno F. Gonçalves Bruno Gawryszewski Bruno Miguel Ferreira Gonçalves Camila Lima Coimbra Carla Guanaes Lorenzi Carlos Alberto Ferreira Carlos Herold Jr Carmen Fontes de Souza Teixeira Carolina Donato da Silva Carolina Mostaro Neves da Silva Carolina Zuccarelli Catarina Tomás Célia Cristina de Figueiredo Cassiano Celia Elizabete Caregnato Célia Maria Haas Celina Aparecida Almeida Pereira Abar Claudemir Belintane Claudete Pagotto Cláudia Cristina do Lago Borges Clóvis Trezzi Cristiane Sander Daielly Melina Nassif Mantovani Daniel de Carvalho Lopes Daniel Ríos Muñoz Daniela Aparecida Eufrásio Danila Di Pietro Zambianco Danilo Rothberg Dario Fiorentini David Antonio da Costa Debora Cristina Goulart Débora Maria do Nascimento Décio Gatti Júnior Denise Aparecida Corrêa Denise Grinspum Denise Meyrelles de Jesus Denise Trento Rebello Souza Diana Maria Farias Camero Diana Vidal Diego dos Santos Reis Dirce Djanira Pacheco e Zan Dislane Zerbinatti Moraes Edison Trombeta de Oliveira Edivaldo Góis Junior Eduardo Perioli Junior Elias Evangelista Gomes Elias Manuel Said Hung Élida Lopes Miranda Elmir de Almeida Émerson de Pietri Ermelinda Moutinho Pataca Ernesto Colomo Magaña Evandro Salvador Alves de Oliveira Evelise Maria Labatut Portilho Fabiana A. Jardim Fábio Araujo de Souza Fábio Hoffmann Pereira Fátima Niemeyer da Rocha Felipe de Souza Tarábola Fernanda Rossi Fernando Cezar Vieira Malange Fernando Luiz Zanetti Fernando Rodrigues de Oliveira Filipe Rafael Gracioli Flavio Alex de Oliveira Carvalhaes Francisco David Guillén Gámez Francisco José Carvalho Mazzeu Francisco José Figueiredo Coelho Gabriela Medeiros Nogueira Gabriela Schneider Geraldo Magela Pereira Leão Gisele Adriana Maciel Pereira Gisele Toassa Gislene Moreira Graça Regina Franco da Silva Reis Gustavo de Oliveira Figueiredo Gustavo Henrique Moraes Harlon Romariz Helena Altmann Helena Maria Barroso Carvalho Heloísa Helena Pimenta Rocha Heloisa Salles Gentil Herman Fialho Fumiã Hugo Heredia Ponce Iris Orosia Campos Bandrés Isabel Porto Filgueiras Isabela Bilecki da Cunha Isaurora Cláudia Martins de Freitas Jaison Marques Luiz Javier Muñoz Jerusa Vilhena de Moraes João Henrique da Silva João Luiz Horta Neto José Alves da Silva José Ricardo de Carvalho Mesquita Ayres Juliana Batista dos Reis Juliana de Souza Silva Juliana Ribeiro De Vargas Jussara Santos Pimenta Karina Soledad Maldonado Molina Karla Raphaella Costa Pereira Katiuscia C. vargas Antunes Kelly Ludkiewicz Alves Kimi Tomizaki Ladislau Ribeiro do Nascimento Lais Donida Leandro R. Pinheiro Léia Teixeira Lacerda Leila Maria Inoue Leila Pio Mororó Leonardo da Silveira Borne Leonir Lorenzetti Leonor Torres Lisângela Kati do Nascimento Lorena Marina dos Santos Miguel Luana Motta Lucelida de Fatima Maia da Costa Lucia Pereira Leite Luciana Massi Luciane Fernandes de Goes Lucila Pesce Lucy Leal Melo-Silva Ludmila Oliveira Holanda Cavalcante Luis Jacob Lygia de Sousa Viegas Manoel Oriosvaldo de Moura Manuel Francisco Romero Oliva Marcela Jarpa Azagra Marcele Frossard Marcelo Augusto Totti Marcelo El Khouri Buzato Marcelo Moreira Antunes Marcelo Rodrigues Conceicao Marcia Angela da Silva Aguiar Márcia Aparecida Jacomini Márcio Magalhães Fontoura Marco Antonio Bueno Filho Marcos Vinicius Francisco Marcus Vinicius da Cunha Margarida Belchior Margarida Belchior Maria Angela Borges Salvadori Maria Antônia de Souza Maria Aparecida Bergamaschi María Armario Bernal Maria da Glória Calado Maria da Graça Jacintho Setton Maria de Fátima Almeida Martins Maria de Fátima Barbosa Abdalla Maria de Lourdes Haywanon Santos Araujo Maria do Horto Salles Tiellet Maria Eugênia L.M. Castanho Maria Goreti Amboni Stadtlober Maria Letícia B. P. Nascimento Maria Margarida Pereira de Lima Gomes Marian Ávila de Lima e Dias Marilia Pontes Esposito Marina Avelar Marina Cyrino Marina Jorge da Silva Marina Salles Leite Lombardi Maritânia Salete Salvi Rafagnin Marta Gouveia de Oliveira Rovai Martha Marandino Matheus Monteiro Nascimento Maurício Perondi Messias Furtado da Silva Michela Tuchapesk da Silva Milton Rosa Miriam Viviane Baron MIryam Bonadiu Pelosi Mônica Cristina Garbin Mônica Dias Peregrino Ferreira Monica Ribeiro da Silva Nádia Maciel Falcão Natália de Lacerda Gil Neide Luzia de Rezende Neli Maria Mengalli Newton Dângelo Nilson Rogério da Silva Núbio Delanne Ferraz Mafra Nuno Dorotea Olivia Morais de Medeiros Neta Patricia da Silva Sessa Patrício Carneiro Araújo Pauline Vielmo Miranda Paulo Cesar Rodrigues Carrano Paulo Henrique Fernandes Silveira Paulo Lima Junior Paulo Sérgio Garcia Pedro Roberto Jacobi Pedro Xavier Russo Bonetto Priscila Benitez Priscila Keiko Cossual Sakurada Rafael Cava Mori Raimunda Abou Gebran Raquel de Oliveira Mendes Raquel Milani Regiane Helena Bertagna Regina Cândida Ellero Gualtieri Regina Helena Silva Simões Régis Henrique dos Reis Silva Relma Urel Carbone Carneiro Renato Pontes Costa Ricardo Boklis Golbspan Ricardo Gonçalves Severo Rita de Cassia Gallego Roberto da Silva Rodrigo Diego de Souza Rogério Diniz Junqueira Rogério Lessa Horta Rogério Rodrigues Romero Tori Rosa Fátima de Souza-Chaloba Rosa Maria Bueno Fischer Rosana Louro Ferreira Ssilva Rosângela Malachias Roseane Andrelo Rui Pedro Campos Bento Barros Candeias Samuel Mendonça Sandoval Nonato Gomes Santos Sandra Unbehaum Sauloeber Tarsio De Souza Sebastião Jacinto dos Santos Selma Garrido Pimenta Sérgio Paulino Abranches Shirlei Rezende Sales Shirley de Lima Ferreira Arantes Silvania Sousa do Nascimento Silvio Ricardo Gomes Carneiro Sonia García-Segura Sonia Maria da Silva Junqueira Sonia Maria Guedes Gondim Stefannie de Sá Ibraim Sueli Fanizzi Sueli Guadelupe de Lima Mendonça Suerde Miranda de Oliveira Brito Tânia Guedes Magalhães Tanya Amara Felipe de Souza Tatiana Bolivar Lebedeff Tatiane de Freitas Ermel Terciane Ângela Luchese Thaís Cristina Rodrigues Tezani Thiago dos Santos Molina Vanessa Teixeira Pipinis Verónica A. Quintanilla Batallanos Victor Hugo Nedel Oliveira Vilson José Leffa Vitor Sérgio Ferreira Viviane Briccia Viviane Potenza Guimarães Pinheiro Wagner Teixeira Dias Zaqueu Vieira Oliveira Zena Eisenberg

Agradecimentos Educação e Pesquisa agradece aos especialistas abaixo relacionados, que colaboraram com a revista no período de out. 2020 a out. 2021. Acacia Zeneida Kuenzer Ademir Donizeti Caldeira Adenize Costa Acioli Adriana Bauer Adriana Melo Adriana Santiago Rosa Dantas Adriane Knoblauch Adriano Vieira de Carvalho Agnaldo Arroio Aguinaldo Cesar Surdi Alan Augusto Moraes Ribeiro Alberto Moreno-Doña Alex Bellucco do Carmo Alexander Armando Cordoves Santiesteban Alexandre Pianelli Godoy Alexandre Ramos de Azevedo Alexandre Saul Alexandre Toaldo Bello Alexsandro do Nascimento Santos Alfredo Gabriel Buza Alice Casimiro Lopes Alice Ribeiro Casimiro Lopes Alicia Beatriz Gutiérrez Aline de Morais Limeira Pasche Aline Silva Dejosi Nery Allan Kenji Seki Américo Rodrigues de Almeida Neto Amurabi Oliveira Ana Alice Vilas Boas Ana Beatriz Gomes Pimenta de Carvalho Ana Claudia D. Capistrano de Oliveira Ana Claudia Urban Ana Cristina Coll Delgado Ana Elisa Spaolonzi Queiroz Assis Ana Gladcheff Ana Lúcia Calbaiser da Silva Ana Lúcia Cunha Duarte Ana Lúcia Sarmento Henrique Ana Maria Di Grado Hessel Ana Maria Fonseca de Almeida Ana Maria Nogales Vasconcelos Ana Paula Abrahamian de Souza Ana Paula dos Santos de Sá Anderson de Carvalho Pereira André da Silva Mello André Dalben André Luiz C. Gonçalves de Oliveira Andre Luiz dos Santos André Rosalém-Signorelli Andréa Barbosa Gouveia Andrea Cristiane Maraschin Bruscato Andrea Cristina Versuti Andréia Arruda Guidetti Andréia Jaqueline Devalle Rech Andrés Donoso Romo Andreza Barbosa Angela Maria Cristina Uchoa A. Branco Antonia Almeida Silva Antonia Terra de Calazans Fernandes Antonio Alberto Pereira Antonio Hilario Aguilera Urquiza Barbara Lutaif Bianchini Benerval Pinheiro Santos Bianca Rigamonti Valeiro Garcia Bruna Soares Polachini Bruno Nunes Batista Camila Ferreira da Silva Candido Alberto da Costa Gomes Carlos Betlinski Carlos Herold Junior Carola Gabriela Sepúlveda Vásquez Carolina Mostaro Neves da Silva Carolina Rodrigues de Souza Caroline Fockink Ritt Cássio José de Oliveira Silva Silva Catarina de Almeida Santos Catarina Mangas Célia Cristina de Figueiredo Cassiano Célia Regina Batista Serrão César Augusto Minto Cesar Lehmann Albornoz Charliton José dos Santos Macado Christian Fernando Ribeiro Guimarães Vinci Christiane Coutheux Trindade Cibele Krause Lemke Cibele Noronha de Carvalho Cileda Santos Sant’Anna Perrella Clarice Monteiro Escott Claudete Pagotto Claudia Barcelos de Moura Abreu Cláudia Hilsdorf Rocha Cláudio Rodrigues da Silva Cleci T. Werner da Rosa Cleriston Izidro dos Anjos Clériston Silva dos Anjos Cristiane Machado Cristiano Alberto Muniz Cristiano Barbosa de Moura Cristina Ferreira de Assis Cristovam da Silva Alves Cynthia Martínez-Garrido Daielly Melina Nassif Mantovai Daniel Campos de Carvalho Daniel Ríos Muñoz Daniel Tojeira Cara Daniela Aparecida Eufrásio Daniela da Costa Britto Pereira Lima Daniele Cristina Souza Danilo Martuccelli David Antonio da Costa Debora Cristina Goulart Debora Cristina Piotto Denilson Soares Cordeiro Denise Madeira de Castro e Silva Denize de Aguiar Xavier Sepulveda Diana Patricia Ferreira de Santana Diana Vidal Diego dos Santos Reis Dirce Aparecida Foletto Moraes Dislane Zerbinatti Moraes Eder Coelho Paula Edilene Maria da Silva Eduardo Di Deus Elaine Prodócimo Elenilton Vieira Godoy Elias Manuel Said Hung Élida Lopes Miranda Elie George Guimarães Ghanem Jr. Elio Carlos Ricardo Elisabeth Mazeron Machado, Elisangela Lazarou Tarraço Elisangela Tarraco Eliseo Alfonso Barca Lozano Elma Júlia Gonçalves de Carvalho Emilia Peixoto Vieira Érica Aparecida Garrutti de Lourenço Érica Santana Silveira Nery Ermelinda Moutinho Pataca Eromi Izabel Hummel Etienne Barbosa Baldez Evaldo Epiolli Evelise Maria Labatut Portilho Fabiana Cristina Frigieri de Vitta Fabiana Silva Fernandes Fabiany De Cássia Tavares Silva Fábio Hoffmann Pereira Faní Quitéria Nascimento Rehem Fátima Niemeyer da Rocha Fátima Suely Ribeiro Cunha Fernanda de Jesus Costa Fernanda Pinto de Aragão Quintino Fernanda Rossi Fernanda Sarturi Fernando César Silva Fernando Cezar Vieira Malange Fernando Protetti Fernando Rezende da Cunha Junior Flávia dos Santos Soares Flávia Inês Schilling Flavia Pereira Xavier Flávio Caetano da Silva Flávio Santiago Franciane Maria Araldi Francisco García Marcos Fredy Enrique González Gardia Maria Vargas George Coutinho Geraldo Eustáquio Moreira Géssica Priscila Ramos Gilberto Ferreira da Silva Giovanna Modé Magalhães Gisele Belusso Gladis Massini-Cagliari Glauco da Silva Aguiar Graciella Watanabe Guilherme Gabriel Ballande Romanelli Hartmut Günther Helder Boska de Moraes Sarmento Henrique César da Silva Henrique Evaldo Janzen Herman Fialho Fumiã Hermengarda Alves Lüdke Hivy Damasio Araújo Mello Hormindo Pereira de Souza Junior Iara Tatiana Bonin Ilka Miglio de Mesquita Ingrid Hötte Ambrogi Ione Ribeiro Valle Iracema Santos do Nascimento Íris Susana Pires Pereira Isabel Melero Bello Itale Luciane Cericato Ivanildo Lubarino Piccoli dos Santos Jaciara de Sá Carvalho Jackson Gois da Silva Jaqueline Dourado do Nascimento Jefferson Mainardes Jerusa Vilhena de Moraes Joaquim ramos Joedson Brito dos Santos Joice Sousa Costa Jonas Rangel de Almeida Jorge Dorfman Knijnik José Carlos Miguel José Carlos Santos José Cezinaldo Rocha Bessa José Cláudio Sooma Silva José Marcelino de Rezende Pinto José Pedro Boufleuer José Pedro Cerdeira Júlia Catani Juliana de Souza Silva Julio César Tovar-Gálvez, Jurema Luzia de Freitas Sampaio, Jussara Cristina Barboza Tortella Karina Carrasqueira Lopes Karina Soledad Maldonado Molina Karla Mendonça Menezes Katia Adair Agostinho Katia Arillha Fiorentino Nanci Katia Cristina Silva Forli Bautheney Katia Cristina Stocco Smole Kátia Liége Nunes Gonçalves Katiuscia Cristina Vargas Antunes Keila Deslandes Keli Cristina Conti Kimi Aparecida Tomizaki Kristie Helene Novoa Durante Leda Maria de Oliveira Rodrigues Léia Teixeira Lacerda Leonardo Borne Leôncio José Gomes Soares Leonilda do Nascimento da Silva Lia da Rocha Lordelo Lílian do Valle Lisiane Machado de Oliveira-Menegotto Livia Suassuna Lucas Nascimento Ferraz Costa Lúcia Helena Sasseron Lucia Maria Salgado dos Santos Lombardi Lúcia Pereira Leite Luciana Esmeralda Ostetto Luciana Garcia Mello Luciana Paula Vieira de Castro Lucila Maria Pesce de Oliveira Luis Alberto Guzmán Palacios Luís Paulo Leopoldo Mercado Luiz Antonio Callegari Coppi Luiz Eduardo P. Basto Tourinho Dantas Luiz Roberto Alves Maévi Anabel Nono Manuel Alejandro Giovine Marcelo Augusto Totti Marcelo Rodrigues Conceição Márcia Buss-Simão Márcia Helena Alvim Marcia Machado de Lima Márcio de Oliveira Marco Braga Marcos Barbosa Oliveira Marcos Fernando Ruiz Ruiz Marcos Garcia Neira Marcos Nascimento Magalhães Marcus Vinícius Medeiros Pereira Maria Amélia Rosário Santoro Franco Maria Aparecida de Oliveira Freitas Maria Aparecida Mello Maria Beatriz Luce Maria Cândida Borges de Moraes Maria Cristina Cavaleiro Maria da Conceição F. B. Sgadari Pas Maria de Lourdes Bernartt Maria Dilnéia Espíndola Fernandes Maria do Carmo de Lacerda Peixoto Maria Eugênia de L. Montes Castanho Maria Eulina Pessoa de Carvalho Maria Fernanda Rezende Nunes Maria Graça Jacintho Setton Maria Helena Câmara Bastos Maria José da Silva Fernandes Maria Jose Dias De Freitas Maria Letícia B. Pedroso Nascimento Maria Teresa Jacinto Sarmento Maria Teresa Santos Cunha María Victoria Mateo García Maria Zenaide Alves Marian Ávila de Lima e Dias Marieta Gouvêa de Oliveira Penna Marília Moschkovich Marina Rezende Bazon Marinez França de Souza Mário Henrique Gomes Mario Hernández Hernández-Nodarse Mario Luiz Neves de Azevedo Marisa Eugênia Melillo Meira Maritania Salete Salvi Rafagnin Marizete Lucini Marta Genú Soares Matheus Henrique da Fonsêca Barros Matheus Monteiro Nascimento Maurilane de Souza Biccas Mauro Cavalcante Pequeno Michele Viviene Carbinatto Michelle Prazeres Cunha Miguel Luiz Ambrizzi Milton Rosa Miriam Sonlleva Velasco Mirian Jorge Warde Mônica Appezzato Pinazza Monica Villaça Gonçalves Mylene Nogueira Teixeira Nara Jorge Wellausen Vieira Nathalie de Almenda Bressiani Naylla Morais de Souxa Neiva Furlin Neli Maria Mengalli Neusa Maria Dal Ri Nicholas Davies Nyuara Araújo da Silva Mesquita Ocimar Munhoz Alavarse Paloma Rezende de Oliveira Patrício Carneiro Araújo Patricio Lepe-Carrión Paula Francisca da Silva Paulo Vitor de Souza Pinto Pedro Angelo Pagni Pedro Ganzeli Pedro Guilherme Rocha dos Reis Pedro Jorge Caetano Pedro Ribeiro Mucharreira Poliana Bruno Zuin Preciosa Fernandes Priscila Monteiro Chaves Raiane Florentino Rainri Back Raíssa de Oliveira Chappaz Raquel Fontes Borghi Raquel Lazzari Leite Barbosa Raquel Lima Raquel Souza Regina Cândida Ellero Gualtieri Reginaldo Celio Sobrinho Reginaldo Fernando Carneiro Régis Henrique dos Reis Silva Relma Urel Carbone Carneiro Renata Marcílio Cândido Renata Pontes Costa Renato Abreu Lima Renato Marcon Pugliese Ricardo Boklis Golbspan Ricardo Jorge De Sousa Cavalcanti Rinaldo Molina Rinaldo Voltolini Rita de Cassia Gallego Rita Santos Guimarães Roberta Stangherlim Roberto Rafael Dias da Silva Robson Rocha de Souza Júnior Rodison Roberto Santos Rodrigo Diego de Souza Rodrigo Lages e Silva Rodrigo Saballa de Carvalho Rogério Diniz Junqueira Rogério Luis da Rocha Seixas Rogério Vicente Ferreira Romilda Costa Motta Romilda Teodora Ens Ronaldo Rosas Reis Roni Cleber Dias de Menezes Roraima Alves da Costa Filho Rosa Aguilar Verastegui Rosa Fátima de Souza Chaloba Rosa Maria Ferreira da Silva Rosana Amaro Rosana Evangelista da Cruz Rosana Louro Ferreira Silva Rosângela Gavioli Prieto Rosário Silvana Genta Lugli Rosemeire Reis Salomão Barros Ximenes Sandra Maria Zákia Lian Sousa Sandra Regina Simonis Richter Sandra Unbehaum Sergio Antonio Carlos Sergio Baptista dos Santos Sergio Paulino Abranches Silvio Ricardo Gomes Carneiro Silvio Ricardo Munari Machado Simone Rocha Salomão Simone Sarmento Sonia Carbonell Alvares Sonia Kramer Sonia Maria Duarte Grego Sonia Maria Rummert Sonia Maria S.Corrêa de Souza Cruz Sônia Teresinha Sousa Penin Sônia Vanzella Castellar Souzana Mizan Stela Maria Fernandes Marques Stephen M. Hart Sueli Fanizzi Sueli Lima Moreira Suzana dos Santos Gomes Suzana Lopes de Albuquerque Sylvia De Chiaro Tatiana Luiza Rech Telma Ferraz Leal Terezinha Oliveira Terezinha Valim Oliver Gonçalves Tícia Cassiany Ferro Cavalcante Tulio Campos Umberto de Andrade Pinto Valéria Amorim Arantes Valmir Flôres Pinto Vanessa Dias Moretti Vanessa Elias de Oliveira Vanessa Teixeira Pipinis Vania de Vasconcelos Gico Velda Torres Vera Lúcia Guerra Vera Regina Oliveira Diehl Vera Teresa Valdemarin Verilda Speridião kluth Vicente Zatti Vinicio de Macedo Santos Vinicius Catão de Assis Souza Violante F. Magalhães Vivian Batista da Silva Vivian Martins Viviane Fernandes F. Pinto Viviane Potenza Guimarães Pinheiro Viviane Toraci Alonso de Andrade Wagner Rodrigues Silva Wagner Xavier Camargo Waldemar Ferreira Netto Wania Regina Coutinho Gonzalez Wilma Favorito Wivian Weller Yamila Irupé Nuñez Zaqueu Vieira Oliveira Zilda Gláucia Elias Franco Zuleide Simas Silveira      

Objectives: To describe the clinical characteristics, laboratory results, imaging findings, and in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals.Methods: A cohort study of laboratory-confirmed COVID-19 patients who were hospitalized from March 2020 to September 2020 in 25 hospitals. Data were collected from medical records using Research Electronic Data Capture (REDCap) tools. A multivariate Poisson regression model was used to assess the risk factors for in-hospital mortality. Results: For a total of 2,054 patients (52.6% male; median age of 58 years), the in-hospital mortality was 22.0%; this rose to 47.6% for those treated in the intensive care unit (ICU). Hypertension (52.9%), diabetes(29.2%), and obesity (17.2%) were the most prevalent comorbidities. Overall, 32.5% required invasive mechanical ventilation, and 12.1% required kidney replacement therapy. Septic shock was observed in 15.0%, nosocomial infection in 13.1%, thromboembolism in 4.1%, and acute heart failure in 3.6%. Age >= 65 years, chronic kidney disease, hypertension, C-reactive protein 100 mg/dL, platelet count < 100 =109/L, oxygen saturation < 90%, the need for supplemental oxygen, and invasive mechanical ventilation at admission were independently associated with a higher risk of in-hospital mortality. The overall use of antimicrobials was 87.9%. Conclusions: This study reveals the characteristics and in-hospital outcomes of hospitalized patients with confirmed COVID-19 in Brazil. Certain easily assessed parameters at hospital admission were independently associated with a higher risk of death.